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Comparing two ventilator settings in obese people having keyhole abdominal surgery

Compares two breathing machine modes in obese adults having laparoscopic surgery.

Key facts

Who runs it
Kocaeli University
Where
Kocaeli, TürkiyeSee the site
Trial code
Registry title
VC-AF vs FCV in Obese Patients Undergoing Laparoscopic Surgery
Status
Recruiting
People taking part
78 people, planned
Started
21 Sept 2026
Expected to end
21 Sept 2027
Type of study
Observational, 2 groups
Record updated
15 October 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with obesity who are scheduled for planned laparoscopic (keyhole) surgery under general anesthesia. It compares two ways of ventilating the lungs during the operation.

Age
18 to 65 years
Sex
All sexes can join.
Disease stage
Body mass index (BMI) of 30 kg/m² or higher; ASA Physical Status I-III; elective laparoscopic surgery under general anesthesia.

Main reasons for not taking part

  • Pregnancy
  • Emergency surgery
  • A cardiac pacemaker
  • Chronic obstructive pulmonary disease (COPD)

The registry criteria, word for word

Show all 2 criteriaShow less

Who can take part

  • Age ≥18 years Body mass index (BMI) ≥30 kg/m² American Society of Anesthesiologists (ASA) Physical Status I-III Scheduled to undergo elective laparoscopic surgery under general anesthesia

Who cannot take part

  • Pregnancy Emergency surgery Presence of a cardiac pacemaker Chronic obstructive pulmonary disease (COPD)

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 65 years old?

Where in Türkiye

  • Kocaeli University Faculty of MedicineKocaeli, TürkiyeContact: Elif Balcı Koç, MDTaking people

About the trial

What the trial wants to find out

Obesity adversely affects respiratory physiology by reducing lung volumes and compliance and increasing airway resistance and alveolar collapse. These effects are further aggravated by pneumoperitoneum during laparoscopic surgery, increasing the risk of impaired oxygenation and ventilator-induced lung injury (VILI).

Read full original descriptionShow less

Mechanical power (MP) reflects the total energy transferred to the respiratory system during mechanical ventilation and is influenced by tidal volume, respiratory rate, airway pressures, flow, and PEEP. Increased airway and driving pressures may contribute to higher mechanical power and lung injury, particularly in obese patients undergoing laparoscopic surgery.

This study aims to compare flow-controlled ventilation (FCV) and volume-controlled ventilation with autoflow (VC-AF) in obese patients undergoing laparoscopic surgery in terms of airway pressures, driving pressure, and mechanical power. The investigators hypothesize that FCV may reduce airway pressures, driving pressure, and mechanical power compared with VC-AF, potentially decreasing the risk of VILI. The effect of FCV on oxygenation will also be evaluated as a secondary outcome.

The 2 groups in the trial

  • Flow-Controlled Ventilation (FCV)
  • Volume-Controlled Ventilation (VCV)

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Comparison of VC-AF and FCV Mechanical Ventilation Modes in Obese Patients Undergoing Laparoscopic Surgery
Plain-language title
Comparing two ventilator settings in obese people having keyhole abdominal surgeryGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Fit questions
Built from NCT07875530, who can take part
Record updated
15 October 2026