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NCT07922642Not yet recruiting

Nurse-Led Prehabilitation Before Major Abdominal Cancer Surgery

Run by Alexandria University

Effect of a Nurse-Led Multimodal Prehabilitation Program on Postoperative Complications in Patients Undergoing Major Elective Abdominal Cancer Surgery: A Mixed-Methods Randomized Controlled Trial

Source: ClinicalTrials.gov · Last updated 6 Nov 2026

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Brief summary (registry, in English)

Many people who have major planned surgery for abdominal cancer develop complications afterwards, which can prolong hospital stay and slow recovery. This study tests whether a four-week program led by a trained oncology nurse, started before surgery, reduces these complications. The program combines supervised and home exercise (walking, resistance and breathing exercises), nutrition counseling with protein targets and supplements when needed, education and relaxation techniques to reduce anxiety, and advice on stopping smoking and alcohol. Adults at one hospital will be randomly assigned, in equal numbers, to the program plus usual care or to usual care alone; 104 participants are planned. The main outcome is the Comprehensive Complication Index, a score from 0 to 100 that combines all complications within 30 days after surgery, graded by an assessor who does not know the group. Other outcomes include serious complications, distance walked in six minutes, quality of life, length of hospital stay, hospital readmission, time to first getting out of bed, and adherence to the program. In a qualitative part, 12 to 15 participants from the program group will be interviewed about their experiences, barriers and acceptability. Results from both parts will be combined to interpret the findings.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
104 (estimated)
First submitted
2 Nov 2026
Start date
10 Nov 2026
Primary completion date
5 Feb 2027
Lead sponsor
Alexandria University
NCT number
NCT07922642

What you commit to

  • Study type: Interventional
  • Planned participants: 104
  • From 10 Nov 2026 to the primary completion date, 5 Feb 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study design.

AI-kivonat: who the study is looking for

Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with abdominal cancer who are scheduled for planned major abdominal surgery. It tests a nurse-led four-week program before surgery.

Age
18 years or older
Sex
All sexes
Disease stage
Confirmed or suspected abdominal cancer (colorectal, gastric, pancreatic, hepatobiliary or other major abdominal resection). Planned open or laparoscopic surgery at least 3 weeks after enrollment. ECOG performance status 0 to 2.
Earlier treatment
Cannot already be in a structured exercise program.

Main reasons for not taking part

  • Emergency or urgent surgery
  • Unstable heart or lung disease, or a medical reason not to exercise
  • Severe bone, muscle or nerve condition that prevents walking
  • Cognitive impairment that prevents following the program or filling in questionnaires
  • Already in a structured exercise program

Read by machine on 9 Nov 2026.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Emergency or urgent surgery

Other illness

  • Unstable cardiac or respiratory disease, or any medical contraindication to exercise as judged by the treating physician
  • Severe musculoskeletal or neurological condition preventing walking
  • Cognitive impairment that prevents following the program or completing questionnaires

Other

  • Already participating in a structured exercise program

Who the study is looking for

  • Adults aged 18 years or older
  • Histologically confirmed or suspected abdominal cancer (colorectal, gastric, pancreatic or hepatobiliary, or other major abdominal resection)
  • Scheduled for elective major open or laparoscopic abdominal surgery, with at least 3 weeks between enrollment and the planned surgery date
  • ECOG performance status 0 to 2
  • Able to give written informed consent and communicate in Arabic

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Faculty of Nursing, Alexandria UniversityAlexandriaEgyptUnknown status

Are you the coordinator? Confirm the details

The registry text, word for word

This page is information, not medical advice. Discuss any trial with your doctor.