Stepwise balloon post-dilation after stent placement in coronary artery disease
Tests stepwise balloon inflation after stent placement in adults with narrowed heart arteries.
Plain-language title generated from the registry record
Registry title: Impact of Stepwise Pressure-Increasing NC Balloon Post-Dilation on Stent Expansion
Key facts
- Where
- Changchun, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with a narrowed coronary artery who need one stent. A balloon is used after the stent to open it fully.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- One coronary artery narrowed by 50% or more, needing a single stent
Main reasons for not taking part
- Unstable blood circulation (hemodynamically unstable)
- Anatomy or disease that stops the IVUS catheter from passing
- Any reason not to have IVUS imaging, stent placement or balloon angioplasty
Read by machine on 13 November 2026.
Where in China
- The First Hospital of Jilin UniversityChangchun, ChinaContact: Mingyou Zhang, M.D.Taking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Jilin University
- Trial code
- NCT07853261
- Record updated
- 1 October 2026
- Original description
This is a prospective, single-center, single-arm exploratory observational study aiming to evaluate the impact of stepwise pressure-increasing non-compliant (NC) balloon post-dilation on stent expansion rate in patients undergoing single-stent implantation for coronary artery stenosis, with stent sizing guided by intravascular ultrasound-external elastic membrane (IVUS-EEM) measurement.Read full original descriptionShow less
Impact of Stepwise Pressure-Increasing NC Balloon Post-Dilation on Stent Expansion
This is a prospective, single-center, single-arm exploratory observational study aiming to evaluate the impact of stepwise pressure-increasing non-compliant (NC) balloon post-dilation on stent expansion rate in patients undergoing single-stent implantation for coronary artery stenosis, with stent sizing guided by intravascular ultrasound-external elastic membrane (IVUS-EEM) measurement.
A total of 150 eligible patients will be enrolled at The First Hospital of Jilin University. All participants will receive standard single-stent implantation followed by multi-stage stepwise pressure-increasing NC balloon post-dilation under IVUS monitoring. The post-dilation protocol includes sequential inflation at nominal pressure, rated burst pressure, and 24 atm, with IVUS assessment performed after each stage. All treatment procedures are conducted in accordance with routine clinical practice; no additional randomization or mandatory intervention is applied beyond the standard of care. The study solely observes and records outcomes associated with this treatment strategy.
Inclusion: Age ≥18 years regardless of gender; Coronary angiography confirms single-vessel coronary artery stenosis ≥50%, meeting the indication for single-stent implantation; Preoperative IVUS examination can clearly visualize the vessel EEM, allowing for stent size measurement and assessment of stent expansion-related parameters; The patient voluntarily participates in this study and signs the informed consent form; No contraindications related to IVUS examination, stent implantation, or balloon angioplasty.
Exclusion: Hemodynamically unstable; Presence of anatomical or pathological factors preventing IVUS catheter crossing.