Alzheimer disease: open trials in Canada

57 open trials have a site in Canada. Registry data; only the trial team decides who can take part.

NCT04516057
Nabilone for Agitation Blinded Intervention Trial
Trial Treatment · Phase 3 · Sunnybrook Health Sciences Centre
University Of Calgary, Calgary · Geras Centre for Aging Research, Hamilton Health Sciences, Hamilton · London Health Sciences Centre, London · The University of Ottawa Institute of Mental Health Research at The Royal, Ottawa · Centre for Addiction and Mental Health, Toronto · St. Michael's Hospital, Toronto · Sunnybrook Health Sciences Centre, Toronto · Ontario Shores Centre for Mental Health Sciences, Whitby
Registry updated 2026-11-06
NCT07011732
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Hamilton · London · London Health Sciences Centre-Victoria Campus, London · Montreal · Sunnybrook Research Institute, Toronto · Centre for Addiction & Mental Health, Toronto · Ontario Shores Centre for Mental Health Sciences, Whitby
Registry updated 2026-11-06
NCT07284472
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
Trial Treatment · Phase 2/3 · Exciva GmbH
Baycrest Centre for Geriatric Care, North York · Sunnybrook Health Sciences Centre, North York · Kawartha Centre, Peterborough · Ontario Shores Centre for Mental Health Sciences, Whitby
Registry updated 2026-11-06
NCT07688213
A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease
Trial Treatment · Phase 2 · Sanofi
Montreal · Ottawa · Toronto
Registry updated 2026-11-06
NCT07717411
A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease
Trial Treatment · Phase 3 · Hoffmann-La Roche
Kelowna Health and Memory Centre Ltd., Kelowna · Genge Partners Inc., Montreal · Kawartha Regional Memory Clinic, Peterborough · Alpha Recherche Clinique, Québec · Toronto Memory Program, Toronto · Centricity Research Toronto, Toronto
Registry updated 2026-11-06
NCT07762092
A Post Authorization Registry Study of Participants Treated With LEQEMBI
Research · Eisai Limited
University of Calgary - Hotchkiss Brain Institute, Calgary · University of Alberta, Geriatric Division, Edmonton · Clinique Neuro-Outaouais, Gatineau · MOCA, Greenfield Park · Kingston HHC (Queen University), Kingston · Parkwood Hospital - London, London · Trillium Hospital, Mississauga · McGill University, Douglas Mental Health, Montreal · IUGM, Montreal · Bruyère Institute, Ottawa · Kawartha Center, Peterborough · CHU de Québec-Université Laval Research Center, Québec · Toronto Memory Program, Toronto · Sunnybrook Hospital, Toronto · Toronto Western Hospital, Toronto · University of British Columbia - CARD, Vancouver · UBC Victoria - Neil and Susan Manning Cognitive Health Initiative, Victoria
Registry updated 2026-11-05
NCT07912736
BioMIND Biospecimen Repository
Research · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Parkwood Institute, London
Registry updated 2026-11-03
NCT06976216
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
Trial Treatment · Phase 3 · Bristol-Myers Squibb
MoCA Research and Innovation Inc., Greenfield Park · Centricity Research Halifax Multispecialty, Halifax · OCT Research ULC, Kelowna · Ottawa Memory Clinic, Ottawa · Alpha Recherche Clinique, Québec · Richmond Clinical Trials, Richmond · Toronto Memory Program, Toronto · Diex Recherche Victoriaville, Victoriaville
Registry updated 2026-10-27
NCT07893678
Virtual Reality to Advance Dementia Care and Quality of Life
Trial Treatment · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Parkwood Institute Finch Family Mental Health Care Building, London · LHSC Victoria Hospital, London
Registry updated 2026-10-26
NCT05231785
A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD
Trial Treatment · Phase 1 · Alnylam Pharmaceuticals
Montreal · Toronto
Registry updated 2026-10-20
NCT07033494
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Clinique Mémoire de Montreal (Site 2000), Montreal · Ottawa Memory Clinic (Site 2001), Ottawa · Toronto Western Hospital (Site 2004), Toronto · Sunnybrook Research Institute (Site 2003), Toronto
Registry updated 2026-10-20
NCT07883746
Remote Digital Assessments for Cognitive Disorders
Research · Centre for Addiction and Mental Health
Centre for Addiction and Mental Health (CAMH), Toronto
Registry updated 2026-10-20
NCT07177352
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
Trial Treatment · Phase 3 · Hoffmann-La Roche
True North Clinical Research-Halifax, Halifax · Okanagan Clinical Trials, Kelowna · Kelowna Health and Memory Centre Ltd., Kelowna · Parkwood Institute, Mental Health Care Building, London · Genge Partners Inc., Montreal · Clinique Mémoire de Montréal, Montreal · Bruyère Health Research Institute, Ottawa · The Ottawa Memory Clinic, Ottawa · Kawartha Regional Memory Clinic, Peterborough · Alpha Recherche Clinique, Québec · Richmond Clinical Trials, Richmond · Baycrest Health Sciences, Toronto · Toronto Memory Program, Toronto · Centricity East York, Toronto · Toronto Western Hospital, Toronto · St. Michael's Hospital, Toronto · Sunnybrook Health Sciences Centre, Toronto
Registry updated 2026-10-19
NCT05980949
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
Trial Treatment · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Local Institution - 1-12IRCCNP, Calgary · Hamilton · Local Institution - 1-12IYJCH7, Montreal · Verdun · Whitby
Registry updated 2026-10-16
NCT06126224
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)
Trial Treatment · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Calgary · Hamilton · Montreal · Toronto · Verdun · Whitby
Registry updated 2026-10-16
NCT06937229
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Hamilton · London · Toronto · Toronto · Ontario Shores Centre for Mental Health Sciences, Whitby
Registry updated 2026-10-16
NCT05176704
Development of Eye-movement Based Biomarkers in Alzheimer's Disease
Research · McGill University
The Douglas Research Centre, Montreal · Cornelius, a Residence of Groupe Maurice, Montreal · Elogia, a Residence of Groupe Maurice, Montreal · ORA, A residence of Groupe Maurice, Montreal · The Montreal Neurological Institute, Ville-Marie
Registry updated 2026-10-14
NCT07214727
A Study to Evaluate ALN-5288 in Patients With Alzheimer's Disease
Trial Treatment · Phase 1 · Alnylam Pharmaceuticals
Montreal · Ottawa · Toronto
Registry updated 2026-10-08
NCT00869817
Dominantly Inherited Alzheimer Network (DIAN)
Research · Washington University School of Medicine
McGill University Research Centre for Studies in Aging, Verdun
Registry updated 2026-10-05
NCT06189963
Clinical Study of SNK01 in Participants With Moderate Alzheimer's Disease
Trial Treatment · Phase 1/2 · NKGen Biotech, Inc.
Ottawa Memory Clinic, Ottawa
Registry updated 2026-10-02
NCT06887192
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
Trial Treatment · Phase 2 · MapLight Therapeutics
Brampton · Lévis · London · Toronto
Registry updated 2026-09-30
NCT05617014
Alzheimer's Disease Neuroimaging Initiative 4
Research · University of Southern California
Parkwood Institute, London · Sunnybrook Health Sciences Centre, Toronto · UBC Hospital Clinic for Alzheimer Disease and Related Disorders (CARD), Vancouver
Registry updated 2026-09-29
NCT07221344
Study of ARO-MAPT-SC in Healthy Participants and Participants With Early Alzheimer's Disease
Trial Treatment · Phase 1/2 · Arrowhead Pharmaceuticals
East York · Montreal · Toronto
Registry updated 2026-09-18
NCT06767124
Veech Ketone Ester to Support Brain Energy in Mild Cognitive Impairment and Early Alzheimer's Disease
Trial Treatment · University of Pennsylvania
Lawson Research Institute, London
Registry updated 2026-08-26
NCT04335994
ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing
Trial Treatment · Sunnybrook Health Sciences Centre
Sunnybrook Health Sciences Centre, Toronto
Registry updated 2026-08-20

All Alzheimer disease trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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