Total Intravenous Versus Inhalational Anesthesia in Patients Undergoing Hip Fracture Surgery
Key facts
- Who runs it
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
- Where
- Türkiye1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Recruiting
- People taking part
- 110 people, planned
- Started
- 30 Sept 2026
- Expected to end
- 30 Mar 2027
- Type of study
- Observational, 2 groups
- Treatments tested
- Propofol-based Total Intravenous Anesthesia
- Sevoflurane-based Inhalational Anesthesia
- Record updated
- 13 October 2026
Who can take part
- Age
- 65 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 10 criteriaShow less
Who can take part
- Age 65 years or older
- ASA physical status I-III
- Scheduled to undergo elective or emergency hip fracture surgery under general anesthesia
- Provision of informed consent by the patient and/or legal representative
Who cannot take part
- Severe pre-existing neurological or psychiatric disorders, including advanced dementia or severe cognitive impairment preventing communication
- Known hypersensitivity or allergy to propofol or sevoflurane
- History of chronic heavy opioid or sedative substance use
- Refusal to participate in the study
- ASA physical status IV-V
- Inability to communicate in Turkish or to understand and complete the QoR-40 questionnaire
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
This prospective observational study aims to compare total intravenous anesthesia (TIVA) with sevoflurane-based inhalational anesthesia in patients aged 65 years and older undergoing hip fracture surgery under general anesthesia. The study will evaluate postoperative quality of recovery using the Quality of Recovery-40 (QoR-40) questionnaire and cognitive outcomes, including postoperative delirium and cognitive status. Pain scores, opioid consumption, recovery room stay, postoperative complications, and patient satisfaction will also be recorded. The anesthesia technique will be determined by the attending anesthesiologist as part of routine clinical practice, and the researchers will not interfere with the choice of anesthesia.
The 2 groups in the trial
- TIVA
Patients undergoing hip fracture surgery under general anesthesia who receive propofol-based total intravenous anesthesia (TIVA) as part of routine clinical care. The anesthesia technique is determined by the attending anesthesiologist, and the investigators do not interfere with treatment selection.
Treatment: Propofol-based Total Intravenous Anesthesia
- Sevoflurane
Patients undergoing hip fracture surgery under general anesthesia who receive sevoflurane-based inhalational anesthesia as part of routine clinical care. The anesthesia technique is determined by the attending anesthesiologist, and the investigators do not interfere with treatment selection.
Treatment: Sevoflurane-based Inhalational Anesthesia
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Effect of Total Intravenous Anesthesia Versus Inhalational Anesthesia on Postoperative Quality of Recovery and Cognitive Outcomes in Patients Undergoing Hip Fracture Surgery
- Record updated
- 13 October 2026