Eloralintide Study for Weight, Diabetes and Heart Risk in Adults
Tests eloralintide against placebo in adults with obesity, diabetes and heart risk.
Plain-language title generated from the registry record
Registry title: A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular Risk
Key facts
- Where
- Beijing, Chengdu, Guangzhou, Hangzhou, Harbin, Jinan, Liaoyou, Luoyang Shi, Nanjing, Shanghai, Shijiazhuang, Tianjin, Wenzhou, Xuzhou, Yibin, and Zigong, ChinaSee the 21 sites
- Phase
- Phase 3
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 45 and 64 years old?
Source: NCT07900633, who can take part
Where in China
- Peking University Third HospitalBeijing, ChinaNo longer taking part
- Xuanwu Hospital, Capital Medical UniversityBeijing, ChinaNo longer taking part
- Sichuan Provincial People's HospitalChengdu, ChinaNo longer taking part
- West China Hospital，Sichuan UniversityChengdu, ChinaNo longer taking part
- Zhujiang HospitalGuangzhou, ChinaNo longer taking part
- The Second Affiliated Hospital of Zhejiang University School of Medicine - Jiefanglu CampusHangzhou, ChinaNo longer taking part
- The First Hospital of Harbin Medical UniversityHarbin, ChinaNo longer taking part
- Jinan Central HospitalJinan, ChinaNo longer taking part
- Panjin Liaoyou Baoshihua HospitalLiaoyou, ChinaNo longer taking part
- The First Affiliated Hospital of Henan University of Science &TechnologyLuoyang Shi, ChinaNo longer taking part
- Nanjing First HospitalNanjing, ChinaNo longer taking part
- Zhongda Hospital Southeast UniversityNanjing, ChinaNo longer taking part
- Jiading District Central HospitalShanghai, ChinaNo longer taking part
- Shanghai Putuo District Center HospitalShanghai, ChinaNo longer taking part
- Hebei General HospitalShijiazhuang, ChinaNo longer taking part
- The Third Hospital of Hebei Medical UniversityShijiazhuang, ChinaNo longer taking part
- Tianjin Medical University General HospitalTianjin, ChinaNo longer taking part
- The 2nd Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical UniversityWenzhou, ChinaNo longer taking part
- The Affiliated Hospital of Xuzhou Medical CollegeXuzhou, ChinaNo longer taking part
- The Second People's Hospital of YibinYibin, ChinaNo longer taking part
- Zigong First People's HospitalZigong, ChinaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Eli Lilly and Company
- Trial code
- NCT07900633EU 2026-525919-14-00
- Record updated
- 3 November 2026
- Original description
The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with a placebo in participants with obesity or overweight, type 2 diabetes, and increased cardiovascular risk.Read full original descriptionShow less
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Once-Weekly Eloralintide in Adult Participants With Obesity or Overweight, Type 2 Diabetes, and Increased CV Risk
The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with a placebo in participants with obesity or overweight, type 2 diabetes, and increased cardiovascular risk.
Inclusion: Have type 2 diabetes; Have a HbA1c value between ≥ 6.5% and ≤ 9.5% at screening; Are on stable treatment with an unchanged dose of at least 1 and no more than 4 antihyperglycemic therapies for at least 90 days before screening; Have an increased risk of cardiovascular events; Have a BMI ≥ 25.0 kg/m2 at screening; Have a stable body weight (<5% body weight change) for 90 days prior to screening; Have a history of at least one self-reported unsuccessful dietary effort to reduce body weight.
Exclusion: Have a prior or planned surgical treatment for obesity (liposuction, cryolipolysis, or abdominoplasty allowed if performed >1 year before screening); Have a prior or planned endoscopic procedure and/or device-based therapy for obesity (prior device-based therapy acceptable if device removal was more than 6 months prior to screening); Have had within 60 days prior to screening:; acute myocardial infarction; stroke; hospitalization for congestive heart failure, or; coronary, peripheral, or carotid artery revascularization procedure; Have received treatment combining sulfonylurea and insulin within 90 days prior to screening; Have type 1 diabetes; Have a history or diagnosis of New York Heart Association Functional Classification IV congestive heart failure.