Tests a cooling vest during rehabilitation exercise in people with multiple sclerosis
Tests a cooling vest during exercise sessions to see effects on fatigue in multiple sclerosis.
Plain-language title generated from the registry record
Registry title: Cooling During Inpatient Rehabilitation in Persons With MS
Key facts
- Where
- Valens, SwitzerlandSee the site
Where in Switzerland
- Rehabilitation clinic ValensValens, SwitzerlandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Klinik Valens
- Trial code
- NCT07852156
- Record updated
- 1 October 2026
- Original description
The goal of this clinical trial is to shed light on the use of cooling during intensive active training sessions during a three-week multidisciplinary inpatient rehabilitation stay in persons with Multiple Sclerosis. The objectives of this study are:Read full original descriptionShow less
Optimizing Inpatient Rehabilitation - Investigating the Effects of Cooling During Intensive Active Training Sessions on Fatigue in Persons With Multiple Sclerosis
The goal of this clinical trial is to shed light on the use of cooling during intensive active training sessions during a three-week multidisciplinary inpatient rehabilitation stay in persons with Multiple Sclerosis. The objectives of this study are:
* to investigate the effects of one week of using a cooling vest during intensive active training sessions compared with one week of not using a cooling vest during inpatient rehabilitation on the state fatigue in persons with Multiple Sclerosis. * to investigate the effects of one week of using a cooling vest during intensive active training sessions compared with one week of not using a cooling vest during inpatient rehabilitation on the walking capacity, functional lower limb muscle strength, balance and cognition in persons with Multiple Sclerosis. * to investigate the effects of the three-week inpatient rehabilitation on the cardiorespiratory fitness, muscle strength and trait fatigue in persons with Multiple Sclerosis.
Researchers will compare the effects of one week of using a cooling vest during intensive active training sessions with one week of not using a cooling vest during intensive active training sessions during three weeks of inpatient rehabilitation.
Participants will
* Wear a cooling vest during intensive active training sessions for one week * Attend the assessment appointments during study participation * Keep a diary recording their use of a cooling vest during intensive active training sessions
Inclusion: FSMC total score ≥ 43; Adult age (≥ 18 years); A definite MS diagnosis according to the 2024 revised McDonald criteria with relapsing-remitting, primary or secondary progressive phenotypes; Disease severity according to Expanded disability status scale (EDSS) score 3.0-6.0; Subjective perceived heat sensitivity (Yes).
Exclusion: Severe concomitant disease states (i.e. orthopaedic, cardiovascular, metabolic, psychiatric (e.g., substance abuse), other neurological disease states, other serious medical conditions) impairing the ability to participate; Previous enrolment into this study; Cognitive impairment (Montreal Cognitive Assessment, MoCA score < 26); Sudden severe disease progression or falling sick (e.g. bacterial or viral infections) during the study; Inability to follow the study procedures (i.e. participant not fluent in oral and written German language); Participation in another study; Pregnant or lactating women; Intention to become pregnant during this study; Suspected non-compliance; Subjective perceived cold sensitivity (Yes).