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Adapting a Behavioral Activation Program for Older Adults With HIV and Depression

Adapts and pilots a depression program for older adults living with HIV.

Plain-language title generated from the registry record
Registry title: Adapting the "Do More, Feel Better" Intervention for Older People Living With HIV

Key facts

Where
Seattle, United StatesSee the site

Where in United States

  • University of WashingtonSeattle, United StatesNo longer taking part

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Trial details

Who runs it
University of Washington
Trial code
NCT07915934
Record updated
4 November 2026
Original description
More than half of people living with HIV (PWH) in the United States are 50 years of age or older. Older PWH have a 2.3-fold increased risk of depression compared to their peers without HIV. The investigator team has developed a streamlined lay-delivered behavioral activation intervention called "Do More, Feel Better" that has been shown to decrease depressive symptoms among older adults obtaining services in community senior centers. The investigators propose to (1) identify barriers and facilitators to improving mental health among older PWH by using this intervention in the context of Ryan White case management services, (2) adapt and enhance the intervention to meet the needs of older PWH, and (3) conduct a pilot randomized controlled trial to determine the acceptability, feasibility, and appropriateness of the adapted DMFB intervention.Read full original descriptionShow less

Adapting the "Do More, Feel Better" Intervention for Older People Living With HIV

More than half of people living with HIV (PWH) in the United States are 50 years of age or older. Older PWH have a 2.3-fold increased risk of depression compared to their peers without HIV. The investigator team has developed a streamlined lay-delivered behavioral activation intervention called "Do More, Feel Better" that has been shown to decrease depressive symptoms among older adults obtaining services in community senior centers. The investigators propose to (1) identify barriers and facilitators to improving mental health among older PWH by using this intervention in the context of Ryan White case management services, (2) adapt and enhance the intervention to meet the needs of older PWH, and (3) conduct a pilot randomized controlled trial to determine the acceptability, feasibility, and appropriateness of the adapted DMFB intervention.

Inclusion: ≥50 years of age; living with HIV; English-speaking; elevated depressive symptoms (PHQ-9 ≥10); resident in Washington for ≥1 year; assigned to a Ryan White case manager; willing to undergo all study procedures.

Exclusion: a diagnosis of bipolar disorder, schizophrenia or psychosis; dementia or Telephone Interview for Cognitive Status-modified (TICS-M) scores <21; active suicidal ideation; current regular psychotherapy; antidepressant use, unless at stable doses for 12 weeks.

ClinicalTrials.gov NCT07915934