Intensive rehabilitation with technology for long-term stroke or spinal cord injury
Follows adults after intensive rehabilitation and tests a second round of training.
Plain-language title generated from the registry record
Registry title: Long-Term Clinical, Health Economic, and Process Evaluation of Intensive Technology-Integrated Motor Rehabilitation in Chronic Neurological Conditions (INTeRAcT-bis)
Key facts
- Where
- Herentals and Leuven, BelgiumSee the 2 sites
Where in Belgium
- AZ HerentalsHerentals, BelgiumNo longer taking part
- KU LeuvenLeuven, BelgiumNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- KU Leuven
- Trial code
- NCT07912320
- Record updated
- 3 November 2026
- Original description
Rehabilitation remains important in the chronic phase after stroke or spinal cord injury, as meaningful improvements may still be achieved through intensive, goal-directed, and personalized training. INTeRAcT-bis is a follow-up study of the original INTeRAcT program, which consisted of a 3-week intensive rehabilitation intervention (90 therapy hours) combining conventional therapy, goal-directed training, self-management, and advanced rehabilitation technologies. The study has two main objectives: (1) to evaluate the long-term clinical and health economic effects of the original INTeRAcT program, and (2) to assess the clinical effects and implementation of a second intensive rehabilitation period ("boost"). Participants receive a personalized 3-week rehabilitation program targeting upper and/or lower limb impairments based on their individual goals. In addition to clinical and health economic outcomes, the study examines participant experiences and implementation factors to support a broader implementation of intensive rehabilitation in the future.Read full original descriptionShow less
Long-Term Clinical, Health Economic, and Process Evaluation of Intensive Technology-Integrated Motor Rehabilitation in Chronic Neurological Conditions (INTeRAcT-bis)
Rehabilitation remains important in the chronic phase after stroke or spinal cord injury, as meaningful improvements may still be achieved through intensive, goal-directed, and personalized training. INTeRAcT-bis is a follow-up study of the original INTeRAcT program, which consisted of a 3-week intensive rehabilitation intervention (90 therapy hours) combining conventional therapy, goal-directed training, self-management, and advanced rehabilitation technologies. The study has two main objectives: (1) to evaluate the long-term clinical and health economic effects of the original INTeRAcT program, and (2) to assess the clinical effects and implementation of a second intensive rehabilitation period ("boost"). Participants receive a personalized 3-week rehabilitation program targeting upper and/or lower limb impairments based on their individual goals. In addition to clinical and health economic outcomes, the study examines participant experiences and implementation factors to support a broader implementation of intensive rehabilitation in the future.
Inclusion: Voluntary written informed consent of the participant or their legally authorized representative has been obtained prior to any screening procedures; A diagnosis of central neurological disease, made by a specialist. Conditions may include stroke or spinal cord injury:; Stroke:; Participants must have received a diagnosis of stroke and have been diagnosed at least 3 months ago; Participants who are diagnosed for the second time, but returned to normal functioning after the first stroke diagnosis (Barthel Index > 85/100), and the affected side is the same as the first stroke; SCI: Participants have a rating A, B, C or D on the American Spinal Injury Association (ASIA) measurement scale, which refers to patients with complete or incomplete impairment. All levels of SCI can be included, if there is a clear patient need linked to the upper and/or lower extremities; At least 3 months post-discharge from hospital/rehabilitation center, living at home; Had a normal functional state prior to the pathology: a pre-pathology Barthel Index > 85/100; Unilateral or bilateral weakness of the affected upper or lower limbs (No maximum score in all affected limbs = motricity index: score 5 on 3/3 segments); Having the clinical opportunity to engage in exercise therapy with available technology, assessed by a specialist (under supervision of an MD); Age of > 18 years; Sufficient cognitive ability to understand the therapy exercises and give informed consent, assessed by a specialist (under supervision of an MD); Having participated in the first INTeRAcT study.
Exclusion: Having other neurological or musculoskeletal conditions that may affect the protocol, assessed by a specialist (under supervision of an MD); Severe visual impairment, communication, cognitive, and language formation problems that would prevent the intervention and measurement process, assessed by a specialist (under supervision of an MD); Any disorder, which in the investigator's opinion might compromise the participant's safety or compliance with the CIP; No ability to initiate movements against gravity in the upper and lower limbs; A female who is pregnant or breastfeeding.