Acute lymphoblastic leukaemia: open trials in Spain

42 open trials have a site in Spain. Registry data; only the trial team decides who can take part.

NCT07223021
A Study of Fludarabine Dosing in Children and Young Adults With B-cell Acute Lymphoblastic Leukemia
Trial Treatment · Phase 3 · Memorial Sloan Kettering Cancer Center
Hospital Sant Joan De Deu Barcelona, Esplugues de Llobregat
Registry updated 2026-11-05
NCT07862946
Inotuzumab as Post-Trasplantation Therapy for Adult High-risk B-cell Precursor Acute Lymphoblastic Leukemia
Trial Treatment · Phase 2 · PETHEMA Foundation
Ico Hospital Germans Trias I Pujol, Badalona · H. de la Santa Creu I Sant Pau, Barcelona · C. H. Gregorio Marañón, Madrid · H. 12 de Octubre, Madrid · C. H. Regional de Málaga , H. General, Málaga · C. Asistencial U. de Salamanca, Salamanca · H Donostia, San Sebastián · H. Marqués de Valdecilla, Santander · Complejo Hosp. Regional Virgen del Rocío, Seville · Hospital Universitari i Politécnic La Fe, Valencia
Registry updated 2026-11-04
NCT06395103
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
Hospital Universitari Vall d'Hebron, Barcelona · Sant Joan De Deu Barcelona Hospital, Esplugues De Llobregat · Hospital Infantil Universitario Nino Jesus, Madrid · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-10-30
NCT07570173
A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)
Trial Treatment · Phase 2/3 · Merck Sharp & Dohme LLC
Institut Catala d'Oncologia, Badalona · Clinica Universidad de Navarra, Madrid · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario Central De Asturias, Oviedo · Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcón · Hospital Universitario De Salamanca, Salamanca · Hospital Clinico Universitario de Valencia, Valencia
Registry updated 2026-10-30
NCT07476729
International Study for Treatment of Childhood Relapsed Precursor B-Cell ALL 2020 (IntReALL BCP 2020)
Trial Treatment · Phase 3 · Charite University, Berlin, Germany
Hospital General Universitario Dr. Balmis, Alicante · Hospital Universitario de Cruces, Barakaldo · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Sant Joan De Deu Barcelona, Esplugues de Llobregat · Hospital Universitario 12 de Octubre, Madrid · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Infantil Universitario Nino Jesus, Madrid · Hospital Universitario La Paz, Madrid · Hospital Universitario Regional de Málaga, Málaga · University Clinical Hospital Virgen De La Arrixaca, Murcia · University Hospital Son Espases, Palma · Complexo Hospitalario Universitario De Santiago, Santiago de Compostela · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital Universitario Y Politecnico La Fe, Valencia · Hospital Universitario Miguel Servet, Zaragoza
Registry updated 2026-10-26
NCT05327894
Interfant-21 Treatment Protocol for Infants Under 1 Year With KMT2A-rearranged ALL or Mixed Phenotype Acute Leukemia
Trial Treatment · Phase 3 · Princess Maxima Center for Pediatric Oncology
Vall D'hebron Institut De Recerca, Barcelona · Hospital Infantil Universitario Nino Jesus, Madrid · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-10-19
NCT07109219
Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia
Trial Treatment · Phase 1/2 · AstraZeneca
Hospital Germans Trias i Pujol, Badalona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Universitario De Salamanca, Salamanca · Hospital Universitario Marqués de Valdecilla, Santander
Registry updated 2026-10-15
NCT07648264
Single-arm Study of IgPro20 in Adults With Secondary Immune Deficiencies Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies
Trial Treatment · Phase 3 · CSL Behring
Hospital Universitari Germans Trias i Pujol, Badalona · Vall d'Hebron Institut d'Oncologia, Barcelona · Hospital Clinic de Barcelona, Barcelona · Hospital Universitario del Vinalopo, Elche · Pratia ES HLA Hospital Universitario Moncloa, Madrid · Hospital Universitario Fundación Jiménez Díaz, Madrid · Hospital Universitario Marqués de Valdecilla, Santander
Registry updated 2026-10-14
NCT06137118
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
Trial Treatment · Phase 1/2 · AstraZeneca
Hospital Universitari Vall d'Hebron, Barcelona · Hospital Clinic de Barcelona, Barcelona · MD Anderson Cancer Center, Madrid · Hospital Universitario La Paz, Madrid · Hospital Universitario De Salamanca, Salamanca · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-10-13
NCT03934372
Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors
Trial Treatment · Phase 1/2 · Incyte Biosciences International Sàrl
Hospital General Universitario Vall D Hebron, Barcelona · Hospital Sant Joan de Deu de Manresa, Barcelona · Hospital Infantil Unversitario Nino Jesus, Madrid · Hospital Universitari i Politécnic La Fe, Valencia
Registry updated 2026-10-09
NCT04065399
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
Trial Treatment · Phase 1/2 · Syndax Pharmaceuticals
Institut Catala D'oncologia, L'Hospitalet de Llobregat · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-10-09
NCT06173518
A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL)
Trial Treatment · Phase 1 · Autolus Limited
Hospital Universitari Vall d'Hebron, Barcelona · Hospital Nino Jesus, Madrid
Registry updated 2026-10-09
NCT07597590
Digital Patient-Reported Assessment in Older Adults With Acute Leukemia
Trial Treatment · Fundación para la Investigación Biosanitaria del Principado de Asturias
Hospital Universitario Central de Asturias (HUCA), Oviedo
Registry updated 2026-10-07
2025-522019-40-00
Study of the safety and efficacy of asciminib in pediatric and young adult participants with r/r Ph+ or ABL-class Ph-like ALL
Trial Treatment · Phase 1/2 · Novartis Pharma AG
Hospital Universitari Vall d'Hebron, Barcelona · Hospital Sant Joan De Deu Barcelona, Esplugues de Llobregat · Hospital Universitario La Paz, Madrid · Hospital Infantil Universitario Nino Jesus, Madrid
Registry updated 2026-10-06
NCT05748171
A Study to Learn More About the Study Medicine Called Inotuzumab Ozogamicin (InO) in Children (1 to <18 Years) With First Relapse ALL
Trial Treatment · Phase 2 · Pfizer
Hospital Universitari Vall d'Hebron, Barcelona · Hospital Sant Joan De Deu Barcelona, Esplugues de Llobregat · Hospital Infantil Universitario Nino Jesus, Madrid · Hospital Universitario La Paz, Madrid · University Clinical Hospital Virgen De La Arrixaca, Murcia · Universidade De Santiago De Compostela, Santiago De Compostela · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-09-24
2026-525964-17-00
A phase II clinical trial of inotuzumab ozogamicin as prophylaxis for relapse in patients with lymphoblastic leukaemia after allogeneic stem cell haemotopoietic transplantation
Trial Treatment · Phase 2 · Fundacion PETHEMA
Institut Catala d'Oncologia, Badalona · Hospital de la Santa Creu i Sant Pau, Barcelona · Hospital Universitario Donostia, Donostia · Hospital Universitario 12 de Octubre, Madrid · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario Regional de Málaga, Málaga · Complejo Asistencial Universitario de Salamanca, Salamanca · Hospital Universitario Marqués de Valdecilla, Santander · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-09-15
NCT01949129
Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia
Trial Treatment · Phase 2/3 · St. Anna Kinderkrebsforschung
Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca, Barcelona · Hospital de la Santa Creu i Sant Pau, Barcelona · University Clinical Hospital Virgen De La Arrixaca, Murcia · Hospital Universitario Central De Asturias, Oviedo
Registry updated 2026-09-04
NCT03911128
A Treatment Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia
Research · Mats Heyman
Hospital Universitario Dr.Balmis, Alicante · Hospital Universitario de Cruces, Barakaldo · Hospital Universitario San Joan de Déu, Barcelona · Hospital Universitario Vall d'Hebron, Barcelona · Hospital Universitario La Paz, Fuencarral-El Pardo · Hospital Infantil Universitario Nino Jesus, Madrid · Hospital Clínico Universitario Virgen de la Arrixaca, Murcia · Hospital Universitario Son Espases, Palma de Mallorca · Hospital Universitario Marqués de Valdecilla, Santander · Hospital Clínico Universitario de Santiago, Santiago de Compostela · Hospital Universitario Virgen del Rocio, Seville · Hospital Universitario Politécnico La Fe, Valencia · Hospital Universitario Miguel Servet, Zaragoza
Registry updated 2026-08-13
NCT04307576
A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia
Trial Treatment · Phase 3 · Mats Heyman
Hospital Universitario de Cruces, Barakaldo · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Sant Joan De Deu Barcelona, Esplugues de Llobregat · Hospital Infantil Universitario Nino Jesus, Madrid · Hospital Universitario La Paz, Madrid · University Hospital Son Espases, Palma · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital Universitario Y Politecnico La Fe, Valencia · Hospital Universitario Miguel Servet, Zaragoza
Registry updated 2026-08-12
2023-509723-41-01
A Phase I Clinical Trial of CART cell therapy for refractory/ relapsed acute lymphoblastic leukemia with unmet needs in children, adolescents and young adults: feasibility and safety study (REALL_CART)
Trial Treatment · Phase 1 · Fundacion Para La Investigacion Biomedica Del Hospital Universitario La Paz
Hospital Universitario La Paz, Madrid
Registry updated 2026-08-03
NCT04877522
Asciminib Roll-over Study
Trial Treatment · Phase 4 · Novartis Pharmaceuticals
Institut Catala d'Oncologia, Badalona · Hospital Clinic de Barcelona, Barcelona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Universitario Basurto, Bilbao · Institut Catala D'oncologia, L'Hospitalet de Llobregat · Hospital Universitario 12 de Octubre, Madrid · Hospital Universitario de la Princesa, Madrid · Hospital Universitario Ramón y Cajal, Madrid · Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife · Complexo Hospitalario Universitario De Santiago, Santiago de Compostela · Hospital Universitario Virgen De La Macarena, Sevilla · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-07-06
2024-516570-30-00
A PRECISION MEDICINE RANDOMIZED TRIAL FOR PATIENTS WITH RELAPSED OR REFRACTORY T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA BASED ON A FUNCTIONAL APPROACH. ALL-TARGET TRIAL
Trial Treatment · Phase 2 · Centre Hospitalier De Versailles
Institut Catala d'Oncologia, Badalona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Universitario Donostia, Donostia · Hospital Universitario 12 de Octubre, Madrid · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario Virgen de la Victoria, Málaga · Hospital General Universitario Morales Meseguer, Murcia · Hospital Universitario De Salamanca, Salamanca · Hospital Universitario Marqués de Valdecilla, Santander · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-06-08
2023-504694-20-00
Inotuzumab ozogamicin for Acute Lymphoblastic Leukemia
Trial Treatment · Phase 1/2 · Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Hospital Universitari Vall d'Hebron, Barcelona · Sant Joan De Deu Barcelona Hospital, Esplugues De Llobregat · Hospital Infantil Universitario Nino Jesus, Madrid · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-06-04
2024-519966-31-00
Phase I/IIa clinical trial with dose escalation to evaluate safety and efficacy of the infusion of CART84 in relapsed/refractory (R/R) acute myeloid leukemia (AML) and acute lymphoblastic T leukemia patients (T-ALL).
Trial Treatment · Phase 1/2 · Gyala Therapeutics S.L.
Hospital Clinic de Barcelona, Barcelona · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-06-03
2025-522673-11-00
Single-center phase I/IIa study with CART cells produced using the anti-CD19 transposon technique (TranspoCART19) for patients with CD19+ acute lymphoblastic leukemia resistant or refractory to treatment
Trial Treatment · Phase 1/2 · Clinica Universidad De Navarra
Clínica Universidad de navarra, Pamplona
Registry updated 2026-05-22

All Acute lymphoblastic leukaemia trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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