Acute Pain Management of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell Disease in the Emergency Department: a Comparative Study.
Key facts
- Where
- Reims, Strasbourg, and Vandœuvre-lès-Nancy, FranceSee the 3 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 0 and 17 years old?
Source: NCT07925372, who can take part
Where in France
- CHU de Reims American Memorial HospitalReims, FranceNo longer taking part
- Hôpitaux Universitaires de Strasbourg - Hôpital de HautepierreStrasbourg, FranceNo longer taking part
- CHRU de Nancy - Hôpital d'enfants - Urgences pédiatriquesVandœuvre-lès-Nancy, FranceNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Central Hospital, Nancy, France
- Trial code
- NCT07925372
- Record updated
- 9 November 2026
- Original description
This retrospective observational multicenter study aims to describe the management of acute pain in children with sickle cell disease treated in the emergency departments of the University Hospitals of Nancy, Strasbourg, and Reims, France. The study analyzed routinely collected medical data from pediatric patients presenting with acute painful episodes related to sickle cell disease. Information regarding pain assessment, analgesic treatment, timing of care, and clinical outcomes was reviewed. No additional procedures or interventions were performed for the purpose of this study. All data were collected as part of standard clinical care. The results of this study may help improve the management of acute pain in children with sickle cell disease in emergency settings.Read full original descriptionShow less
This retrospective observational multicenter study aims to describe the management of acute pain in children with sickle cell disease treated in the emergency departments of the University Hospitals of Nancy, Strasbourg, and Reims, France. The study analyzed routinely collected medical data from pediatric patients presenting with acute painful episodes related to sickle cell disease. Information regarding pain assessment, analgesic treatment, timing of care, and clinical outcomes was reviewed. No additional procedures or interventions were performed for the purpose of this study. All data were collected as part of standard clinical care. The results of this study may help improve the management of acute pain in children with sickle cell disease in emergency settings.
Inclusion: Age 0 to 17 years; Confirmed diagnosis of sickle cell disease (SS, SC, Sβ0, Sβ+); Emergency department visit for painful vaso-occlusive crisis; Medical record available with complete documentation of pain management.
Exclusion: Emergency department visit for a reason other than vaso-occlusive crisis; Pain not related to vaso-occlusive crisis; Incomplete medical record.