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To Evaluate The Efficacy And Safety Of Rivaroxaban In Combination With Aspirin Compared With Aspirin Monotherapy In Patients With Stable Coronary Artery Disease (CAD) and High Ischemic Risk

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Trial details

Who runs it
Republican Specialized Scientific and Practical Medical Center of Cardiology
Trial code
NCT07928583
Record updated
10 November 2026
Original description
This study compares rivaroxaban plus aspirin with aspirin alone in patients with stable coronary artery disease at high ischemic risk. The aim is to evaluate whether the combination therapy better prevents cardiovascular events and to assess its safety.Read full original descriptionShow less

This study compares rivaroxaban plus aspirin with aspirin alone in patients with stable coronary artery disease at high ischemic risk. The aim is to evaluate whether the combination therapy better prevents cardiovascular events and to assess its safety.

Inclusion: Age 18 years or older; Stable coronary artery disease; High ischemic risk; Able to provide informed consent.

Exclusion: Active bleeding or high bleeding risk; Severe renal or hepatic impairment; Contraindication to rivaroxaban or aspirin; Pregnancy or breastfeeding.

ClinicalTrials.gov NCT07928583