Fish extract and turmeric supplement for people with active lung tuberculosis
Tests a Channa striata and Curcuma supplement in adults with active pulmonary tuberculosis.
Plain-language title generated from the registry record
Registry title: Channa Striata and Curcuma Domestica Supplementation in Patients With Active Pulmonary Tuberculosis
Key facts
- Where
- Medan, IndonesiaSee the site
Where in Indonesia
- Nutrition Department, Universitas Sumatera Utara, Medan, IndonesiaMedan, IndonesiaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- DINA KEUMALA SARI
- Trial code
- NCT07887724
- Record updated
- 21 October 2026
- Original description
This study aims to evaluate the effect of combined supplementation with Channa striata extract and Curcuma domestica rhizome on nutritional status, inflammatory markers, and quality of life in patients with active pulmonary tuberculosis receiving standard anti tuberculosis treatment at public health centers in Medan City. Pulmonary tuberculosis is frequently accompanied by malnutrition, persistent systemic inflammation, and impaired quality of life, all of which can delay recovery and worsen clinical outcomes. Channa striata is a rich source of high quality protein and albumin that may support nutritional recovery, while Curcuma domestica contains curcumin with well documented anti inflammatory properties. This study will assess whether the combined supplementation provides additional benefits in improving nutritional status, reducing inflammatory markers, and enhancing health related quality of life compared with standard treatment alone. The findings are expected to provide evidence for a safe, affordable, and locally available nutritional intervention that may complement conventional tuberculosis management.Read full original descriptionShow less
The Effect of Combined Supplementation With Channa Striata and Curcuma Domestica Rhizome on Nutritional Status, Inflammatory Markers, and Quality of Life in Patients With Active Pulmonary TB at the Medan City Public Health Center
This study aims to evaluate the effect of combined supplementation with Channa striata extract and Curcuma domestica rhizome on nutritional status, inflammatory markers, and quality of life in patients with active pulmonary tuberculosis receiving standard anti tuberculosis treatment at public health centers in Medan City. Pulmonary tuberculosis is frequently accompanied by malnutrition, persistent systemic inflammation, and impaired quality of life, all of which can delay recovery and worsen clinical outcomes. Channa striata is a rich source of high quality protein and albumin that may support nutritional recovery, while Curcuma domestica contains curcumin with well documented anti inflammatory properties. This study will assess whether the combined supplementation provides additional benefits in improving nutritional status, reducing inflammatory markers, and enhancing health related quality of life compared with standard treatment alone. The findings are expected to provide evidence for a safe, affordable, and locally available nutritional intervention that may complement conventional tuberculosis management.
Inclusion: Male or female aged ≥18 years; Body Mass Index (BMI) <22.9 kg/m²; Newly diagnosed pulmonary tuberculosis (TB); Diagnosis confirmed by bacteriological and/or clinical-radiological findings; Have not received anti-tuberculosis treatment, or have received treatment for less than two weeks; Willing to participate in the study by providing written informed consent and signing the Informed Consent Form.
Exclusion: Patients with drug-resistant tuberculosis, including MDR-TB or XDR-TB, or patients who previously failed an anti-tuberculosis treatment regimen; Patients who have consumed snakehead fish supplements, curcuma supplements, or high-dose multivitamin supplements within the previous two weeks; Individuals with comorbidities such as diabetes mellitus, HIV, impaired kidney function, or impaired liver function; Patients with extrapulmonary tuberculosis; Patients with a history of allergy to fish or turmeric-derived products. Patients with swallowing disorders or gastrointestinal diseases that may affect supplement absorption; Pregnant or breastfeeding women; Individuals who are overweight or obese; Patients who are uncooperative or discontinue treatment before completing the study.