A pain self-management programme for adults with joint damage from haemophilia
Tests a pain self-management programme in adults with haemophilia joint damage and chronic pain.
Plain-language title generated from the registry record
Registry title: Multicomponent Pain Self-Management in Adults With Haemophilic Arthropathy
Key facts
- Where
- Madrid, SpainSee the site
Where in Spain
- Spanish Federation of HaemophiliaMadrid, SpainNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Investigación en Hemofilia y Fisioterapia
- Trial code
- NCT07860632
- Record updated
- 6 October 2026
- Original description
Background: Haemophilic arthropathy is associated with chronic pain, functional limitation and impaired quality of life. Pain interference may also be influenced by cognitive, emotional and behavioural factors. Evidence for structured multicomponent pain self-management programmes specifically tailored to adults with haemophilic arthropathy remains limited.Read full original descriptionShow less
Multicomponent Pain Self-Management Programme in Adults With Haemophilic Arthropathy: Protocol for a Randomised Controlled Trial
Background: Haemophilic arthropathy is associated with chronic pain, functional limitation and impaired quality of life. Pain interference may also be influenced by cognitive, emotional and behavioural factors. Evidence for structured multicomponent pain self-management programmes specifically tailored to adults with haemophilic arthropathy remains limited.
Objective: To evaluate the effectiveness of a structured multicomponent pain self-management programme, compared with usual care, in reducing pain interference in adults with haemophilia A or B, haemophilic arthropathy and chronic pain.
Methods: Approximately 70 adults will be individually randomised in a 1:1 ratio to a multicomponent pain self-management programme or usual care. The intervention will comprise three 60-minute face-to-face group sessions delivered over approximately 6-8 weeks. The programme will integrate pain education, emotional-regulation training and cognitive-behavioural self-management strategies. Assessments will be performed at baseline, immediately after the intervention and at 6 months. The primary outcome will be the between-group difference in change in Brief Pain Inventory-Interference score from baseline to 6 months.
Inclusion: Age 18 years or older; Diagnosis of haemophilia A or B; Haemophilic arthropathy previously diagnosed and documented by the participant's haemophilia treatment centre; Persistent or recurrent pain for at least 3 months in one or more affected joints; Sufficient capacity to understand the programme content, follow study instructions and complete the assessment instruments; Ability to provide written informed consent; Sufficient understanding of Spanish to complete the study procedures and questionnaires.
Exclusion: Musculoskeletal surgery within the 2 months preceding inclusion; Concurrent participation in another structured educational or psychological intervention programme specifically targeting pain; Neurological or cognitive impairment that interferes with understanding of the intervention or completion of assessments; Acute bleeding episode or acute musculoskeletal event within the 4 weeks preceding baseline assessment that would preclude valid completion of the assessment; Insufficient understanding of Spanish to complete the study questionnaires.