Eloralintide and tirzepatide combined for weight loss in adults with obesity
Tests eloralintide with tirzepatide for weight loss in adults with obesity.
Plain-language title generated from the registry record
Registry title: A Study of EloraTZP in Adult Participants With Obesity Without Type 2 Diabetes
Key facts
- Where
- Ansan-si, Busan, Guri-si, Gwangju, Gyeongsan-si, Junggu, Namdong-gu, Seogu, Seongnam, Seongnam-si, and Seoul, South KoreaSee the 13 sites
- Phase
- Phase 3
Where in South Korea
- Korea University Ansan HospitalAnsan-si, South KoreaNo longer taking part
- Pusan National University Yangsan HospitalBusan, South KoreaNo longer taking part
- Hanyang University Guri HospitalGuri-si, South KoreaNo longer taking part
- Chosun University HospitalGwangju, South KoreaNo longer taking part
- Yeungnam Univeristy Medical CenterGyeongsan-si, South KoreaNo longer taking part
- Kyungpook National University HospitalJunggu, South KoreaNo longer taking part
- Gachon University Gil Medical CenterNamdong-gu, South KoreaNo longer taking part
- Konyang University HospitalSeogu, South KoreaNo longer taking part
- Seoul National University Bundang HospitalSeongnam, South KoreaNo longer taking part
- CHA Bundang Medical Center, CHA UniversitySeongnam-si, South KoreaNo longer taking part
- Nowon Eulji Medical Center, Eulji UniversitySeoul, South KoreaNo longer taking part
- Seoul National University HospitalSeoul, South KoreaNo longer taking part
- Severance Hospital, Yonsei University Health SystemSeoul, South KoreaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Eli Lilly and Company
- Trial code
- NCT07881432EU 2026-526047-34-00
- Record updated
- 3 November 2026
- Original description
The purpose of this study is to investigate the efficacy and safety of eloralintide and tirzepatide coformulation (EloraTZP) compared with tirzepatide, eloralintide and placebo for body weight reduction in participants with obesity.Read full original descriptionShow less
A Phase 3 Study to Investigate the Efficacy and Safety of LY900043 in Adult Participants With Obesity Without Type 2 Diabetes
The purpose of this study is to investigate the efficacy and safety of eloralintide and tirzepatide coformulation (EloraTZP) compared with tirzepatide, eloralintide and placebo for body weight reduction in participants with obesity.
Participation in the study will last about 2 years.
Inclusion: Have a stable self-reported body weight (<5% body weight change) for 90 days prior to screening; Have a BMI of ≥35 kg/m2 at screening; Have a history of at least 1 self-reported unsuccessful dietary effort to reduce body weight.
Exclusion: Have a prior or planned surgical treatment for obesity (liposuction, cryolipolysis, or abdominoplasty allowed if performed >1 year before screening); Have a prior or planned endoscopic procedure and/or device-based therapy for obesity and/or type 2 diabetes (prior device-based therapy acceptable if device removal was more than 6 months prior to screening); Have had within 90 days prior to screening:; heart attack; stroke; coronary artery revascularization; unstable angina, or; hospitalization due to congestive heart failure; Have taken medications or alternative remedies intended for weight loss within 90 days of screening; Have type 1 diabetes, type 2 diabetes, or any other type of diabetes; Have a history or diagnosis of New York Heart Association Functional Classification Class IV congestive heart failure; Have taken any glucose-lowering medication within 90 days of screening.