Identification of Cognitive and Motor Changes in Individuals With and Without Parkinson's Disease Using Hemoencephalography
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Trial details
- Who runs it
- Federal University of Uberlandia
- Trial code
- NCT07931677
- Record updated
- 12 November 2026
- Original description
This is an observational, longitudinal study with a control group, with the general objective of analysing the pattern of response of prefrontal cortex activity during motor and cognitive tasks in individuals with and without Parkinson's disease (PD) over 12 months. Prefrontal activity was recorded with a portable hemoencephalography (HEG) device placed on the forehead, in rest-task-rest blocks, while participants performed the Box and Block Test, the Nine-Hole Peg Test, the Trail Making Test (parts A and B) and spiral and sinusoid drawings. The assessments were repeated in up to 12 sessions, planned approximately monthly, and the tasks were video-recorded showing only the hands. Participants with PD were also assessed with the MDS-UPDRS Part III, the Hoehn \& Yahr scale and the PDQ-39 at the first and last sessions. Information that can identify the participants will be removed from the database before storage in a repository. The results will contribute to understanding how prefrontal activity relates to motor and cognitive performance in PD and how it changes over time.Read full original descriptionShow less
This is an observational, longitudinal study with a control group, with the general objective of analysing the pattern of response of prefrontal cortex activity during motor and cognitive tasks in individuals with and without Parkinson's disease (PD) over 12 months. Prefrontal activity was recorded with a portable hemoencephalography (HEG) device placed on the forehead, in rest-task-rest blocks, while participants performed the Box and Block Test, the Nine-Hole Peg Test, the Trail Making Test (parts A and B) and spiral and sinusoid drawings. The assessments were repeated in up to 12 sessions, planned approximately monthly, and the tasks were video-recorded showing only the hands. Participants with PD were also assessed with the MDS-UPDRS Part III, the Hoehn \& Yahr scale and the PDQ-39 at the first and last sessions. Information that can identify the participants will be removed from the database before storage in a repository. The results will contribute to understanding how prefrontal activity relates to motor and cognitive performance in PD and how it changes over time.
Inclusion: Experimental group: diagnosis of Parkinson's disease; Experimental group: classified between stages 0 and 3 of the Hoehn \& Yahr scale; Experimental group: on antiparkinsonian medication; Both groups: no previous cardiorespiratory or musculoskeletal disorder.
Exclusion: Visual impairment that affects the tests (Snellen < 80); Use of deep brain stimulation; Mini-Mental State Examination below the education-adjusted cut-off (20 for 1-4 years of schooling, 25 for 5-8 years, 26.5 for 9-11 years and 29 for more than 11 years).