Acute myeloid leukaemia trials in France

In France 87 Also abroad 763

87 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 14 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Study of the Relationship Between the Pharmacokinetics (PK) and Pharmacodynamics of Venetoclax in Patients With Acute Myeloblastic Leukemia
Where
Bourgoin, Grenoble, Lyon, Saint-Etienne, Villefranche-sur-Saône
Age
18 years and over
People
100
Run by
Centre Leon Berard
See details and how to joinNCT07243483
Phase 3Taking people
Phase III Study Comparing GVHD Prophylaxis With ATG-thymoglobulin to ATLG-grafalon in Elderly Patients With Acute Myeloid Leukemia or Myelodysplasic Syndrome and Receiving an Allogeneic Hematopoietic Stem Cell Transplantation With a 10/10 HLA Matched Unrelated Donor
Where
Amiens, Angers, Besançon, Bordeaux, Brest, Caen, Clermont-Ferrand, Créteil, Grenoble, Lille, Limoges, Lyon, Marseille, Montpellier, Nancy, Nantes, Nice, Paris, Poitiers, Rennes, Saint-Etienne, Strasbourg, Toulouse, Tours, Villejuif
Age
50 years to 70 years
People
324
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT06083129
Phase 2Taking people
CPX-351 vs Intensive Chemotherapy in Patients With de Novo Intermediate or Adverse Risk AML Stratified by Genomics
Where
Amiens, Angers, Avignon, Besancon Cedex, Béziers, Bobigny Cedex, Caen Cedex 9, Clamart, Clermont Ferrand Cedex 1, Corbeil-Essonnes, Creteil Cedex, Le Chesnay, Lille Cedex, Limoges, Marseille, Marseille Cedex 05, Metz Cedex 03, Mulhouse, Nantes, Nice, Nice Cedex 2, Nimes Cedex 9, Orleans Cedex 2, Paris, Paris Cedex 12, Paris Cedex 13, Pessac, Pierre-Bénite, Roubaix, Rouen, Saint-Etienne Cedex 2, Toulouse Cedex 9, Tours, Villejuif
Age
18 years and over
People
248
Run by
Centre Hospitalier Universitaire de Nice
See details and how to joinNCT05260528 · EU 2022-500295-60-00
Phase 1/2Taking people
A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
Where
Angers, Bobigny, Le Mans, Lille, Limoges, Lyon, Marseille, Nantes, Nice, Paris, Talence, Villejuif
Age
12 years and over
People
606 worldwide
Run by
Sumitomo Pharma America, Inc.
See details and how to joinNCT04988555
Phase 1Taking people
First-In-Human study evaluating the Safety of administration of ABD-3001 to Patients with Relapsed/Refractory Acute Myeloid Leukemia or High/Very-high Risk Myelodysplastic Syndromes
Where
Marseille, Montpellier Cedex 5, Nice, Paris, Pierre-Bénite
Age
18 years and over
People
61
Run by
Advanced Biodesign
See details and how to join2024-518813-24-00
Phase 2Taking people
De-Escalation Study Evaluating Venetoclax and Azacitidine Discontinuation in AML Responding Patients
Where
Marseille, Nantes Cedex 1, Rennes, Talence, Toulouse Cedex 9
Age
18 years and over
People
50
Run by
Institut Paoli-Calmettes
See details and how to joinNCT06557421 · EU 2024-514112-28-00
Phase 2Not yet taking people in France
Study Evaluating the Efficacy and Safety of the Addition of Ivosidenib to Oral Azacitidine (Onureg®) in Patients Over 55 With Acute Myeloid Leukemia (AML) and IDH1 Mutation, in Complete Remission After Intensive Chemotherapy.
Where
Angers, Bayonne, Besançon, Clamart, Créteil, Grenoble, Lille, Limoges, Nantes, Nîmes, Paris, Perpignan, Pessac, Pierre-Bénite, Rennes, Rouen, Toulouse, Tours, Vandœuvre-lès-Nancy, Villejuif
Age
55 years and over
People
60
Run by
French Innovative Leukemia Organisation
See details and how to joinNCT07463768
No phaseTaking people
Evaluation of Chemotherapy-induced Cognitive Disorders During the Treatment of Hematological Malignancies
Where
Angers
Age
18 years and over
People
120
Run by
University Hospital, Angers
See details and how to joinNCT07147621
Phase 1Not yet taking people in France
Study With Tocilizumab in Combination With Venetoclax and Azacitidine Chemotherapy in Patients With Acute Myeloid Leukemia
Where
Nantes
Age
18 years and over
People
12
Run by
Nantes University Hospital
See details and how to joinNCT07392814 · EU 2025-524725-41-00
No phaseTaking people
Quality of Life-Guided Transfusion in Refractory MDS or AML
Where
Nice
Age
18 years and over
People
52
Run by
Centre Hospitalier Universitaire de Nice
See details and how to joinNCT07328191
No phaseTaking people
Determination of Epigenetic Markers of Acute Myeloblastic Leukemia in Elderly Patients
Where
Mulhouse
Age
60 years and over
People
30
Run by
Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
See details and how to joinNCT07250217
No phaseNot yet taking people in France
Effect of Hypnosis and Virtual Reality on Anxiety During Treatment for Acute Myeloid Leukemia
Where
Toulouse
Age
18 years and over
People
99
Run by
University Hospital, Toulouse
See details and how to joinNCT07386392
Phase 2Taking people
Study Comparing the Efficacy of 2 RIC Regimens (Clofarabine vs Fludarabine) in Adults With AML Eligible to Allo-SCT
Where
Amiens, Angers, Besançon, Bordeaux, Brest, Caen, Clermont-Ferrand, Créteil, Grenoble, Lille, Limoges, Lyon, Marseille, Montpellier, Nancy, Nantes, Paris, Poitiers, Rennes, Saint-Etienne, Toulouse
Age
18 years to 99 years
People
302
Run by
Nantes University Hospital
See details and how to joinNCT05917405
Phase 4Taking people
PTX3-targeted Antifungal Prophylaxis
Where
Créteil Cedex
Age
18 years and over
People
410 worldwide
Run by
Bochud Pierre-Yves
See details and how to joinNCT03828773 · EU 2024-517211-79-00
No phaseTaking people
Study of Families With an Hemopathies Predisposition Related to the DDX41 Gene.
Where
Bordeaux, Limoges, Marseille, Montpellier, Toulouse
Age
18 years and over
People
910
Run by
Institut Claudius Regaud
See details and how to joinNCT06022016
Phase 1Taking people
Study Investigating the Safety of CD19 CAR-T Cells in Relapsed/Refractory AML Expressing CD19
Where
Lille
Age
18 years and over
People
5
Run by
University Hospital, Lille
See details and how to joinNCT06649227 · EU 2023-509212-29-01
No phaseTaking people
OBServatory of Compassionate Use of IVOsidenib in France for Patients With Acute Myeloid Leukemia
Where
Amiens, Angers, Bayonne, Besançon, Clermont-Ferrand, Créteil, Dunkirk, Grenoble, Le Mans, Lyon, Marseille, Meaux, Montpellier, Mulhouse, Nantes, Nice, Orléans, Paris, Pessac, Strasbourg, Toulouse
Age
18 years and over
People
250
Run by
French Innovative Leukemia Organisation
See details and how to joinNCT06377579
No phaseTaking people
Study of the Medullary Microenvironment in Acute Childhood Leukemia
Where
Tours
Age
1 year to 15 years
People
40
Run by
University Hospital, Tours
See details and how to joinNCT05792007
No phaseTaking people
Prospective Non-interventional Study of Adult Patients With Acute Myeloid Leukemia (AML)
Where
Amiens, Argenteuil, Bobigny, Caen, Clamart, Corbeil-Essonnes, Créteil, Dijon, Dunkirk, Le Chesnay, Lens, Lille, Limoges, Marseille, Meaux, Nice, Paris, Pierre-Bénite, Pontoise, Roubaix, Rouen, Saint-Cloud, Saint-Quentin, Valenciennes, Villejuif
Age
18 years and over
People
5,000
Run by
Acute Leukemia French Association
See details and how to joinNCT04777916
Phase 1/2Suspended
AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Where
Marseille
Age
18 years and over
People
78 worldwide
Run by
AB Science
See details and how to joinNCT05211570 · EU 2024-516641-39-00
Phase 1/2Not yet taking people in France
An Adaptive Open-label Multicentre Phase 1/2 Trial, to Determine the Recommended Phase 2 Dose of CCTx-001, and to Assess Safety, Tolerability, and Clinical Activity in Patients With Relapsed/Refractory Acute Myeloid Leukaemia
Where
Besançon, Paris
Age
18 years and over
People
143 worldwide
Run by
Advesya SAS
See details and how to joinNCT06281847
Phase 3Not yet taking people in France
Ivosidenib and Azacitidine With or Without Venetoclax in Adult Patients With Newly Diagnosed IDH1-Mutated AML or MDS/AML Considered Ineligible for Intensive Chemotherapy
Where
Angers, Bordeaux, Caen, Créteil, Grenoble, Lille, Lyon, Montpellier, Nantes, Nice, Rennes, Rouen, Saint-Etienne, Versailles
Age
18 years and over
People
227 worldwide
Run by
Stichting Hemato-Oncologie voor Volwassenen Nederland
See details and how to joinNCT07075016
Phase 3Taking people
A Multicenter Trial Evaluating Efficacy and Safety of A Reduced Venetoclax Exposure To Seven Days Versus Standard Continuous Venetoclax Exposure Combined With Azacitidine in Treatment Naïve Subjects With Acute Myeloid Leukemia Who Are Ineligible for Intensive Induction
Where
Amiens Cedex 1, Bayonne, Bobigny, Le Chesnay Rocquencourt, Mulhouse, Paris, Perpignan Cedex, Toulouse, Vandoeuvre Les Nancy Cedex, Villejuif
Age
70 years and over
People
262 worldwide
Run by
Gustave Roussy, Cancer Campus, Grand Paris
See details and how to joinNCT07082452 · EU 2025-521634-29-00
No phaseNot yet taking people in France
Study of Management and Prognosis of Patients With Acute Myeloblastic Leukemia in Saint-Antoine Hospital
Where
Paris
Age
18 years and over
People
750
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT05558943
Phase 2Active, not recruiting
Study Investigating the Efficacy and Safety of the Addition of Oral-azacitidine to Salvage Treatment by Gilteritinib in Subjects ≥18 Years of Age With Relapsed/Refractory FLT3-mutated Acute Myeloid Leukemia
Where
Amiens, Angers Cedex 9, Bayonne, Clamart, Clermont-Ferrand, Creteil Cedex, Grenoble Cedex 9, Le Chesnay Rocquencourt, Lille, Limoges, Marseille, Nantes, Paris, Pessac, Pierre-Bénite, Rennes Cedex 9, Rouen, Strasbourg, Strasbourg Cedex 2, Toulouse, Vandoeuvre Les Nancy
Age
18 years and over
People
33
Run by
French Innovative Leukemia Organisation
See details and how to joinNCT06022003 · EU 2022-501372-25-00