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NCT07882303Not yet recruiting

Native T1 Mapping and ECV in Chronic Hemolytic Anemia

The Added Value of Native T1 Mapping and Extracellular Volume Calculation in the Detection of Myocardial Iron Overload and Fibrosis in Patients With Chronic Hemolytic Anemias

Source: ClinicalTrials.gov · Last updated 20 Oct 2026

Brief summary (registry, in English)

This cross-sectional study aims to evaluate the diagnostic performance of native T1 mapping and extracellular volume fraction for the detection of myocardial iron overload and fibrosis in patients with chronic hemolytic anemia compared with T2\* relaxometry.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
54 (estimated)
First submitted
13 Oct 2026
Start date
20 Oct 2026
Primary completion date
20 Oct 2027
Lead sponsor
Assiut University
Diseases
Thalassaemia
NCT number
NCT07882303

What you commit to

  • Study type: Observational
  • Planned participants: 54
  • From 20 Oct 2026 to the primary completion date, 20 Oct 2027
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Unrelated cardiovascular disease or prior cardiac surgery

Other illness

  • Non-diagnostic cardiac magnetic resonance
  • Non-transfusional cause of cardiac iron overload

Other

  • \- MRI contraindication
  • Gadolinium contraindication (native sequences still performed)
  • Refusal of informed consent

Who the study is looking for

  • \- Confirmed transfusion-dependent chronic hemolytic anemia
  • Age 7 years or older
  • Able to cooperate with cardiac magnetic resonance without anesthesia
  • Written informed consent

Age in the registry: 7 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.