Balance training with thinking tasks for people with multiple sclerosis
Tests whether balance training combined with thinking tasks is feasible in adults with multiple sclerosis.
Plain-language title generated from the registry record
Registry title: Dual-Task Balance Training in People With Multiple Sclerosis: a Randomized Feasibility Study
Key facts
- Where
- Verona, ItalySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT07878702, who can take part
Where in Italy
- Policlinico GB Rossi - University Hospital Borgo RomaVerona, ItalyNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Universita di Verona
- Trial code
- NCT07878702
- Record updated
- 16 October 2026
- Original description
The goal of this randomized controlled feasibility study is to assess whether a balance training program that includes dual-task exercises is feasible in people with multiple sclerosis (MS). The study also aims to obtain preliminary data on the effects of the training on walking under dual-task conditions and on brain activity recorded with a wearable EEG. The main questions it aims to answer are:Read full original descriptionShow less
Neural Correlates of Motor-cognitive Interaction During Walking in People With Multiple Sclerosis: a Cross-sectional and a Feasibility Study of a Dual-task Rehabilitation Intervention
The goal of this randomized controlled feasibility study is to assess whether a balance training program that includes dual-task exercises is feasible in people with multiple sclerosis (MS). The study also aims to obtain preliminary data on the effects of the training on walking under dual-task conditions and on brain activity recorded with a wearable EEG. The main questions it aims to answer are:
* Is the training feasible in terms of recruitment, retention, adherence, data completeness, and assessment burden? * What are the preliminary effects of the training on dual-task costs during the Timed Up and Go test (TUG) and the 2-Minute Walk Test (2MWT), on prefrontal activation and mental workload during walking, and on clinical outcomes?
Researchers will compare participants who receive the training with participants who receive no additional rehabilitation during the study period.
Participants will:
* receive 14 in-hospital sessions of balance and dual-task training (60 minutes, 2 sessions per week, about 7 weeks) if allocated to the intervention group, or no new rehabilitation if allocated to the control group; * perform a dual-task walking assessment (TUG, 2MWT, backward digit span) while wearing an 8-channel wearable EEG headset and 3 inertial sensors, before (T0) and after (T1) the study period; * complete clinical scales and questionnaires on balance, gait, cognition, fatigue, mood, pain, and quality of life.
Inclusion: Age 18 to 75 years; Diagnosis of multiple sclerosis (relapsing-remitting, primary progressive or secondary progressive); Timed Up and Go test > 8.4 s; Expanded Disability Status Scale (EDSS) score < 7; Able to walk independently for 2 minutes; Written informed consent.
Exclusion: Other conditions that may affect motor function; Cognitive impairment (Mini-Mental State Examination score < 24); Severe visual deficits.