Effects of Adding Vagal Neuromodulation to Manual Therapy in Women With Fibromyalgia
Key facts
- Where
- Mersin, TürkiyeSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07894588, who can take part
Where in Türkiye
- Physiotherapist Taha Emre Baz Private health professional service unitMersin, TürkiyeContact: Taha Emre Baz, BScNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Hasan Kalyoncu University
- Trial code
- NCT07894588
- Record updated
- 26 October 2026
- Original description
The aim of this study is to investigate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) added to manual therapy on pain, autonomic nervous system function, and illness perception in female patients diagnosed with fibromyalgia, using a randomized sham-controlled design.Read full original descriptionShow less
Effect of Vagal Neuromodulation Added to Manual Therapy on Pain, Autonomic Nervous System, and Illness Perception in Women With Fibromyalgia
The aim of this study is to investigate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) added to manual therapy on pain, autonomic nervous system function, and illness perception in female patients diagnosed with fibromyalgia, using a randomized sham-controlled design.
Inclusion: Diagnosis of fibromyalgia according to the 2016 American College of Rheumatology (ACR) criteria, made by a physician; Female, aged 18-65 years; Symptomatic for at least 3 months; Pain intensity of 4 or higher on the Numeric Rating Scale (NRS ≥ 4; moderate to severe pain); Able to read and write and understand Turkish; Willing to participate in the study (voluntary informed consent).
Exclusion: Manual therapy or electrotherapy treatment within the last 3 months; Inflammatory rheumatologic disease (e.g., rheumatoid arthritis, systemic lupus erythematosus); Active cardiac arrhythmia or implanted pacemaker; History of vagus nerve damage or vagotomy; Uncontrolled psychiatric disorder; Pregnancy or breastfeeding.