Acute myeloid leukemia trials in Spain

In Spain 62 Also abroad 761

62 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 2/3Taking people
A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
Where
Badalona, Barcelona, Cáceres, Girona, Granada, L'Hospitalet de Llobregat, Madrid, Málaga, Oviedo, Pamplona, Salamanca, Valencia
Age
18 years and over
People
316 worldwide
Run by
Taiho Oncology, Inc.
See details and how to joinNCT04256317 · EU 2024-515098-93-00
Phase 2Taking people
A Multicenter, Open-Label, Dose-Finding Clinical Trial to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Efficacy of RVU120 in Combination with Venetoclax in Participants with Acute Myeloid Leukemia Who Failed Prior Therapy with Venetoclax and a Hypomethylating Agent (RIVER-81)
Where
Barcelona, Cáceres, Madrid, Málaga, Pamplona, Sevilla, Valencia
Age
18 years and over
People
191 worldwide
Run by
Ryvu Therapeutics S.A.
See details and how to join2023-505911-19-00 · EU 2023-505911-19-00
Phase 3Taking people
CHIP-AML22 Master protocol: Protocol for the treatment of children and adolescents with Acute Myeloid Leukemia (AML)
Where
Alicante, Badajoz, Barakaldo, Barcelona, Esplugues De Llobregat, Las Palmas de Gran Canaria, Madrid, Málaga, Murcia, Oviedo, Palma, Santander, Santiago de Compostela, Sevilla, Valencia, Zaragoza
Age
Up to 64 years
People
675 worldwide
Run by
Prinses Maxima Centrum voor Kinderoncologie B.V.
See details and how to join2023-504999-25-00 · EU 2023-504999-25-00
Phase 2Taking people
Oral Decitabine Plus Ivosidenib as First Line for Older/Unfit Adult AML Patients
Where
Albacete, Alicante, Burgos, Cáceres, Córdoba, Las Palmas, Las Palmas de Gran Canaria, Lugo, Madrid, Málaga, Seville, Valencia
Age
18 years and over
People
50 worldwide
Run by
PETHEMA Foundation
See details and how to joinNCT07507760
Phase 2Taking people
Safety and Efficacy of RVU120 Combined With Venetoclax for Treatment of Relapsed/Refractory AML
Where
Barcelona, Cáceres, Madrid, Málaga, Pamplona, Seville, Valencia
Age
18 years and over
People
98 worldwide
Run by
Ryvu Therapeutics SA
See details and how to joinNCT06191263
Phase 2Enrolling by invitation
RVU120 Rollover Study
Where
Pamplona
Age
18 years and over
People
14 worldwide
Run by
Ryvu Therapeutics SA
See details and how to joinNCT06987058 · EU 2025-521673-14-00
Phase 2Taking people
(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
Where
Barcelona, Madrid
Age
18 years and over
People
140 worldwide
Run by
Cogent Biosciences, Inc.
See details and how to joinNCT04996875 · EU 2024-511407-42-00
Phase 2Taking people
A study to evaluate the safety and efficacy of oral decitabine plus ivosidenib in newly diagnosed adult patients with acute myeloid leukemia older than 60 years and/or inelegible for standard induction chemotherapy
Where
Albacete, Alcalá de Henares, Alicante, Burgos, Cáceres, Córdoba, Las Palmas De Gran Canaria, Lugo, Madrid, Málaga, San Cristóbal de La Laguna, Sevilla, Valencia
Age
18 years and over
People
62 worldwide
Run by
Fundacion PETHEMA
See details and how to join2025-523238-17-00 · EU 2025-523238-17-00
Phase 1/2Taking people
A Study of BGB-11417 in Participants With Myeloid Malignancies
Where
Barcelona, Salamanca, Sevilla, Valencia
Age
18 years and over
People
260 worldwide
Run by
BeOne Medicines
See details and how to joinNCT04771130 · EU 2023-508881-14-00
Phase 3Taking people
Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML
Where
Badalona, Barcelona, Girona, L'Hospitalet de Llobregat, Lleida, Madrid, Palma, Tarragona, Terrassa, Valencia
Age
18 years and over
People
448 worldwide
Run by
Stichting Hemato-Oncologie voor Volwassenen Nederland
See details and how to joinNCT06652438 · EU 2024-512733-32-00
Phase 1Taking people
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Where
Barcelona, Oviedo, Sevilla, Valencia
Age
18 years and over
People
171 worldwide
Run by
Kura Oncology, Inc.
See details and how to joinNCT06001788 · EU 2023-510288-37-00
Phase 2/3Taking people
L-Annamycin for Injection in Combination With Cytarabine Injection as Second Line Therapy for Remission Induction in Adult Subjects With Refractory/Relapsed AML
Where
Badalona, Madrid, Oviedo, Valencia
Age
18 years to 80 years
People
312 worldwide
Run by
Moleculin Biotech, Inc.
See details and how to joinNCT06788756 · EU 2024-518359-47-00
Phase 2Enrolling by invitation
A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)
Where
Barcelona, Lleida, Logroño, Madrid, Murcia
Age
18 years and over
People
332 worldwide
Run by
Taiho Oncology, Inc.
See details and how to joinNCT04093570 · EU 2024-516293-29-01
Phase 1Taking people
A Study to Assess Adverse Events and How Pivekimab Sunirine Moves Through the Body of Pediatric Patients with Relapsed or Refractory Acute Myeloid Leukemia (AML)
Where
Esplugues de Llobregat, Madrid
Age
Up to 17 years
People
18 worldwide
Run by
AbbVie Deutschland GmbH & Co. KG
See details and how to join2024-520125-36-00 · EU 2024-520125-36-00
Phase 1/2Not yet taking people in Spain
A Study to Evaluate S241656 Alone or in Combination in Participants With Selected Myeloid Malignancies
Where
Barcelona, Madrid, Pamplona, Valencia
Age
18 years and over
People
64 worldwide
Run by
Servier
See details and how to joinNCT07719348 · EU 2025-525128-88-00
Phase 1/2Taking people
Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies
Where
Badalona, Barcelona, Madrid, Pamplona, Valencia
Age
18 years and over
People
250 worldwide
Run by
CellCentric Ltd.
See details and how to joinNCT04068597
Phase 2Taking people
A Phase II, Open-Label Randomized Study of Intravenous Tambiciclib in Combination with the Standard of care Venetoclax and Azacitidine in Patients with Newly Diagnosed AML Who Failed to Achieve at Least MLFS After the First Two Cycles of Treatment with Venetoclax and Azacitidine Alone
Where
Albacete, Alicante, Valencia
Age
18 years and over
People
40 worldwide
Run by
Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori IRST S.r.l.
See details and how to join2025-524308-31-00 · EU 2025-524308-31-00
Phase 1/2Taking people
Phase I/IIa clinical trial with dose escalation to evaluate safety and efficacy of the infusion of CART84 in relapsed/refractory (R/R) acute myeloid leukemia (AML) and acute lymphoblastic T leukemia patients (T-ALL).
Where
Barcelona, Valencia
Age
18 years and over
People
39
Run by
Gyala Therapeutics S.L.
See details and how to join2024-519966-31-00 · EU 2024-519966-31-00
Phase 1Taking people
Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairment
Where
Barcelona, Lleida, Logrono, Madrid, Murcia, Valencia
Age
18 years and over
People
18 worldwide
Run by
Taiho Oncology, Inc.
See details and how to joinNCT04953897 · EU 2024-516291-16-00
Phase 1Taking people
Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment
Where
Barcelona, Lleida, Logrono, Madrid, Murcia, Valencia
Age
18 years and over
People
27 worldwide
Run by
Taiho Oncology, Inc.
See details and how to joinNCT04953910 · EU 2024-516292-33-00
Phase 3Taking people
An Open-label Phase 3b Study of Ivosidenib in Combination With Azacitidine in Adult Patients Newly Diagnosed With IDH1m Acute Myeloid Leukemia (AML) Ineligible for Intensive Induction Chemotherapy.
Where
Badalona, Barcelona, Burgos, Cáceres, Las Palmas de Gran Canaria, Madrid, Terrassa, Valencia
Age
18 years and over
People
245 worldwide
Run by
Servier Affaires Médicales
See details and how to joinNCT05907057 · EU 2022-501709-11-00
Phase 1/2Taking people
A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
Where
Albacete, Barcelona, Cáceres, Las Palmas, Madrid, Oviedo, Salamanca, Santander, Santiago de Compostela, Valencia
Age
12 years and over
People
606 worldwide
Run by
Sumitomo Pharma America, Inc.
See details and how to joinNCT04988555
Phase 1/2Taking people
Safety and Efficacy of GYA01 (CART84) in Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) and Acute Lymphoblastic T Leukemia Patients (T-ALL).
Where
Barcelona, Valencia
Age
18 years and over
People
33
Run by
Gyala Therapeutics
See details and how to joinNCT07471789
Phase 3Taking people
A Pivotal Study of APG-2575 (Lisaftoclax) Combined With Azacitidine in the Treatment of Acute Myeloid Leukemia
Where
Badalona, Palma
Age
18 years and over
People
486 worldwide
Run by
Ascentage Pharma Group Inc.
See details and how to joinNCT06389292 · EU 2024-516436-10-00
Phase 2Taking people
Preparation for bone marrow transplant through the combined use of chemo and radiotherapy (intensive or myeloablative: eliminates stem cells)
Where
Sevilla
Age
18 years and over
People
49
Run by
Fundacion Publica Andaluza Para La Gestion De La Investigacion En Salud De Sevilla
See details and how to join2024-514484-25-00 · EU 2024-514484-25-00