HIIT-based Exercise Intervention for Improvement of Immunomodulatory, Cardiopulmonary, and Psychosocial Parameters During Maintenance Therapy of Paediatric Acute Lymphoblastic Leukaemia (HEALL)
Key facts
- Who runs it
- University of Erlangen-Nürnberg Medical School
- Where
- Germany1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Not yet recruiting
- People taking part
- 108 people, planned
- Starts
- 1 Jan 2027
- Expected to end
- 1 Jan 2029
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- HII-Training (HIIT) 6 Months
- Cardiopulmonary exercise testing
- Echocardiography
- Electrocardiography (EKG)
- blood draw
- Questionnaire
- MSOT
- HIT-Training (HIIT) 3 Months
- Record updated
- 13 November 2026
Who can take part
- Age
- 6 years to 10 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 9 criteriaShow less
Who can take part
- Diagnosed acute lymphatic leukemia
- Begin of maintenance therapy
- From 6 to 10 years of age
- Physical ability to participate in HIIT and cardiopulmonary exercise testing
Who cannot take part
- Previous lung surgery
- Critical condition (requiring respiratory support, ventilation, oxygen, shock, symptomatic heart failure)
- Known pleural or pericardial effusion
- Marked thoracic deformities/malformations
- Injuries that do not allow physical stress diagnostics
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 6 and 10 years old?
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
In this study, the investigators aim to examine the effects of high-intensity interval training (HIIT) on cardiopulmonary fitness and immunological recovery in female ALL survivors who underwent cancer treatment during childhood and adolescence.
The 2 groups in the trial
- Intervention GroupExisting treatment, for comparison
Total of 6 months of HIIT
Treatment: HII-Training (HIIT) 6 Months, Cardiopulmonary exercise testing, Echocardiography, Electrocardiography (EKG), blood draw, Questionnaire, and MSOT
- Control GroupExisting treatment, for comparison
3 months without intervention followed by 3 months of HIIT
Treatment: Cardiopulmonary exercise testing, Echocardiography, Electrocardiography (EKG), blood draw, Questionnaire, MSOT, and HIT-Training (HIIT) 3 Months
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Fit questions
- Built from NCT07936786, who can take part
- Record updated
- 13 November 2026