Under construction – not a live service
Sign in
Not yet taking people in United StatesNo phase

Tests an emergency department outreach program for opioid overdose and HIV prevention

Tests a care coordination program for adults at risk of overdose or HIV.

Plain-language title generated from the registry record
Registry title: Prevention and Rapid Outreach for Treatment, Engagement, and Care Transition From the Emergency Department

Key facts

Where
Baltimore, United StatesSee the site

Where in United States

  • The Johns Hopkins Hospital Emergency DepartmentBaltimore, United StatesNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Johns Hopkins University
Trial code
NCT07868393
Record updated
5 November 2026
Original description
The Prevention and Rapid Outreach for Treatment, Engagement, and Care Transition from the Emergency Department (PROTECT-ED) study evaluates an emergency department-based implementation strategy designed to improve delivery of evidence-based overdose and HIV prevention services during community re-entry.Read full original descriptionShow less

Prevention and Rapid Outreach for Treatment, Engagement, and Care Transition From the Emergency Department (PROTECT-ED)

The Prevention and Rapid Outreach for Treatment, Engagement, and Care Transition from the Emergency Department (PROTECT-ED) study evaluates an emergency department-based implementation strategy designed to improve delivery of evidence-based overdose and HIV prevention services during community re-entry.

Inclusion: Are 18 years of age or older; Present to the Johns Hopkins Hospital Emergency Department; Have been released within the previous 180 days from a prison, jail, juvenile detention facility, immigration detention facility, halfway house, residential reentry center, or other correctional setting. Recent incarceration may be confirmed through participant self-report, electronic medical record documentation, the Victim Information and Notification Everyday (VINE) system, or other available documentation. Participant self-report alone is sufficient to establish eligibility; Meet criteria for opioid use disorder or hazardous opioid use and are considered appropriate for evaluation for medications for opioid use disorder (MOUD) or are at risk for HIV acquisition; Able to speak and understand communicate in English sufficiently to provide informed consent and complete study assessments; Provide informed consent; Have a reliable telephone number for study follow-up.

Exclusion: Prior enrollment in the PROTECT-ED study; Inability to provide informed consent during the index emergency department encounter; Lack of a reliable telephone number for study follow-up.

ClinicalTrials.gov NCT07868393