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Testing an adaptive proton therapy workflow for oropharyngeal cancer

Studies a computer-based way to adjust proton radiation plans for oropharyngeal cancer.

Plain-language title generated from the registry record
Registry title: Off-line Adaptive Proton Therapy

Key facts

Where
Groningen, NetherlandsSee the site

Where in Netherlands

  • University Medical Center GroningenGroningen, NetherlandsNo longer taking part

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  4. What happens if I want to stop?
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Trial details

Who runs it
University Medical Center Groningen
Trial code
NCT07866547
Record updated
8 October 2026
Original description
This prospective in-silico study evaluates a novel Off-line Adaptive Proton Therapy (o-APT) workflow for patients with oropharyngeal cancer receiving proton therapy. The study assesses whether automated image analysis, treatment plan adaptation, and quality assurance can identify and prepare treatment plan modifications more efficiently than current clinical practice, without affecting patient care.Read full original descriptionShow less

Off-line Adaptive Proton Therapy

This prospective in-silico study evaluates a novel Off-line Adaptive Proton Therapy (o-APT) workflow for patients with oropharyngeal cancer receiving proton therapy. The study assesses whether automated image analysis, treatment plan adaptation, and quality assurance can identify and prepare treatment plan modifications more efficiently than current clinical practice, without affecting patient care.

Inclusion: Oropharyngeal cancer patients; Planned for curatively intended proton therapy; Treated with definitive radiotherapy, chemoradiation, or bioradiation; Provided informed consent according to Standard Follow-up Program (SFP) for using data for research.

Exclusion: None.

ClinicalTrials.gov NCT07866547