Acute lymphoblastic leukaemia trials in United States

In United States 232 Also abroad 564

232 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome
Where
Seattle
Age
18 years to 75 years
People
30
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT03670966
Phase 2Taking people
Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)
Where
Chicago
Age
18 years and over
People
25
Run by
University of Chicago
See details and how to joinNCT04747912
Phase 2Taking people
Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases
Where
Gainesville
Age
6 months to 39 years
People
20
Run by
University of Florida
See details and how to joinNCT05800210
Phase 2Taking people
Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity
Where
Memphis
Age
18 years and over
People
20
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT07228741
Phase 1/2Taking people
Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase
Where
Charlotte, Cincinnati, Memphis
Age
Up to 21 years
People
42
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT04195347
No phaseTaking people
European Prospective Investigation Into Childhood Cancer
Where
New York
Age
3 years to 21 years
People
1,400
Run by
Columbia University
See details and how to joinNCT05375617
No phaseTaking people
Pharmacogenomics of Asparaginase Induced Hepatotoxicity
Where
Los Angeles
Age
18 years and over
People
500
Run by
University of Southern California
See details and how to joinNCT03568266
Phase 2Taking people
Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies
Where
Seattle
Age
6 months and over
People
60
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT04195633
Phase 1Taking people
Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies
Where
Columbus
Age
2 years and over
People
54
Run by
Sumithira Vasu
See details and how to joinNCT05418088
No phaseTaking people
Virtual Reality-Infused Treadmill Training on Aging-Related Outcomes
Where
Arlington
Age
18 years to 75 years
People
60
Run by
The University of Texas at Arlington
See details and how to joinNCT06727942
Phase 1/2Taking people
Autologous HuCART19 T Cells Manufactured Using the CliniMACS Prodigy Platform for Pediatric B-ALL (huCART19 Prodigy)
Where
Philadelphia
Age
0 years to 29 years
People
115
Run by
Stephan Grupp MD PhD
See details and how to joinNCT05480449
Phase 2Taking people
Blinatumomab, Inotuzumab Ozogamicin, and Combination Chemotherapy as Frontline Therapy in Treating Patients With B Acute Lymphoblastic Leukemia
Where
Houston
Age
14 years and over
People
80
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT02877303
No phaseTaking people
A Registry for People With T-cell Lymphoma
Where
Atlanta, Aurora, Basking Ridge, Boston, Chicago, Columbus, Commack, Duarte, Harrison, Houston, Miami, Middletown, New Haven, New York, Omaha, Philadelphia, Rochester, San Diego, San Francisco, Stanford, St Louis, Tampa, Uniondale
People
1,000
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT05978141
Phase 1Taking people
CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)
Where
Memphis
Age
Up to 21 years
People
108
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT04318678
Phase 1Taking people
CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic Leukemia
Where
Memphis
Age
Up to 21 years
People
30
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT06777979
No phaseTaking people
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
Where
Akron, Albuquerque, Asheville, Atlanta, Baltimore, Birmingham, Boston, Buffalo, Burlington, Charleston, Chicago, Cincinnati, Columbia, Dallas, Detroit, Duarte, Flint, Fort Myers, Fort Worth, Gainesville, Greenville, Hackensack, Hollywood, Honolulu, Houston, Jackson, Jacksonville, Las Vegas, Lebanon, Little Rock, Madera, Milwaukee, New Haven, New Hyde Park, New Orleans, Oakland, Oak Lawn, Oklahoma City, Orlando, Palo Alto, Peoria, Philadelphia, Phoenix, Portland, Providence, Richmond, Rochester, San Antonio, San Diego, Scarborough, Seattle, Spokane, St Louis, Stony Brook, St. Petersburg, Syracuse, Tampa, Tucson, West Palm Beach, Winston-Salem
People
420 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT01790152
Phase 1Taking people
HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant
Where
Seattle
Age
Up to 80 years
People
24
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT03326921
Phase 1Taking people
Novel Unedited Allo Cell Therapy For High Risk T-Cell Malignancies Using CD7-Specific Car T Cells
Where
Houston
Age
Up to 75 years
People
27
Run by
Baylor College of Medicine
See details and how to joinNCT07220993
Phase 1Taking people
Evaluating the Safety and Efficacy of DuoCAR20.19.22-D95 in Adult Patients With Relapsed or Refractory B-cell Malignancies
Where
Westwood
Age
18 years and over
People
54
Run by
University of Kansas Medical Center
See details and how to joinNCT06879340
Phase 2Taking people
Cord Blood Transplantation in Children and Young Adults With Blood Cancer
Where
New York
Age
Up to 26 years
People
71
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT07566377
No phaseTaking people
MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing
Where
Milwaukee
Age
0 years to 25 years
People
40
Run by
Medical College of Wisconsin
See details and how to joinNCT05794880
Phase 1Taking people
Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.
Where
Boston, Chapel Hill, Chicago, Cincinnati, Columbus, Houston, Salt Lake City
Age
13 years and over
People
100
Run by
Newave Pharmaceutical Inc
See details and how to joinNCT04771572
Phase 3Taking people
A Study of Olverembatinib in Patients With Newly Diagnosed Ph+ ALL (POLARIS-1)
Where
Augusta, Birmingham, Duarte, Hackensack, Houston, Indianapolis, Lexington, Los Angeles, Miami, Morgantown, New Brunswick, Seattle, Stony Brook, The Bronx
Age
18 years and over
People
350 worldwide
Run by
Ascentage Pharma Group Inc.
See details and how to joinNCT06051409 · EU 2024-511496-14-00
No phaseTaking people
CAR T-cell Long-Term Follow-Up, Quality of Life and Adverse Reactions
Where
Memphis
People
80
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT07048535
Early phase 1Taking people
Allogeneic CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Vaccine After Matched Related Donor Hematopoietic Cell Transplant for the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia
Where
Duarte
Age
18 years and over
People
15
Run by
City of Hope Medical Center
See details and how to joinNCT06735690