Clinical Importance of Occult Suprapatellar Effusion in Knee Osteoarthritis
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Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 80 years old?
Source: NCT07876752, who can take part
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- How often do I need to come in, and for how long each time?
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Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Mardin Artuklu University
- Trial code
- NCT07876752
- Record updated
- 20 October 2026
- Original description
Small amounts of fluid in the knee joint may not always be visible during a standard ultrasound examination performed while the leg is relaxed. When the quadriceps muscle contracts, this fluid may move into the area above the kneecap and become visible. This finding is referred to in this study as occult suprapatellar effusion.Read full original descriptionShow less
Small amounts of fluid in the knee joint may not always be visible during a standard ultrasound examination performed while the leg is relaxed. When the quadriceps muscle contracts, this fluid may move into the area above the kneecap and become visible. This finding is referred to in this study as occult suprapatellar effusion.
The aim of this study is to determine whether occult suprapatellar effusion is associated with knee pain and physical function in people with knee osteoarthritis. Participants will undergo ultrasound examination first at rest and then during quadriceps contraction. Based on these findings, they will be classified as having effusion visible at rest, occult effusion visible only during muscle contraction, or no effusion in either condition.
Knee pain, self-reported symptoms and function, and chair stand performance will be compared among these groups. The study will also examine whether greater effusion depth is associated with more severe pain, greater functional limitation, and poorer physical performance. No treatment will be assigned as part of the study.
Inclusion: Age 40-80 years; Clinical diagnosis of primary knee osteoarthritis and radiographic Kellgren-Lawrence grade 2, 3, or 4; Pain in the knee to be evaluated; Ability to perform voluntary quadriceps contraction and the 30-second chair stand test; Provision of written informed consent.
Exclusion: Intra-articular injection into the evaluated knee within the previous 3 months; Knee trauma within the previous 3 months; Inflammatory rheumatic disease, crystal arthropathy, or active joint infection; History of major surgery on the evaluated knee; Neurological, cardiopulmonary, or other musculoskeletal disease that may substantially affect chair stand performance; Marked varus or valgus deformity; Inability to perform adequate voluntary quadriceps contraction; Pregnancy.