A Mobile App for Mood, Routines and Medication in Severe Mental Illness
Tests the MoodSync app in adults with severe mental illness, alongside usual care.
Plain-language title generated from the registry record
Registry title: A Mobile App to Support Mood, Daily Routines and Medication Adherence in Adults With Severe Mental Illness
Key facts
- Where
- Manama, BahrainSee the site
Where in Bahrain
- Psychiatric Hospital, Government HospitalsManama, BahrainNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Alexandria University
- Trial code
- NCT07879131
- Record updated
- 16 October 2026
- Original description
The goal of this clinical trial is to learn whether MoodSync, a mobile application for patients and their family caregivers, improves mood stability, medication adherence, daily functioning and early detection of relapse warning signs in adults with severe mental illness in Bahrain. The main question it aims to answer is: Does MoodSync plus standard care improve manic symptoms, medication adherence, practical and social functioning, and early warning signs more than standard care alone?Read full original descriptionShow less
Effectiveness of MoodSync: A Just-in-Time Dual Mobile Application for Mood Monitoring, Social Rhythm Regulation, Medication Adherence, and Relapse Prevention Among Patients With Severe Mental Illness: A Randomized Controlled Trial
The goal of this clinical trial is to learn whether MoodSync, a mobile application for patients and their family caregivers, improves mood stability, medication adherence, daily functioning and early detection of relapse warning signs in adults with severe mental illness in Bahrain. The main question it aims to answer is: Does MoodSync plus standard care improve manic symptoms, medication adherence, practical and social functioning, and early warning signs more than standard care alone?
Participants will be randomly assigned to MoodSync plus standard care or standard care alone. MoodSync participants will use the patient app for 12 weeks for daily mood check-ins, sleep and activity tracking with a wearable device, medication reminders, daily-routine (social rhythm) support and early warning-sign reporting. A nominated family caregiver may use the linked caregiver app. All participants continue standard care and complete questionnaires before and after the intervention period.
Research hypothesis:
* Patients who use MoodSync will show greater improvement in mood symptoms, medication adherence, practical and social functioning, and relapse-related outcomes than patients receiving standard care alone.
Inclusion: Adults aged 18 years or older; Diagnosis of a severe mental illness (bipolar I or II disorder, schizophrenia, schizoaffective disorder, or major depressive disorder) according to DSM-5-TR, confirmed by the treating psychiatrist; Clinically stable, defined as no psychiatric hospital admission in the previous 3 months; Receiving care at a participating mental health service; Able to use a smartphone application; Able to provide written informed consent.
Exclusion: Acute psychiatric crisis at the time of recruitment; Severe cognitive impairment preventing use of the application; Inability to provide informed consent; No access to a compatible mobile device, unless one is provided by the project; Family caregivers (intervention group, optional): adult family member nominated by the participant, who gives separate written informed consent.