Long-term epilepsy in children who had a stroke around birth
Reviews past records of epilepsy after a stroke in newborns.
Plain-language title generated from the registry record
Registry title: Long-Term Epilepsy Outcomes in Children With a History of Perinatal Stroke
Key facts
- Where
- Strasbourg, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 5 and 25 years old?
Source: NCT07898397, who can take part
Where in France
- Service de Pédiatrie 1 - Hôpital de Hautepierre - CHU de Strasbourg, FranceStrasbourg, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Strasbourg, France
- Trial code
- NCT07898397
- Record updated
- 27 October 2026
- Original description
Perinatal stroke is a rare condition affecting approximately 20-40 births per 100,000. It may be ischemic or hemorrhagic and can occur before or around birth, with diagnosis sometimes delayed until motor or cognitive symptoms emerge. Potential long-term consequences include motor deficits, cognitive and learning difficulties, language disorders, and epilepsy.Read full original descriptionShow less
Long-Term Epilepsy Outcomes in Children With a History of Perinatal Stroke
Perinatal stroke is a rare condition affecting approximately 20-40 births per 100,000. It may be ischemic or hemorrhagic and can occur before or around birth, with diagnosis sometimes delayed until motor or cognitive symptoms emerge. Potential long-term consequences include motor deficits, cognitive and learning difficulties, language disorders, and epilepsy.
Post-stroke epilepsy is estimated to affect approximately 30% of children who experience perinatal stroke. Although neonatal outcomes are relatively well characterized, the long-term course of epilepsy in this population and the relationship between initial stroke characteristics and subsequent epilepsy outcomes remain insufficiently studied.
The primary objective of this retrospective, multicenter, observational study is to characterize the long-term course of epilepsy in children who experienced an ischemic or hemorrhagic stroke before 28 days of age.
Inclusion: Minors aged 5 to under 18 years or adults aged 18 to 25 years; Patients who attended one of the two participating centers: Strasbourg University Hospitals or Necker Hospital (AP-HP); Confirmed or suspected ischemic or hemorrhagic stroke occurring before 28 days of age; During follow-up, presentation of criteria for focal epilepsy, infantile spasms, continuous spike-and-wave during sleep (CSWS), or Lennox-Gastaut syndrome.
Exclusion: Birth before 34 weeks of gestation; Birth weight below 1,500 g; Perinatal hypoxic-ischemic injury with residual MRI lesions; Insufficient information in medical records; Refusal to participate in the study.