Alcohol use disorder trials in United States

In United States 181 Also abroad 281

181 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Peer Support for Liver Transplant Recipients With History of ALD
Where
Baltimore
Age
18 years and over
People
95
Run by
Johns Hopkins University
See details and how to joinNCT07397598
Phase 1Taking people
PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder
Where
Bethesda
Age
18 years to 70 years
People
30
Run by
National Institute of Mental Health (NIMH)
See details and how to joinNCT06795581
Early phase 1Not yet taking people in United States
Examining the Role of Sensitivity to Uncertain Threat and Alcohol Response in Risk for Alcohol Use Disorder Following Sexual Assault in College Women
Where
Columbus
Age
21 years to 29 years
People
220
Run by
Ohio State University
See details and how to joinNCT07894289
Phase 2/3Taking people
Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder
Where
Philadelphia
Age
21 years to 65 years
People
60
Run by
University of Pennsylvania
See details and how to joinNCT06807918
No phaseTaking people
A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners
Where
Palo Alto
Age
18 years and over
People
744
Run by
Stanford University
See details and how to joinNCT05619185
Phase 1/2Taking people
Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms
Where
Bethesda
Age
18 years to 75 years
People
180
Run by
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
See details and how to joinNCT06484075
No phaseTaking people
AAT for Alcohol Use Disorder in Veterans
Where
San Diego
Age
18 years to 65 years
People
176
Run by
VA Office of Research and Development
See details and how to joinNCT05372029
Phase 2Taking people
Suvorexant for Treatment of AUD and PTSD
Where
Houston, Los Angeles
Age
21 years to 65 years
People
76
Run by
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
See details and how to joinNCT06679062
Phase 3Not yet taking people in United States
Recovery Management Checkup Scalability and Sustainability Hybrid Experiment
Where
Chicago
Age
18 years and over
People
600
Run by
Chestnut Health Systems
See details and how to joinNCT07873944
No phaseTaking people
Individual Variations of Taste and Smell Perception in Alcohol Use Disorder (AUD)
Where
Bethesda
Age
18 years to 65 years
People
475
Run by
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
See details and how to joinNCT05677321
Phase 1Taking people
Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)
Where
Bethesda
Age
21 years to 65 years
People
176
Run by
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
See details and how to joinNCT07559500
Phase 2Not yet taking people in United States
Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder
Where
Boston
Age
18 years to 65 years
People
36
Run by
Brigham and Women's Hospital
See details and how to joinNCT07296094
No phaseTaking people
Hepatic Lipid Metabolism-Alcohol Use Disorder
Where
Bethesda
Age
18 years to 100 years
People
25
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT07191561
No phaseTaking people
Combining a Smartphone App With Medications to Manage Heavy Drinking
Where
Battle Creek, Dallas, Decatur, Dublin, Fayetteville, Gainesville, Minneapolis, Nashville, Omaha, Phoenix, Richmond, Salt Lake City, San Antonio, Seattle, Washington D.C.
Age
18 years to 80 years
People
330
Run by
VA Office of Research and Development
See details and how to joinNCT06303778
Phase 3Taking people
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
Where
Baltimore, Birmingham, Boston, Chicago, Clinton, Dallas, Denver, DeSoto, Fairfax, Foxborough, Lakeland, Little Rock, Los Angeles, Maitland, Miami, Miami Gardens, Middleburg Heights, Orlando, Philadelphia, Richardson, Rockville, San Diego, San Francisco, Scottsdale, Seattle, Sioux Falls, Tampa, The Bronx
Age
18 years to 75 years
People
1,100 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07219966 · EU 2025-522313-38-00
Phase 4Taking people
Sex Differences in Trauma, Inflammation and Brain Function and the Implications for Treatment Efficacy in Alcohol Use Disorder
Where
Portland
Age
18 years to 60 years
People
100
Run by
Milky Kohno
See details and how to joinNCT06426303
Phase 2Taking people
Cannabis' Impact on Alcohol Consumption
Where
Providence
Age
21 years to 50 years
People
350
Run by
Brown University
See details and how to joinNCT05389930
Phase 2Not yet taking people in United States
Combination Therapy for Alcohol Use Disorder
Where
Havre de Grace
Age
21 years to 65 years
People
45
Run by
Johns Hopkins University
See details and how to joinNCT07249554
Phase 1/2Taking people
Intranasal Insulin for Treatment of Alcohol Use Disorder
Where
Providence
Age
21 years and over
People
40
Run by
Brown University
See details and how to joinNCT05988632
No phaseTaking people
DEVELOPMENT OF A NOVEL PEER RECOVERY SUPPORTER TRAINING PLATFORM
Where
Solon
Age
18 years and over
People
450
Run by
Thrive Digital Health, LLC
See details and how to joinNCT07044531
No phaseTaking people
tAN for Substance Use Disorder
Where
Houston
Age
18 years to 64 years
People
20
Run by
Spark Biomedical, Inc.
See details and how to joinNCT07281261
No phaseTaking people
Greek Connections Study
Where
Seattle
Age
18 years to 29 years
People
480
Run by
University of Washington
See details and how to joinNCT07839026
Phase 1Taking people
Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study
Where
West Haven
Age
21 years to 65 years
People
10
Run by
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
See details and how to joinNCT06335407
Phase 2Taking people
Orexin Receptor Antagonism for the Treatment of Alcohol Use Disorder and Stress-Related Drinking
Where
Columbus
Age
18 years to 65 years
People
250
Run by
Ohio State University
See details and how to joinNCT07214207
Phase 3Taking people
Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized Controlled Trial for Alcohol Use Disorder (CRAVE)
Where
Ann Arbor, Asheville, Cleveland, Dallas, Decatur, Durham, Hines, Houston, Long Beach, Madison, Minneapolis, Orlando, Palo Alto, Philadelphia, Portland, Salt Lake City, Tacoma, West Los Angeles
Age
18 years to 80 years
People
622
Run by
VA Office of Research and Development
See details and how to joinNCT07218354