Brain Wave Patterns During Anesthesia in People With Obesity
Compares frontal brain wave recordings during general anesthesia in adults with obesity and normal weight.
Plain-language title generated from the registry record
Registry title: Frontal EEG Dynamics During Anesthesia in Patients With Obesity and Normal Weight
Key facts
- Where
- Düzce, TürkiyeSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults having planned surgery under general anesthesia with propofol. Some have obesity and some have normal weight. Their brain activity is recorded during anesthesia.
- Age
- 18-65 years
- Sex
- All sexes can join.
- Disease stage
- Obesity group: BMI 30 or above. Normal-weight group: BMI 18.5-24.9. ASA physical status I-III.
Main reasons for not taking part
- BMI 25.0-29.9
- History of epilepsy or seizures
- Known major brain or nerve disease that may affect EEG
- Regular use of antiepileptic or other drugs that strongly affect EEG
- Emergency surgery or pregnancy
Read by machine on 13 November 2026.
Where in Türkiye
- Düzce University Research and Application HospitalDüzce, TürkiyeContact: gizem demir şenoğluTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Duzce University
- Trial code
- NCT07877090
- Record updated
- 22 October 2026
- Original description
This prospective observational study aims to compare frontal electroencephalographic (EEG) spectral dynamics between patients with obesity and normal weight undergoing general anesthesia. The primary objective is to evaluate whether changes in frontal alpha power around propofol-induced loss of consciousness differ between the two BMI groups. Secondary objectives include comparing changes in delta power, the alpha/delta power ratio, and frontal alpha asymmetry around loss of consciousness, as well as evaluating EEG spectral dynamics throughout the intraoperative period. Anesthetic management will be determined by the attending anesthesiologist according to routine clinical practice, without intervention by the study investigators.Read full original descriptionShow less
Frontal EEG Spectral Dynamics During General Anesthesia in Obese and Normal-Weight Patients: A Prospective Observational Study
This prospective observational study aims to compare frontal electroencephalographic (EEG) spectral dynamics between patients with obesity and normal weight undergoing general anesthesia. The primary objective is to evaluate whether changes in frontal alpha power around propofol-induced loss of consciousness differ between the two BMI groups. Secondary objectives include comparing changes in delta power, the alpha/delta power ratio, and frontal alpha asymmetry around loss of consciousness, as well as evaluating EEG spectral dynamics throughout the intraoperative period. Anesthetic management will be determined by the attending anesthesiologist according to routine clinical practice, without intervention by the study investigators.
Inclusion: Adults aged 18-65 years; Scheduled for elective surgery under general anesthesia; American Society of Anesthesiologists (ASA) physical status I-III; General anesthesia induction performed with propofol; Availability of continuous frontal EEG monitoring (SedLine) during anesthesia; BMI 18.5-24.9 kg/m² for the normal-weight group or BMI ≥30 kg/m² for the obesity group; Ability to provide written informed consent.
Exclusion: Regular use of antiepileptic medications or other drugs known to substantially affect EEG activity; Emergency surgery; History of epilepsy or seizure disorder; Known major neurological disease that may affect EEG activity; Skin lesions, infection, or other conditions of the forehead preventing appropriate placement of the EEG sensor; Inability to obtain an adequate-quality EEG recording because of technical failure or excessive artifacts; - BMI 25.0-29.9 kg/m²; Altered level of consciousness before anesthesia; Pregnancy; Requirement for substantial deviation from the planned routine anesthetic management that prevents standardized EEG assessment; Refusal to participate or inability to provide written informed consent.