Lifestyle Factors Behind Blood Sugar Swings After Eating, in Prediabetes and Type 2 Diabetes
Looks at what predicts blood sugar changes after meals in adults with different glycemic status.
Plain-language title generated from the registry record
Registry title: LIfestyle MEtabotype Study A
Key facts
- Where
- Potsdam, GermanySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 75 years old?
Source: NCT07868601, who can take part
Where in Germany
- German Institute of Human Nutrition, Dept. Molecular Metabolism and Precision Nutrition and Decision Neuroscience and NutritionPotsdam, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- German Institute of Human Nutrition
- Trial code
- NCT07868601
- Record updated
- 9 October 2026
- Original description
Glycemic responses vary significantly among individuals, even when consuming identical foods or meals, but the factors predicting individual glucose response to food intake remain poorly investigated.Read full original descriptionShow less
LIfestyle MEtabotype Study (Module A)
Glycemic responses vary significantly among individuals, even when consuming identical foods or meals, but the factors predicting individual glucose response to food intake remain poorly investigated.
The aim of the LIfestyle MEtabotype study (LIME) observational study is to identify lifestyle-related and mechanistic factors which predict individual postprandial glucose fluctuations in individuals with different glycemic status (prediabetes, type 2 diabetes [T2D], and absence of prediabetes or T2D). To address this aim, the study will conduct a comprehensive lifestyle characterization and metabolic, molecular and neurocognitive phenotyping during study center visits and a dietary, glucose, sleep and activity monitoring during the observational phase.
Inclusion: Overweight or obesity (BMI 25-40 kg/m²); Good knowledge of German.
Exclusion: Travel across more than one time zone in the last month before and during study participation; Existing or past hematological malignancies, other malignant tumors, unless successfully treated more than 12 months before study start; Use of illicit or legal drugs one week prior to study start and during study participation; Diabetes treatment with insulin or sulfonylureas or diabetes medication in the absence of manifest type 2 diabetes; Medications affecting nutrient absorption; Medications with immunosuppressants or steroids (oral or parenteral); Intermittent fasting or calorie-restricted diet four weeks prior to the start of the study or during the study; Ketogenic diet or ketogenic supplements four weeks prior to or during module B; Electrical implants or non-removable metallic implants; Concurrent participation in another intervention study; Severe renal, liver or heart disease; Severe neurological or psychiatric disorders; Known systemic infections; Type 1 diabetes and rare forms of diabetes; Blood coagulation disorders or anticoagulation therapy that cannot be interrupted; Current eating disorders, functional or structural digestive disorders or bariatric surgery; Food allergies or intolerances to ingredients of the test meals; Weight changes of more than 5% in the last 3 months; Night shift work; Intensive regular physical activity of more than 2 hours per day; Current pregnancy or breastfeeding; Daily alcohol consumption of more than 20 grams or more than 150 grams per week; Unstable thyroid dysfunction; Left-handedness; Severe claustrophobia; Assessment by the study physician based on medical concerns precluding study participation.