High-flow nasal oxygen during endoscopy at high altitude in adults at sleep apnea risk
Compares high-flow nasal oxygen with standard oxygen for low blood oxygen during endoscopy.
Plain-language title generated from the registry record
Registry title: Effect of High-flow Nasal Cannula Oxygenation on the Incidence of Hypoxemia During Painless Gastrointestinal Endoscopy in Patients at High Risk for Obstructive Sleep Apnea Syndrome in High-altitude Regions
Key facts
- Where
- Hangzhou, Sanjiaocheng, and Xining, ChinaSee the 3 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who live at high altitude, are at high risk for obstructive sleep apnea, and are scheduled for sedated stomach or bowel endoscopy.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- STOP-Bang score of 5 or more (high risk for obstructive sleep apnea). Scheduled for sedated gastroscopy, colonoscopy, or both.
- Earlier treatment
- No planned breathing tube (endotracheal intubation) and no earlier tracheostomy.
- Biomarker or test result
- Lives long-term in a high-altitude region (continuous residence there within the past 1 year).
Main reasons for not taking part
- Conditions that rule out high-flow nasal oxygen, such as complete upper airway obstruction, skull base or nasal bone fracture, pneumothorax, or pneumomediastinum
- ASA physical status above IV
- Confirmed pregnancy or current breastfeeding
- Allergy to sedatives such as propofol
- Taking part in another clinical trial
Read by machine on 12 November 2026.
Where in China
- The First Affiliated Hospital Zhejiang University School of MedicineHangzhou, ChinaContact: Diansan SuNo longer taking part
- Haiyan County People's HospitalSanjiaocheng, ChinaContact: Peng QiaoNo longer taking part
- Qinghai Provincial Traffic HospitalXining, ChinaContact: Yunyun LiNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Diansan Su
- Trial code
- NCT07904260
- Record updated
- 29 October 2026
- Original description
Patients living in high-altitude areas naturally have lower blood oxygen levels. Those at high risk for Obstructive Sleep Apnea (OSA) face an even greater risk of low oxygen during painless gastrointestinal endoscopy. This multicenter study will randomly assign these patients to receive either High-Flow Nasal Oxygen (HFNC) or standard oxygen therapy during their procedure, aiming to find out if HFNC can safely and effectively reduce the risk of low oxygen events.Read full original descriptionShow less
Effect of High-flow Nasal Cannula Oxygenation on the Incidence of Hypoxemia During Painless Gastrointestinal Endoscopy in Patients at High Risk for Obstructive Sleep Apnea Syndrome in High-altitude Regions: a Multicenter Randomized Controlled Trial
Patients living in high-altitude areas naturally have lower blood oxygen levels. Those at high risk for Obstructive Sleep Apnea (OSA) face an even greater risk of low oxygen during painless gastrointestinal endoscopy. This multicenter study will randomly assign these patients to receive either High-Flow Nasal Oxygen (HFNC) or standard oxygen therapy during their procedure, aiming to find out if HFNC can safely and effectively reduce the risk of low oxygen events.
Inclusion: Age ≥18 years; Long-term residence in a high-altitude region (continuous residence in a high-altitude region within the past 1 year); STOP-Bang score ≥5; Scheduled for sedated gastrointestinal endoscopy (gastroscopy, colonoscopy, or combined gastroscopy + colonoscopy); Patients have signed the informed consent form.
Exclusion: Patients with absolute contraindications to high-flow nasal oxygen therapy, including confirmed complete upper airway obstruction, skull base fracture, nasal bone fracture, pneumothorax, or pneumomediastinum; Prior tracheostomy; Allergy to sedatives such as propofol; ASA physical status > IV; Planned endotracheal intubation; Confirmed pregnancy or current breastfeeding; Current participation in another clinical trial; Patients deemed unsuitable for this trial by the investigator.