Cervical cancer risk after different types of HPV detected during screening
Looks back at screening records to study cervical cancer risk after HPV detection.
Plain-language title generated from the registry record
Registry title: Risk of Cervical Cancer Following Incident, Persistent and History-unknown HPV Detection
Key facts
- Where
- Stockholm, SwedenSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 22 and 70 years old?
Source: NCT07850128, who can take part
Where in Sweden
- Centre for Cervical Cancer Elimination, Department of Clinical Science, Intervention and Technology, Karolinska InstitutetStockholm, SwedenTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Karolinska Institutet
- Trial code
- NCT07850128
- Record updated
- 30 September 2026
- Original description
The goal of this register-based retrospective observational study is to understand the risk of cervical cancer following incident, persistent and history-unknown HPV detection by HPV genotype in healthy women participating in HPV-based cervical screening. The main questions it aims to answer are:Read full original descriptionShow less
Risk of Cervical Cancer Following Incident, Persistent and History-unknown Human Papillomavirus (HPV) Detection by HPV Genotype
The goal of this register-based retrospective observational study is to understand the risk of cervical cancer following incident, persistent and history-unknown HPV detection by HPV genotype in healthy women participating in HPV-based cervical screening. The main questions it aims to answer are:
1. Whether an incident HPV detection with certain HPV genotypes has low risk of cervical cancer in 3 to 5 years thus does not need further clinical assessment before the next screening test? 2. How risky a persistent HPV detection is, and whether persistent detection of any high-risk HPV genotype warrant immediate clinical assessment? 3. How risky a HPV detection is, if no previous HPV test result is available?
As being a register-based retrospective observational study, study subjects will not be asked to do any specific task for this study.
Inclusion: Women living in the Great Stockholm Region in Sweden, at cervical screening ages (age 22-70 years), and having had an HPV positive result in primary HPV test during 2014-2023.
Exclusion: Women without valid personal identity number in the population registry.