Checking Small Airway Problems in Rheumatoid Arthritis and Systemic Sclerosis
Tests breathing and lung scans in adults with rheumatoid arthritis or systemic sclerosis.
Plain-language title generated from the registry record
Registry title: Small Airway Dysfunction in Rheumatoid Arthritis and Systemic Sclerosis
Key facts
- Where
- Paris, FranceSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with rheumatoid arthritis or systemic sclerosis, to study problems in the small airways of the lungs.
- Age
- 18 years or older
- Sex
- All sexes
- Disease stage
- Rheumatoid arthritis or systemic sclerosis, confirmed by a rheumatologist
- Earlier treatment
- People who had treatment with medicines known to cause lung scarring (bleomycin, amiodarone) or earlier radiation therapy for chest cancers cannot join.
Main reasons for not taking part
- Interstitial lung disease found before joining
- Past treatment with bleomycin or amiodarone, or radiation therapy for breast or lung cancer
- Unable to do the lung function tests (impulse oscillometry, forced spirometry, plethysmography)
- Pregnant or breastfeeding women, minors, adults under legal guardianship, people deprived of liberty
- Does not understand the French language
Read by machine on 10 November 2026.
Where in France
- Rheumatology Department, Cochin HospitalParis, FranceNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Assistance Publique - Hôpitaux de Paris
- Trial code
- NCT07924124
- Record updated
- 9 November 2026
- Original description
The purpose of this prospective real-world study is to assess the presence and severity of small airway dysfunction in patients with rheumatoid arthritis or systemic sclerosis and to examine the relationships between the various markers of small airway dysfunction and disease activity.Read full original descriptionShow less
Study on Small Airway Dysfunction in Rheumatoid Arthritis and Systemic Sclerosis
The purpose of this prospective real-world study is to assess the presence and severity of small airway dysfunction in patients with rheumatoid arthritis or systemic sclerosis and to examine the relationships between the various markers of small airway dysfunction and disease activity.
Inclusion: Patients ≥ 18 years of age; Diagnosis of rheumatoid arthritis (RA) or systemic sclerosis (SSc) confirmed by a rheumatologist; Patients affiliated with or covered by a social security scheme; Patients who have received information regarding the research and have signed the consent form.
Exclusion: Presence of interstitial lung disease (ILD) identified prior to recruitment; History of treatment with medications known to induce pulmonary fibrosis (bleomycin, amiodarone) or prior radiation therapy for the local treatment of thoracic malignancies (breast cancer, lung cancer); Patients unable to perform any of the following pulmonary function tests (PFTs):; Impulse oscillometry (IOS); Forced spirometry; Measurement of lung volumes via plethysmography; Individuals covered under Articles L1121-5 to 1121-8 of the French Public Health Code (minors, adults under legal guardianship or curatorship, individuals deprived of their liberty, pregnant or breastfeeding women); Patients who do not understand the French language.