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How Temperature and Humidity Affect Breathing in Children and Teens With and Without Asthma

Tests how heat, cold and humidity affect breathing in young people with asthma.

Plain-language title generated from the registry record
Registry title: Testing the Effects of Temperature & Humidity on Children With and Without Asthma in an Environmental Climatic Chamber

Key facts

Where
Oshawa, CanadaSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 11 and 18 years old?

Source: NCT07864506, who can take part

Where in Canada

  • Ontario Tech UniversityOshawa, CanadaNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
University of Ontario Institute of Technology
Trial code
NCT07864506
Record updated
7 October 2026
Original description
The goal of this clinical study is to learn how different temperature and humidity conditions affect breathing, lung function, exercise capacity, symptoms, and other physical responses in children and youth aged 11 to 18 years with asthma, compared with age- and sex-matched children and youth without asthma.Read full original descriptionShow less

Testing the Effects of Temperature & Humidity on Children With and Without Asthmas in an Environmental Climatic Chamber

The goal of this clinical study is to learn how different temperature and humidity conditions affect breathing, lung function, exercise capacity, symptoms, and other physical responses in children and youth aged 11 to 18 years with asthma, compared with age- and sex-matched children and youth without asthma.

The main questions it aims to answer are:

* How do different temperature and humidity conditions affect lung function, breathing symptoms, exercise capacity, and physiological responses in children and youth with asthma? * Do children and youth with asthma respond differently to these environmental conditions than children and youth without asthma? * Do sex and gender influence these responses?

Researchers will compare children and youth with asthma to age- and sex-matched children and youth without asthma to see if temperature and humidity exposures have different effects on breathing, exercise performance, symptoms, and physiological responses.

Participants will:

* Attend two study visits in a climate-controlled chamber. * Be exposed to hot, cold, and varying humidity conditions for short periods of time. * Complete breathing tests and exercise testing before, during, and after each exposure. * Have symptoms, physical activity, and physiological responses monitored throughout the study.

Inclusion: Children and youth aged 11 to 18 years; Able to provide assent/consent, with parent or guardian consent when required; Diagnosed with asthma and currently stable (for the asthma group); Willing to attend study visits at the ACE research facility in Oshawa, Ontario; For the control group: No asthma or other respiratory condition.

Exclusion: Does not meet all inclusion criteria; Parent or guardian does not provide consent when required.

ClinicalTrials.gov NCT07864506