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Links Between Blood Inflammation Markers and Pain in Adults With Sickle Cell Disease

Looks at how inflammation markers relate to pain in adults with sickle cell disease.

Plain-language title generated from the registry record
Registry title: Inflammatory Markers and Pain in Sickle Cell Disease

Key facts

Where
Asyut, EgyptSee the site

Where in Egypt

  • Assiut university HospitalsAsyut, EgyptNo longer taking part

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Trial details

Who runs it
Assiut University
Trial code
NCT07865039
Record updated
8 October 2026
Original description
This observational cross-sectional study aims to assess the relationship between inflammatory markers and pain intensity in adult patients with sickle cell disease. The study will evaluate inflammatory markers in patients with different clinical presentations, including steady state and vaso-occlusive crisis.Read full original descriptionShow less

Association Between Inflammatory Markers and Pain Intensity in Patients With Sickle Cell Disease

This observational cross-sectional study aims to assess the relationship between inflammatory markers and pain intensity in adult patients with sickle cell disease. The study will evaluate inflammatory markers in patients with different clinical presentations, including steady state and vaso-occlusive crisis.

Inclusion: Adults aged ≥18 years. Confirmed diagnosis of sickle cell disease. Patients attending or admitted to the Internal Medicine Department during the study period; Willingness to participate and provide informed consent.

Exclusion: Patients younger than 18 years. Acute infection or sepsis Autoimmune or chronic inflammatory diseases. Malignancy End-stage renal disease on dialysis. Chronic liver disease Blood transfusion within the preceding four weeks Recent surgery or trauma (within the preceding four weeks. Refusal to participate.

ClinicalTrials.gov NCT07865039