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PreCharge: An Innovative Digital Program to Increase Coping, Resilience, and Health Care Engagement Among Cancer Previvors

Key facts

Who runs it
Pro-Change Behavior Systems
Trial code
Status
Not yet recruiting
People taking part
574 people, planned
Started
Nov 2026
Expected to end
Sept 2027
Type of study
Interventional, 2 groupsOne group gets no study treatment, for comparison.
Treatments tested
  • PreCharge digital psychosocial support program
Record updated
13 November 2026

Who can take part

Age
18 years and older
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

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Who can take part

  • Age 18 years or older
  • Reside in the United States
  • Self-report having a hereditary cancer syndrome
  • Able to read and communicate in English
  • Willing to receive text messages during the 6-month study period
  • Score of 100 or less on the 12-item Cancer Behavior Inventory-Brief Version (CBI-B) at screening

Who cannot take part

  • Self-reported personal history of cancer, except non-melanoma skin cancer

About the trial

What the trial wants to find out

The goal of this clinical trial is to learn if PreCharge helps adults cope with an inherited risk of cancer. PreCharge is a personalized online support program for people with a hereditary cancer syndrome. The study is for adults who have not had cancer, with an exception for non-melanoma skin cancer.

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The main question the study aims to answer is:

• Does PreCharge help participants feel more confident in their ability to cope with their inherited cancer risk? Researchers will compare participants who use PreCharge with participants who do not use the program during the study. Researchers will also look at participants' resilience, anxiety, depressive symptoms, cancer worry, and overall well-being.

Participants will be assigned by chance to one of two groups. Participants in both groups will answer online surveys at the start of the study and about 3 and 6 months later.

* Participants in the PreCharge group will have access to the program for 6 months. They will receive text messages and can use the online program's information and activities. * Participants in the comparison group will have access to a webpage with mental health and hereditary cancer resources.

The 2 groups in the trial

  • PreChargeTreatment being tested

    Participants receive access to PreCharge, a personalized digital psychosocial support program, for six months. The program includes a web-based portal and text messages that provide tailored information, activities, and support. Participants complete study assessments at baseline and at three and six months.

    Treatment: PreCharge digital psychosocial support program

  • Assessment-Only ControlNo study treatment, for comparison

    Participants complete study assessments at baseline and at three and six months. They do not receive access to the PreCharge program during the study. They have access to a static webpage with mental health and hereditary cancer resources.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Record updated
13 November 2026