Functional Capacity Differences in Knee Osteoarthritis With Similar Pain Severity
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Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 75 years old?
Source: NCT07869680, who can take part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Mardin Artuklu University
- Trial code
- NCT07869680
- Record updated
- 9 October 2026
- Original description
People with knee osteoarthritis may have similar levels of pain but very different abilities to walk, rise from a chair, and perform daily activities. This study aims to examine the factors associated with these differences in functional capacity among patients with similar knee pain severity.Read full original descriptionShow less
Evaluation of Functional Capacity Heterogeneity in Patients With Knee Osteoarthritis and Similar Pain Severity
People with knee osteoarthritis may have similar levels of pain but very different abilities to walk, rise from a chair, and perform daily activities. This study aims to examine the factors associated with these differences in functional capacity among patients with similar knee pain severity.
Adults with radiographic knee osteoarthritis and an average knee pain level of 4-6 on a 0-10 scale will be included. During a single study visit, participants will complete questionnaires about physical function, central sensitization-related symptoms, and physical activity. They will also perform a 10-meter walk test, a 30-second chair stand test, and the Timed Up and Go test.
Self-reported physical function will be assessed using the function subscale of the Western Ontario and McMaster Universities Osteoarthritis Index. Participants with better and poorer function will be compared, and the clinical factors independently associated with functional capacity will be examined. No treatment or intervention will be assigned as part of this study.
Inclusion: Age 40-75 years; Clinical and radiographic diagnosis of knee osteoarthritis; Kellgren-Lawrence grade 2 or 3 knee osteoarthritis; Knee pain lasting at least 3 months; Average knee pain intensity during the previous week between 4 and 6 on a 0-10 visual analog scale; Ability to provide written informed consent.
Exclusion: History of knee surgery or intra-articular knee injection within the previous 6 months; Inflammatory rheumatic disease; Neurological disease that substantially affects knee function; Severe cardiopulmonary disease that prevents walking or performance testing; Cognitive impairment that prevents participation in the assessment procedures; Kellgren-Lawrence grade 1 or 4 knee osteoarthritis; For participants with bilateral knee osteoarthritis, assessments will be performed on the more painful knee.