tSCS Combined With Rehabilitation Training in Treating Paraplegic Patients After SCI
Key facts
- Where
- Beijing, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT07907952, who can take part
Where in China
- Beijing Tsinghua Chang Gung HospitalBeijing, ChinaContact: Yang Lu, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Beijing Tsinghua Chang Gung Hospital
- Trial code
- NCT07907952
- Record updated
- 30 October 2026
- Original description
This clinical trial aims to evaluate the safety and efficacy of transcutaneous spinal cord stimulation (tSCS) combined with rehabilitation training for treating paraplegia after spinal cord injury (SCI). Previous studies have shown that applying tSCS in the thoracolumbar region can enable patients with complete and incomplete SCI to immediately restore partial voluntary movement, but there are currently no domestic reports on the treatment of SCI paraplegia using tSCS combined with rehabilitation training. The main questions this study aims to answer include: 1. Compared with using tSCS alone, does combined rehabilitation therapy enable patients to better restore voluntary movement? 2. Will this treatment protocol result in fewer adverse events? 3. Can the tSCS combined with rehabilitation training protocol be applied to a large number of patients with paraplegia after SCI to help them restore voluntary movement?For paraplegic patients with SCI (spinal cord injury) whose injury duration exceeds 1 week, baseline data (pre-stimulation, at the end of the first week of stimulation, and post-experiment) need to be collected after assessment. After adjusting the stimulation parameters of tSCS (transcutaneous spinal cord stimulation) and modifying the rehabilitation training plan, a one-month personalized rehabilitation training program will be conducted, followed by at least four weeks of follow-up. Researchers will compare the assessment results recorded at different stages and use specific indicators to evaluate the safety and effectiveness of this treatment protocol.Read full original descriptionShow less
Clinical Trial on the Safety and Efficacy of Transcutaneous Spinal Cord Stimulation Combined With Rehabilitation Training in the Treatment of Paraplegic Patients After Spinal Cord Injury
This clinical trial aims to evaluate the safety and efficacy of transcutaneous spinal cord stimulation (tSCS) combined with rehabilitation training for treating paraplegia after spinal cord injury (SCI). Previous studies have shown that applying tSCS in the thoracolumbar region can enable patients with complete and incomplete SCI to immediately restore partial voluntary movement, but there are currently no domestic reports on the treatment of SCI paraplegia using tSCS combined with rehabilitation training. The main questions this study aims to answer include: 1. Compared with using tSCS alone, does combined rehabilitation therapy enable patients to better restore voluntary movement? 2. Will this treatment protocol result in fewer adverse events? 3. Can the tSCS combined with rehabilitation training protocol be applied to a large number of patients with paraplegia after SCI to help them restore voluntary movement?For paraplegic patients with SCI (spinal cord injury) whose injury duration exceeds 1 week, baseline data (pre-stimulation, at the end of the first week of stimulation, and post-experiment) need to be collected after assessment. After adjusting the stimulation parameters of tSCS (transcutaneous spinal cord stimulation) and modifying the rehabilitation training plan, a one-month personalized rehabilitation training program will be conducted, followed by at least four weeks of follow-up. Researchers will compare the assessment results recorded at different stages and use specific indicators to evaluate the safety and effectiveness of this treatment protocol.
Inclusion: Age between 18 and 60 years old; Spinal cord injury classified as AIS Grade A, B, C, or D, with the distance between the injury level and the conus medullaris at least 60mm; Able to cooperate with rehabilitation training; Stable and healthy physiological condition, as determined by the researcher; must be able to complete the entire study period and cooperate with rehabilitation training.
Exclusion: 1. Obvious mental disorders (anxiety, depression, etc.) resulting in inability to complete relevant subjective assessments2. Presence of mental or cognitive impairments preventing participation in transcutaneous spinal electrical stimulation and follow-up3. Severe autonomic reflex disorders4. Severe muscle atrophy or joint contractures5. Life expectancy less than 1 year6. Progressive spinal instability or severe spinal deformities7. Uncontrolled hypertension, severe heart disease, or serious medical/respiratory conditions8. Severe hydronephrosis or renal dysfunction9. Individuals considered unsuitable by the researcher.