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Mailed Stool Test and Reminder Strategies to Increase Colorectal Cancer Screening

Compares reminders and mailed stool tests to boost colorectal cancer screening in adults.

Plain-language title generated from the registry record
Registry title: Mailed FIT-Based Outreach Interventions

Key facts

Where
Singapore, SingaporeSee the 5 sites

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 50 and 80 years old?

Source: NCT07852793, who can take part

Where in Singapore

  • Changi General HospitalSingapore, SingaporeNo longer taking part
  • National Cancer Center SingaporeSingapore, SingaporeNo longer taking part
  • Sengkang General HospitalSingapore, SingaporeNo longer taking part
  • Singapore General HospitalSingapore, SingaporeNo longer taking part
  • SingHealth PolyclinicSingapore, SingaporeNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
National Cancer Centre, Singapore
Trial code
NCT07852793
Record updated
1 October 2026
Original description
Colorectal cancer (CRC) is the second most common cancer and the second leading cause of cancer-related mortality in Singapore. Although annual fecal immunochemical testing (FIT) and periodic colonoscopy are recommended for average-risk adults aged 50-75, only 44.9% of eligible individuals are up to date with CRC screening. Screening participation, adherence to repeat annual FIT, and completion of diagnostic colonoscopy after abnormal FIT results remain suboptimal. This study aims to identify the most effective and cost-effective strategy for increasing CRC screening participation and adherence.Read full original descriptionShow less

Mailed FIT-Based Outreach Interventions vs Usual Care to Increase Uptake of Colorectal Cancer Screening in a Multi-Ethnic Population: A 7-Arm Randomized Controlled Trial

Colorectal cancer (CRC) is the second most common cancer and the second leading cause of cancer-related mortality in Singapore. Although annual fecal immunochemical testing (FIT) and periodic colonoscopy are recommended for average-risk adults aged 50-75, only 44.9% of eligible individuals are up to date with CRC screening. Screening participation, adherence to repeat annual FIT, and completion of diagnostic colonoscopy after abnormal FIT results remain suboptimal. This study aims to identify the most effective and cost-effective strategy for increasing CRC screening participation and adherence.

Inclusion: Eligible individuals are those enrolled with SingHealth Polyclinics aged 50-80 at time of study initiation, who are due for CRC screening (i.e., no FIT within the past year, or no colonoscopy within the past 5-10 years).

Exclusion: Prior diagnosis of CRC, advanced cancer, or palliative care.

ClinicalTrials.gov NCT07852793