Furosemide After Delivery for Women With Severe Preeclampsia
Tests furosemide against placebo for blood pressure control in women after delivery.
Plain-language title generated from the registry record
Registry title: Role of Postpartum Furosemide in Recovery of Patients With Severe Preeclampsia
Key facts
- Where
- Peshawar, PakistanSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 45 years old?
Source: NCT07861685, who can take part
Where in Pakistan
- Lady Reading HospitalPeshawar, PakistanTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Lady Reading Hospital, Pakistan
- Trial code
- NCT07861685
- Record updated
- 6 October 2026
- Original description
This randomized controlled trial will compare oral furosemide with placebo for improving blood pressure control in women with severe preeclampsia after delivery. Participants will receive either 20 mg of furosemide or a placebo tablet once daily for 5 days, in addition to standard postpartum treatment for high blood pressure. Blood pressure, symptoms, adverse events, and the need for additional antihypertensive medication will be monitored for 7 days after delivery. The study will assess whether adding furosemide helps achieve better postpartum blood pressure control compared with placebo.Read full original descriptionShow less
Efficacy of Postpartum Furosemide in Patients With Severe Preeclampsia: A Randomized Controlled Trial
This randomized controlled trial will compare oral furosemide with placebo for improving blood pressure control in women with severe preeclampsia after delivery. Participants will receive either 20 mg of furosemide or a placebo tablet once daily for 5 days, in addition to standard postpartum treatment for high blood pressure. Blood pressure, symptoms, adverse events, and the need for additional antihypertensive medication will be monitored for 7 days after delivery. The study will assess whether adding furosemide helps achieve better postpartum blood pressure control compared with placebo.
Inclusion: Women aged 18 to 45 years; Any parity; Gestational age >28 weeks based on LMP; Severe preeclampsia as per the study operational definition.
Exclusion: History of allergy to furosemide or prior use of diuretics before randomization; History of underlying cardiac disease during pregnancy or postpartum; Known rheumatologic disease or advanced diabetes; History of thyroid disorders or other medical illnesses that may interfere with blood pressure management; Pre-existing renal dysfunction or serum creatinine >1.2 mg/dL on medical record; Significant hypokalemia (K <3 mEq/L) before enrollment.