Predicting Recovery After Bleeding Stroke Caused by Spontaneous Intracerebral Haemorrhage
Follows adults after intracerebral haemorrhage to learn how well they recover.
Plain-language title generated from the registry record
Registry title: Outcome Prediction and Recovery After Spontaneous Intracerebral Haemorrhage
Key facts
- Where
- Maribor, SloveniaSee the site
Where in Slovenia
- University Medical Centre Maribor, Department of NeurologyMaribor, SloveniaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Medical Centre Maribor
- Trial code
- NCT07882784
- Record updated
- 20 October 2026
- Original description
Spontaneous intracerebral haemorrhage (ICH) is a severe form of stroke with high mortality and frequent long-term disability. Current tools to predict how an individual patient will recover are limited.Read full original descriptionShow less
CrossReg-4-Health: A Multicentre Prospective Cohort Study of Outcome Prediction and Recovery After Spontaneous Intracerebral Haemorrhage
Spontaneous intracerebral haemorrhage (ICH) is a severe form of stroke with high mortality and frequent long-term disability. Current tools to predict how an individual patient will recover are limited.
CrossReg-4-Health is a prospective, multicentre observational cohort study that will enrol 300 consecutive adults with acute spontaneous ICH at three hospitals in Slovenia and Austria. During hospitalisation, the study will collect clinical data, standardised neurological and pain assessments, routine laboratory results, CT, CT angiography and MRI findings, and two research blood samples for biomarkers of brain injury, inflammation, coagulation and pain. Participants will be followed up at 6 and 12 months for survival, functional outcome, neurological status, pain, health-related quality of life, rehabilitation use and readmissions.
The main aim is to develop a multimodal prognostic model for functional outcome (modified Rankin Scale) 12 months after ICH.
Inclusion: Age 18 years or older; Acute spontaneous (non-traumatic) intracerebral haemorrhage confirmed by non-contrast CT or MRI; Admission during the acute phase of haemorrhage to one of the participating centres; Written informed consent from the patient or, if the patient lacks capacity, consent from a legally authorised representative.
Exclusion: Intracerebral haemorrhage secondary to head trauma; Haemorrhage due to an intracranial neoplasm; Isolated subarachnoid haemorrhage or another primary type of intracranial haemorrhage; Expected survival of less than 24 hours due to non-neurological comorbidity; End-of-life care decision already made at presentation; Withdrawal of consent or major protocol violation.