Studying brain signals to predict response to vagus nerve stimulation in epilepsy
Studies brain connectivity before and after vagus nerve stimulation in adults with refractory epilepsy.
Plain-language title generated from the registry record
Registry title: Identification of Biomarkers for Vagus Nerve Stimulation in Patients With Refractory Epilepsy
Key facts
- Where
- Brussels, BelgiumSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with epilepsy that does not respond to medicines, who are planned to get a vagus nerve stimulation (VNS) implant.
- Age
- Over 18 years; the record lists 18 Years to 79 Years.
- Sex
- All sexes can join.
- Disease stage
- Refractory epilepsy (epilepsy that is hard to control) with a planned VNS implantation.
- Biomarker or test result
- Intellectual Quotient above 55 on the Wechsler scale (normal or mild cognitive impairment).
Main reasons for not taking part
- Laryngeal (voice box) problems, such as recurrent nerve lesions or vocal fold paralysis
- Dementia
- Neurodegenerative diseases
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 79 years old?
Source: NCT07909486, who can take part
Where in Belgium
- Clinique Universitaires Saint-LucBrussels, BelgiumContact: Riëm EL TAHRY, Pr.Taking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
- Trial code
- NCT07909486
- Record updated
- 5 November 2026
- Original description
A VNS longitudinal study focused on pre and post-VNS implantation in order to predict the VNS response and to understand better mechanisms of VNS using some connectivity and network measures.Read full original descriptionShow less
Identification of Biomarkers for Vagus Nerve Stimulation in Patients With Refractory Epilepsy
A VNS longitudinal study focused on pre and post-VNS implantation in order to predict the VNS response and to understand better mechanisms of VNS using some connectivity and network measures.
Inclusion: Patients aged >18 years; Intelectual Quotient >55 on Wechsler scale (normal or mild cognitive impairment); Patients have refractory epilepsy and are planned for VNS implantation.
Exclusion: Concomitant laryngeal pathology (e.g. recurrent nerve lesions, vocal fold paralysis); Dementia/ Neurodegenerative diseases.