Alcohol use disorder trials in United States

In United States 181 Also abroad 281

181 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
A First in Human Study of CMND-100 in Healthy and Alcohol Use Disorder (AUD) Subjects
Where
Baltimore, New Haven
Age
18 years to 60 years
People
84 worldwide
Run by
Clearmind Medicine Inc.
See details and how to joinNCT05913752
Phase 2/3Enrolling by invitation
Relationship Between Brain and Heart Glucose Metabolism in Alcohol Use Disorder
Where
Philadelphia
Age
21 years to 65 years
People
20
Run by
University of Pennsylvania
See details and how to joinNCT05015881
No phaseTaking people
Virtual Reality (VR) NATURE - Alcohol Use Disorder (AUD)
Where
Ann Arbor
Age
18 years and over
People
50
Run by
University of Michigan
See details and how to joinNCT07413458
Phase 2Taking people
Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide
Where
Decatur
Age
18 years to 99 years
People
30
Run by
Yale University
See details and how to joinNCT07040592
No phaseTaking people
Non-invasive Vagal Nerve Stimulation as Novel Treatment to Improve Functional Outcomes in Veterans With Alcohol Use Disorder
Where
San Diego
Age
21 years to 65 years
People
80
Run by
VA Office of Research and Development
See details and how to joinNCT06399653
No phaseNot yet taking people in United States
A Study of the Effect of a Nurse Navigator Program on High Risk Patients
Where
Jacksonville
Age
18 years and over
People
300
Run by
Mayo Clinic
See details and how to joinNCT05592847
Phase 2Not yet taking people in United States
Pilot Study: Effects of Nimodipine on Alcohol Drinking
Where
New Haven
Age
21 years to 50 years
People
5
Run by
Yale University
See details and how to joinNCT06900998
Phase 2Taking people
Probenecid Administration for Alcohol Craving and Consumption
Where
Providence
Age
18 years and over
People
120
Run by
Brown University
See details and how to joinNCT07118618
No phaseNot yet taking people in United States
Social Identity Mapping for Adolescent Recovery
Where
Boston
Age
12 years to 19 years
People
60
Run by
Massachusetts General Hospital
See details and how to joinNCT07474207
No phaseTaking people
Integrated Treatment for Enhancing Growth in Recovery During Adolescence
Where
Boston, Farmington
Age
14 years to 21 years
People
294
Run by
Massachusetts General Hospital
See details and how to joinNCT06395467
Phase 2Taking people
Mechanistic Evaluation of Guanfacine on Drinking Behavior in Women and Men With Alcohol Use Disorders
Where
New Haven
Age
21 years to 70 years
People
160
Run by
Yale University
See details and how to joinNCT03764098
No phaseTaking people
Mechanisms of Risky Alcohol Use in Young Adults: Linking Sleep to Reward- and Stress-Related Brain Function
Where
Eugene
Age
18 years to 24 years
People
90
Run by
University of Oregon
See details and how to joinNCT05684094
No phaseTaking people
Alcohol Research in HIV: Relapse Prevention
Where
Baltimore
Age
18 years and over
People
150
Run by
Johns Hopkins University
See details and how to joinNCT05163301
No phaseEnrolling by invitation
Peer Delivered, Emotion Regulation-Focused Mental Health Prevention Training for Fire Fighter Trainees
Where
Waco
Age
21 years and over
People
480
Run by
Baylor Research Institute
See details and how to joinNCT06290778
Early phase 1Taking people
Anxiety During Abstinence in AUD
Where
New York
Age
21 years to 55 years
People
60
Run by
Columbia University
See details and how to joinNCT06793488
Early phase 1Not yet taking people in United States
PTSD and Alcohol Couples Treatment for Veterans
Where
Charleston
Age
18 years and over
People
80
Run by
VA Office of Research and Development
See details and how to joinNCT07388654
Phase 2/3Taking people
Ketone Ester Intervention in Alcohol Use Disorder
Where
Philadelphia
Age
21 years to 65 years
People
20
Run by
University of Pennsylvania
See details and how to joinNCT04616781
No phaseTaking people
Brief Family Involved Treatment Telehealth
Where
Charleston
Age
21 years and over
People
400
Run by
Medical University of South Carolina
See details and how to joinNCT05674409
No phaseTaking people
Image-guided, Robot Navigated Transcranial Magnetic Stimulation (IR-TMS) for Alcohol Use Disorder (AUD)
Where
San Antonio
Age
18 years to 65 years
People
150
Run by
The University of Texas Health Science Center at San Antonio
See details and how to joinNCT06648642
No phaseTaking people
Enhancing Alcohol Treatment Engagement in Associated Liver Disease (ALD) Patients
Where
Detroit
Age
18 years and over
People
268
Run by
Henry Ford Health System
See details and how to joinNCT06269510
Phase 2Taking people
Pregnenolone for the Treatment of Alcohol Use Disorder
Where
New Haven
Age
18 years to 70 years
People
150
Run by
Yale University
See details and how to joinNCT05781009
No phaseTaking people
A Randomized Controlled Trial of Digital CBT to Treat Addiction: Digital RITch®CBT vs. Standard CBT
Where
Rochester
Age
18 years to 65 years
People
40
Run by
University of Rochester
See details and how to joinNCT05943171
No phaseTaking people
Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons
Where
Bismarck, Little Rock, Osceola, Texarkana, West Memphis
Age
18 years and over
People
640
Run by
University of Arkansas
See details and how to joinNCT06923423
Phase 4Taking people
Naltrexone in AUD Reward Drinkers
Where
Philadelphia
Age
18 years to 65 years
People
60
Run by
University of Pennsylvania
See details and how to joinNCT05028062
No phaseTaking people
Acute Alcohol Response In Bipolar Disorder: a Longitudinal Alcohol Administration/fMRI Study
Where
Austin
Age
21 years to 26 years
People
100
Run by
University of Texas at Austin
See details and how to joinNCT05838274