Transcutaneous Auricular Vagus Nerve Stimulation for Chronic Tic Disorders/Tourette's Syndrome in Children and Adolescents
Key facts
- Where
- Hangzhou, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 6 and 18 years old?
Source: NCT07854665, who can take part
Where in China
- The first Affiliated Hospital of Zhejiang Chinese Medical University (FirstZhejiangCMU)Hangzhou, ChinaContact: Simeng Wang, PHDNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- The First Affiliated Hospital of Zhejiang Chinese Medical University
- Trial code
- NCT07854665
- Record updated
- 28 October 2026
- Original description
The objective of this trial is to evaluate the effect of transcutaneous auricular vagus nerve stimulation compared to sham stimulation in improving chronic tic disorder or Tourette's syndrome in children and adolescents.Read full original descriptionShow less
Transcutaneous Auricular Vagus Nerve Stimulation for Chronic Tic Disorders/Tourette's Syndrome in Children and Adolescents: A Randomized Controlled Clinical Trial
The objective of this trial is to evaluate the effect of transcutaneous auricular vagus nerve stimulation compared to sham stimulation in improving chronic tic disorder or Tourette's syndrome in children and adolescents.
Inclusion: Meets the DSM-5 diagnostic criteria for Tourette syndrome or chronic motor or vocal tic disorder; Age ≥6 and <18 years; YGTSS-TTS >15, or >10 for participants with motor tics or vocal tics only; If the participant is taking medication at enrollment, the medication regimen and dosage must have been stable for at least 4 weeks, with no planned changes in medication or dosage during the study; Has not received any non-pharmacological treatment for tics (e.g., acupuncture, transcranial magnetic stimulation, deep brain stimulation) within the preceding 8 weeks; Provides written informed consent.
Exclusion: Ear skin lesions, such as infection or eczema; An implanted cardiac pacemaker or other electronic medical device; Severe physical diseases, such as coronary heart disease, malignancy, or renal failure; Mental or cognitive disability that would preclude participation in the study; Current participation in another clinical trial.