Acute myeloid leukaemia trials in United States

In United States 334 Also abroad 763

334 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)
Where
Anaconda, Baton Rouge, Bemidji, Billings, Bismarck, Bloomington, Brighton, Buffalo, Canton, Carthage, Chelsea, Chicago, City of Saint Peters, Coeur d'Alene, Columbus, Creve Coeur, Crown Point, Decatur, Eureka, Fargo, Galesburg, Great Falls, Kalispell, Kewanee, La Crosse, Lexington, Livonia, Macomb, Milwaukee, Missoula, New Lenox, O'Fallon, Oklahoma City, Orland Park, Ottawa, Pekin, Peoria, Peru, Philadelphia, Pontiac, Post Falls, Princeton, Providence, Rochester, Salt Lake City, Sandpoint, Sioux Falls, Springfield, St Louis, Washington, Wilkes-Barre, Ypsilanti
Age
60 years and over
People
126 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT07437950
Phase 1Taking people
A Study of CHM-029 in Participants With NPM1 Mutated, KMT2A or NUP98 Rearranged AML
Where
Duarte, Grand Rapids, Nashville, New Haven, New York
Age
18 years and over
People
40 worldwide
Run by
Charm Therapeutics
See details and how to joinNCT07751991 · EU 2026-526409-14-00
Phase 4Taking people
Oral Azacitidine in Transplant-Eligible Patients With Acute Myeloid Leukemia (AML) Suffering From Health-Inequality
Where
Richmond
Age
18 years and over
People
12
Run by
Virginia Commonwealth University
See details and how to joinNCT06370000
Phase 2Not yet taking people in United States
Revumenib, Azacitidine, and VENetoclax in Newly Diagnosed KMT2A-Rearranged AML
Where
Chapel Hill
Age
18 years to 65 years
People
88
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT07605949
No phaseTaking people
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Where
Aberdeen, Aitkin, Akron, Albert Lea, Albuquerque, Allentown, Alma, Alpena, Alton, Amarillo, Ames, Anaconda, Anchorage, Anderson, Ankeny, Ann Arbor, Antigo, Appleton, Arroyo Grande, Asheville, Ashland, Augusta, Aurora, Aventura, Baker City, Bakersfield, Ballwin, Baltimore, Baraboo, Barberton, Bardstown, Barrington, Baton Rouge, Battle Creek, Baxter, Beavercreek, Belfast, Bellingham, Belpre, Bemidji, Bend, Berlin, Bethesda, Bethlehem, Biddeford, Billings, Bismarck, Bloomington, Boardman, Boise, Bolivar, Bonita Springs, Boone, Boulder, Bozeman, Brainerd, Branson, Braselton, Brewer, Brighton, Brownstown, Brunswick, Bryan, Burbank, Burien, Burlington, Burnsville, Caldwell, Cambridge, Canton, Cape Girardeau, Carbondale, Carmichael, Caro, Carson City, Carterville, Carthage, Cary, Cedar Rapids, Centennial, Centerville, Centralia, Chaska, Chelsea, Chesapeake, Chesterfield, Cheyenne, Chicago, Chillicothe, Cincinnati, Clackamas, Clarkston, Clearwater, Clinton, Clinton Township, Clive, Clyde, Cody, Coeur d'Alene, Colorado Springs, Columbia, Columbus, Concord, Coon Rapids, Coos Bay, Corbin, Council Bluffs, Creston, Crosslake, Crystal Lake, Cudahy, Danville, Dayton, Dearborn, Decatur, Deerfield Beach, Deer River, Delaware, Denver, Des Moines, Detroit, Detroit Lakes, Dixon, Downers Grove, Dublin, Duluth, Durango, Durham, East China Township, Easton, East Stroudsburg, Eau Claire, Edgewood, Edina, Edmonds, Effingham, Elgin, Elk Grove, Elmhurst, Elmira, Ely, Emeryville, Emmett, Englewood, Enumclaw, Eureka, Everett, Evergreen Park, Fairbanks, Fargo, Farmington, Farmington Hills, Federal Way, Findlay, Fishersville, Flint, Florence, Fond du Lac, Fort Collins, Fort Dodge, Fort Lauderdale, Fort Myers, Fort Smith, Fort Thomas, Fosston, Franklin, Freehold, Fridley, Fruitland, Gaffney, Gahanna, Gainesville, Galesburg, Garden City, Garner, Georgetown, Germantown, Gladwin, Glen Burnie, Glens Falls, Goldsboro, Grafton, Grand Forks, Grand Island, Grand Rapids, Great Bend, Great Falls, Greeley, Green Bay, Greenville, Greenwood, Greer, Grosse Pointe Woods, Grove City, Hackettstown, Harvey, Havre, Hayward, Hazel Crest, Hazleton, Helena, Henderson, Hendersonville, Hibbing, Hood River, Houma, Houston, Huntington, International Falls, Issaquah, Jackson, Jacksonville, Jamaica, Jamaica Plain, Jamestown, Janesville, Jefferson, Jefferson City, Joplin, Kalamazoo, Kalispell, Kansas City, Kearney, Kennewick, Kenosha, Kettering, Kewanee, Kingman, Lacey, La Crosse, Lakeland, Lakewood, Lancaster, Lansing, Laredo, Las Cruces, Las Vegas, Leavenworth, Lewisburg, Lexington, Libertyville, Lima, Lincoln, Little Rock, Littleton, Livonia, Loma Linda, London, Lone Tree, Long Beach, Longmont, Longview, Loveland, Macomb, Madison, Manchester, Mankato, Mansfield, Maple Grove, Maplewood, Marietta, Marinette, Marion, Marlette, Marrero, Marshalltown, Martinez, Marysville, Mattoon, Meadowbrook, Mechanicsville, Medford, Medina, Merced, Meridian, Metairie, Miami Beach, Midland, Midlothian, Milwaukee, Minneapolis, Minot, Missoula, Moline, Monticello, Moose Lake, Morristown, Mount Pleasant, Mount Sterling, Mount Vernon, Mukwonago, Mullica Hill, Murrells Inlet, Muskegon, Nags Head, Nampa, Napa, Neenah, New Albany, Newark, Newberg, New Brunswick, New London, New Orleans, New Richmond, Newton, New Ulm, New York, Niles, Norfolk, Normal, Norton Shores, Novi, Oakland, Oak Lawn, Ocean Pines, Oconomowoc, Oconto Falls, O'Fallon, Oklahoma City, Olney, Omaha, Ontario, Oregon City, Osage Beach, Oshkosh, Ottawa, Paducah, Pahrump, Papillion, Parker, Park Rapids, Park Ridge, Pekin, Pennington, Peoria, Pequot Lakes, Perrysburg, Peru, Phoenix, Phoenixville, Pine River, Pittsburg, Plant City, Pompton, Pontiac, Portland, Portsmouth, Port Townsend, Post Falls, Pottstown, Princeton, Providence, Pueblo, Racine, Raleigh, Rancho Mirage, Randallstown, Reading, Redmond, Reed City, Reno, Renton, Rhinelander, Richmond, Rio Rancho, Robbinsdale, Rockford, Rocklin, Rockport, Rolla, Royal Oak, Sacramento, Safety Harbor, Saginaw, Saint Cloud, Sainte Genevieve, Saint Joseph, Saint Louis Park, Saint Paul, Salisbury, San Antonio, Sandpoint, Sandstone, Sanford, San Luis Obispo, Santa Cruz, Santa Maria, Santa Rosa, Savannah, Scarborough, Seattle, Sedro-Woolley, Shakopee, Shawano, Sheboygan, Shelton, Sheridan, Silverdale, Sioux Falls, Southfield, South Portland, Spartanburg, Spokane, Spooner, Springfield, Staples, Sterling Heights, Stevens Point, St. Helena, Stillwater, St Louis, Stockton, Stony Brook, St. Petersburg, Sturgeon Bay, Sullivan, Summit, Superior, Tacoma, Tampa, Tawas City, Thief River Falls, Thornton, Tifton, Toledo, Topeka, Towson, Traverse City, Troy, Twin Falls, Two Rivers, Union, Urbana, Vancouver, Vineland, Virginia, Virginia Beach, Waconia, Walla Walla, Walnut Creek, Warren, Warwick, Washington, Washington D.C., Waukee, Waukesha, Waupaca, Wausau, Wauwatosa, Weaverville, West Allis, West Bloomfield, West Branch, West Columbia, West Des Moines, Westerville, West Haven, Westminster, West Reading, Wichita, Wilkes-Barre, Willmar, Wilmington, Winter Haven, Wisconsin Rapids, Woodbury, Woodland, Worthington, Wyandotte, Wyoming, Yakima, Yelm, Yorkville, Youngstown, Ypsilanti, Zanesville
Age
40 years to 75 years
People
2,900
Run by
Alliance for Clinical Trials in Oncology
See details and how to joinNCT05334069
Phase 2Taking people
Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial)
Where
Albuquerque, Anaconda, Baton Rouge, Bellevue, Billings, Birmingham, Boiling Springs, Boston, Bozeman, Brighton, Buffalo, Canton, Chelsea, Chicago, City of Saint Peters, Coeur d'Alene, Collierville, Columbus, Creve Coeur, Crown Point, Danville, Durham, Easley, Edmonds, Fairway, Great Falls, Greenville, Greer, Grenada, Issaquah, Kalispell, Kansas City, La Crosse, La Jolla, Lexington, Livonia, Louisville, Memphis, Menomonee Falls, Milwaukee, Missoula, New Albany, New Berlin, New Lenox, Oak Creek, Oklahoma City, Omaha, Orland Park, Overland Park, Oxford, Pembroke Pines, Pontiac, Post Falls, Providence, Richmond, Rochester, Salt Lake City, Sandpoint, Seattle, Seneca, Southhaven, St Louis, Syracuse, The Bronx, West Bend, Westwood, Wilkes-Barre, Ypsilanti
Age
18 years to 59 years
People
162 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06917911
Phase 2Taking people
Olutasidenib in Relapsed IDH1 Mutated AML Patients Who Have Previously Received Venetoclax
Where
Winston-Salem
Age
18 years and over
People
25
Run by
Timothy Pardee
See details and how to joinNCT07471841
Phase 1Taking people
Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...
Where
Bethesda
Age
3 years to 35 years
People
54
Run by
National Cancer Institute (NCI)
See details and how to joinNCT02390752
Phase 1Taking people
Study of C6 Ceramide NanoLiposome (CNL) in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Where
Charlottesville
Age
18 years and over
People
15
Run by
Keystone Nano, Inc
See details and how to joinNCT04716452
Phase 1/2Taking people
A Phase I/II Study of Gilteritinib and Momelotinib for Patients With Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia
Where
Houston
Age
18 years and over
People
40
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT06235801
Phase 1Taking people
Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes
Where
Atlanta, Baltimore, Basking Ridge, Boston, Chicago, City of Saint Peters, Commack, Creve Coeur, Crown Point, Harrison, Middletown, Montvale, New Brunswick, New Haven, New Lenox, New York, Orland Park, St Louis, Uniondale, Winston-Salem
Age
18 years and over
People
54
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06484062
Phase 3Taking people
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
Where
Aurora, Baton Rouge, Bethesda, Birmingham, Boston, Buffalo, Canton, Centerville, Charlotte, Chicago, Cincinnati, Cleveland, Dallas, Detroit, Duarte, Fort Myers, Goodyear, Hackensack, Houston, Irvine, Jupiter, Knoxville, Lebanon, Lexington, Little Rock, Louisville, Nashville, Newark, New York, Niles, Orlando, Pembroke Pines, Philadelphia, Pittsburgh, Portland, Richmond, Rochester, Salt Lake City, Seattle, South Portland, St Louis, Tampa, The Bronx, Tucson, Tyler, Weston, Winston-Salem, Ypsilanti
Age
18 years and over
People
600 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06852222 · EU 2024-520154-38-00
Phase 2Taking people
Personalized NK Cell Therapy in CBT
Where
Houston
Age
15 years to 80 years
People
100
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT02727803
Phase 1/2Taking people
Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia
Where
Houston
Age
18 years and over
People
116
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT03214562
Phase 2Taking people
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
Where
‘Aiea, Albany, Albuquerque, Allentown, Anaconda, Ankeny, Ann Arbor, Appleton, Ashland, Augusta, Aurora, Baltimore, Barrington, Basking Ridge, Baton Rouge, Bellevue, Bemidji, Berkeley, Bethesda, Billings, Birmingham, Bismarck, Bloomington, Boiling Springs, Boise, Boston, Bozeman, Brighton, Brunswick, Buffalo, Burlington, Caldwell, Camden, Canton, Carthage, Chapel Hill, Charleston, Charlotte, Charlottesville, Chelsea, Chicago, City of Saint Peters, Cleveland, Clinton Township, Clive, Coeur d'Alene, Collierville, Columbus, Commack, Coon Rapids, Creve Coeur, Crystal Lake, Cudahy, Danville, Decatur, Deer River, DeKalb, Des Moines, Detroit, Dixon, Downers Grove, Dublin, Duluth, Durham, Easley, Eau Claire, Edina, Edmonds, Effingham, Elgin, Eureka, Evanston, Fairfax, Fairway, Falls Church, Fargo, Farmington, Farmington Hills, Flint, Fremont, Fresno, Fruitland, Gainesville, Galesburg, Geneva, Germantown, Glenview, Grafton, Grayslake, Great Falls, Green Bay, Greenville, Greer, Grenada, Harvey, Hays, Hazel Crest, Hershey, Hibbing, Highland Park, Hines, Honolulu, Houston, Indianapolis, Iowa City, Irvine, Issaquah, Jackson, Jacksonville, Janesville, Kalispell, Kansas City, Kenosha, Kewanee, Knoxville, La Crosse, Lake Forest, Lake Success, Las Vegas, Lawrence, Lebanon, Lee's Summit, Lewistown, Lexington, Libertyville, Little Rock, Livingston, Livonia, Long Beach, Long Branch, Los Angeles, Louisville, Macomb, Madison, Manhasset, Marinette, Marshfield, Mattoon, Maywood, Memphis, Menomonee Falls, Meridian, Miami, Middletown, Milwaukee, Minneapolis, Minocqua, Missoula, Modesto, Montvale, Mukwonago, Nampa, New Albany, Newberg, New Berlin, New Brunswick, New Haven, New York, Novi, Oak Creek, Oakland, Oak Lawn, Oconomowoc, Oconto Falls, O'Fallon, Oklahoma City, Olathe, Omaha, Ontario, Orange, Oregon City, Orland Park, Oshkosh, Ottawa, Overland Park, Oxford, Palos Heights, Paramus, Park Ridge, Pekin, Pella, Pembroke Pines, Peoria, Peru, Philadelphia, Phoenix, Pittsburgh, Pontiac, Portland, Post Falls, Princeton, Providence, Racine, Reno, Rice Lake, Richmond, Ridgewood, Rochester, Roseville, Ruskin, Sacramento, Sainte Genevieve, Saint Joseph, Saint Louis Park, Saint Paul, Salina, Salt Lake City, Sandpoint, San Francisco, San Jose, San Leandro, San Rafael, Santa Clara, Santa Rosa, Scarborough, Seattle, Seneca, Sheboygan, Sioux Falls, Southhaven, South Portland, South San Francisco, Springfield, Stevens Point, St Louis, Stony Brook, Sturgeon Bay, Sullivan, Summit, Syracuse, Tampa, The Bronx, Toms River, Topeka, Tucson, Two Rivers, Uniondale, Urbana, Vallejo, Virginia, Walnut Creek, Warrenville, Washington, Waukee, Waukesha, Wauwatosa, Wesley Chapel, West Allis, West Bend, West Bloomfield, West Des Moines, West Haven, Weston, West Reading, Westwood, Wilkes-Barre, Wilmington, Winston-Salem, Worcester, Ypsilanti
Age
18 years and over
People
2,000 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT05564390
Phase 1Taking people
Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies
Where
Bethesda
Age
18 years to 120 years
People
86
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06904066
Phase 1/2Not yet taking people in United States
Phase 1/2 FLAG-IDA, VEN and Asciminib in CML and Ph+ AML
Where
Houston
Age
18 years to 70 years
People
30
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT07604233
Phase 1Taking people
Phase 1 Open-label Study of AMX-883 Alone in Participants With AML and High-risk MDS and in Combination in Participants With AML
Where
Fairfax, New York
Age
18 years and over
People
54 worldwide
Run by
Amphista Therapeutics Ltd
See details and how to joinNCT07723703
Phase 1Taking people
Study of ORM-1153 in Acute Myeloid Leukemia (AML) With CD123 Expression
Where
Grand Rapids, Houston
Age
18 years and over
People
42
Run by
Orum Therapeutics USA, Inc.
See details and how to joinNCT07809906
Phase 1Not yet taking people in United States
A Study of CLEC2A CAR T for Pediatric and Adult Patients With Relapsed or Refractory AML
Where
Seattle
Age
Up to 70 years
People
20
Run by
Seattle Children's Hospital
See details and how to joinNCT07905027
Phase 1Not yet taking people in United States
Maintenance Treatment With Imetelstat in Patients With High-Risk Myeloid Neoplasms After Allo-SCT
Where
Madison
Age
18 years to 80 years
People
27
Run by
University of Wisconsin, Madison
See details and how to joinNCT07909733
Phase 1/2Taking people
Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT)
Where
Gainesville, Miami, St. Petersburg
Age
Up to 50 years
People
40
Run by
University of Florida
See details and how to joinNCT05322850
Phase 3Taking people
Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT
Where
Atlanta, Aurora, Baltimore, Birmingham, Boston, Cincinnati, Cleveland, Dallas, Detroit, Duarte, Gilbert, Grand Rapids, Iowa City, Los Angeles, New Orleans, Philadelphia, Portland, Rochester, Stony Brook, Tampa, Westwood
Age
18 years to 75 years
People
366 worldwide
Run by
Priothera SAS
See details and how to joinNCT05429632
No phaseTaking people
Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring
Where
Canton, Chapel Hill, Cleveland, Durham, Evanston, Massillon, New Haven
Age
18 years and over
People
25
Run by
Carevive Systems, Inc.
See details and how to joinNCT05974150
Phase 1Taking people
225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome
Where
Duarte
Age
18 years to 70 years
People
15
Run by
City of Hope Medical Center
See details and how to joinNCT06287944