NCT07850934Recruiting
Effect of Melatonin on Pulmonary Hypertension in Full Term Neonates
Source: ClinicalTrials.gov · Last updated 22 Oct 2026
Brief summary (registry, in English)
The aim of the study 1. To evaluate safety and efficacy of melatonin as an adjuvant therapy to inhaled nitric oxide generated by NO generator in the treatment of pulmonary hypertension in full term neonates. 2. To assess the effect of inhaled nitric oxide and melatonin on cerebral perfusion.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 52 (estimated)
- First submitted
- 9 Aug 2026
- Start date
- 1 Jul 2025
- Primary completion date
- 1 Nov 2026
- Lead sponsor
- Ain Shams University
- NCT number
- NCT07850934
What you commit to
- Study type: Interventional
- Planned participants: 52
- From 1 Jul 2025 to the primary completion date, 1 Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Major congenital cardiac anomalies especially duct dependent systemic circulation.
- Bleeding tendency.
Other
- Congenital methemoglobinemia.
- Patients on other pulmonary vasodilators
Who the study is looking for
- Term neonates with gestational age ≥ 37 weeks.
- Mean Pulmonary artery pressure greater than 25mmHg with clinical manifestations as tachypnea, tachycardia, hypoxemia and hypotension
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ain Shams University Coordinator of this site? Confirm its status | Cairo | Egypt | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.