Alzheimer disease: open trials in Germany

28 open trials have a site in Germany. Registry data; only the trial team decides who can take part.

NCT07284472
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
Trial Treatment · Phase 2/3 · Exciva GmbH
Praxis Dr. med. Kirsten Hahn, Berlin · Studienzentrum Dr. Bischof GmbH, Boeblingen · Pharmakologisches Studienzentrum Chemnitz GmbH, Chemnitz · Curiositas ad sanum Studien und Beratungs GmbH, Ebersberg · Zentrum für Psychiatrie Emmendingen, Emmendingen · Klinikum der Technischen Universitaet Muenchen (TUM Klinikum), Munich
Registry updated 2026-11-06
NCT07688213
A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease
Trial Treatment · Phase 2 · Sanofi
Kallmann Neurologie Neurologische Praxis, Bamberg · Charite Universitaetsmedizin Berlin KöR, Berlin · Gesundheit Nord gGmbH Klinikverbund Bremen, Bremen · Universitaetsklinikum Koeln AöR, Cologne · Medizinische Hochschule Hannover, Hanover
Registry updated 2026-11-06
NCT07781657
Study to Test Effects and Safety of RO7568282 in Early Symptomatic Alzheimer's Disease
Trial Treatment · Phase 2 · Hoffmann-La Roche
Universitaetsklinikum Aachen AöR, Aachen · Charite Universitaetsmedizin Berlin KöR, Berlin · Medical Center- University of Freiburg, Freiburg im Breisgau · Universitaetsklinikum Jena KöR, Jena · Universitaet Muenster, Muenster · Klinikum der Technischen Universitaet Muenchen (TUM Klinikum), Munich
Registry updated 2026-11-06
NCT07011745
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Düsseldorf · Halle · Westerstede
Registry updated 2026-11-03
NCT06585787
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Trial Treatment · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Neuro Centrum Science GmbH, Erbach · Goethe University Frankfurt, Frankfurt Am Main
Registry updated 2026-10-27
NCT06976216
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Universitaetsklinikum Aachen AöR, Aachen · Charite Universitaetsmedizin Berlin KöR, Berlin · Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, Mainz · Zentralinstitut Fuer Seelische Gesundheit, Mannheim · Universitaet Muenster, Muenster · Klinikum der Technischen Universitaet Muenchen (TUM Klinikum), Munich
Registry updated 2026-10-27
NCT05980949
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
Trial Treatment · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Studienzentrum Dr. Bischof GmbH, Boeblingen · Neuro Centrum Science GmbH, Erbach · Goethe University Frankfurt, Frankfurt Am Main · Universitaet Des Saarlandes, Homburg
Registry updated 2026-10-16
NCT06937229
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Düsseldorf · Halle · Westerstede
Registry updated 2026-10-16
2024-517187-36-01
A Study of Treatments for the Prevention of Disease Progression in Individuals at Risk for or With Early Onset Alzheimer’s Disease Caused by a Genetic Mutation
Trial Treatment · Phase 2/3 · Washington University School Of Medicine
Deutsches Zentrum Fuer Neurodegenerative Erkrankungen e.V., Munich · Deutsches Zentrum Fuer Neurodegenerative Erkrankungen e.V., Tuebingen
Registry updated 2026-10-13
NCT06313944
German Registry of Alzheimer's Disease Treated With Transcranial Pulse Stimulation
Research · Heinrich-Heine University, Duesseldorf
Universitätsklinikum Bonn - Klinik für Parkinson, Schlaf- und Bewegungsstörungen, Bonn · Hospital zum Heiligen Geist GmbH & Co KG Klinik für Neurologie und Neurorehabilitation, Kempen · Neurologische Praxis Prof. Wojtecki, Neuss · Evangelische Krankenhausstiftung Oldenburg - Universitätsklinik für Neurologie, Oldenburg · Ernst von Bergmann Klinikum - Klinik für Neurologie und Klinische Neuropsychologie, Potsdam · Praxis Dr. Schwarz, Ulm
Registry updated 2026-10-13
NCT07636811
A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)
Trial Treatment · Phase 2 · Alnylam Pharmaceuticals
This trial only enrols participants with Down syndrome
Gesundheit Nord gGmbH Klinikverbund Bremen, Bremen · LMU Klinikum Muenchen AöR, Munich
Registry updated 2026-10-13
NCT06976203
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Zentrum fuer klinische Forschung Dr. I. Schoell GmbH, Bad Homburg · Pharmakologisches Studienzentrum Chemnitz GmbH, Chemnitz · University Hospital Cologne AöR, Cologne · Universitaetsmedizin Goettingen, Goettingen · LMU Klinikum Muenchen AöR, Munich · Universitaetsklinikum Ulm AoR, Ulm
Registry updated 2026-10-08
NCT00869817
Dominantly Inherited Alzheimer Network (DIAN)
Research · Washington University School of Medicine
German Center for Neurodegenerative Diseases (DZNE) Munich, and University Hospital Ludwig-Maximilians-Universitat (LMU) Munich, Munich · German Center for Neurodegenerative Diseases (DZNE) Tübingen and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen
Registry updated 2026-10-05
NCT07383311
Autophagy-Enhancers to Reduce Sleep Disturbances
Trial Treatment · University Medicine Greifswald
Department of Neurology, University Medicine Greifswald, Greifswald
Registry updated 2026-10-02
NCT05511363
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)
Trial Treatment · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Bayreuth · Böblingen · Homburg
Registry updated 2026-08-17
NCT05552157
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Trial Treatment · Phase 2/3 · Washington University School of Medicine
LMU-Campus Grosshadern, Munich · Universitaetsklinikum Tubingen, Tübingen
Registry updated 2026-07-27
NCT06647498
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Trial Treatment · Phase 2/3 · Washington University School of Medicine
LMU-Campus Grosshadern, Munich · Universitaetsklinikum Tubingen, Tübingen
Registry updated 2026-07-27
NCT07721701
Digital Dementia Registry Bavaria (digiDEM Bayern): a Multicentre, Prospective, Longitudinal Register Study Including People With Mild Cognitive Impairment and Dementia as Well as Their Family Caregivers
Research · University of Erlangen-Nürnberg Medical School
Klinikum Aschaffenburg-Alzenau, Aschaffenburg · Schön Klinik Bad Aibling, Bad Aibling · RHÖN-KLINIKUM Campus Bad Neustadt, Bad Neustadt an der Saale · Klinikum Bayreuth, Bayreuth · Klinikum Coburg, Regiomed Zentrum für Altersmedizin, Coburg · Kliniken Am Goldenen Steig, Freyung · Schön Klinik München Schwabing, München · Marion von Tessin Memory-Zentrum, München · Klinikum Neumarkt, Neumarkt · Klinikum Nürnberg, Nuremberg · Klinik und Poliklinik für Psychiatrie Regensburg, Regensburg · Böhm-Peters - Praxis für Psychiatrie, Psychotherapie und Neurologie, Rosenheim
Registry updated 2026-07-23
2023-503705-10-00
Patient- and care-related benefits of amyloid PET imaging (ENABLE)
Trial Treatment · Phase 4 · Deutsches Zentrum Fuer Neurodegenerative Erkrankungen e.V.
Charite Universitaetsmedizin Berlin KöR, Berlin · Deutsches Zentrum Fuer Neurodegenerative Erkrankungen e.V., Bonn · University Hospital Cologne AöR, Cologne · Technische Universität Dresden, Dresden · University Of Erlangen Nuremberg, Erlangen · Universitaetsklinikum Essen (AoR), Essen · Medical Center- University of Freiburg, Freiburg im Breisgau · Universitaetsmedizin Goettingen, Goettingen · Universitaetsmedizin Greifswald KöR, Greifswald · University Medical Center Hamburg-Eppendorf, Hamburg · Universitaet Leipzig, Leipzig · Universitaetsklinikum Magdeburg AöR, Magdeburg · Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, Mainz · Central Institute of Mental Health, Mannheim · Universitaetsklinikum Mannheim GmbH, Mannheim · Universitaetsklinikum Giessen und Marburg GmbH, Marburg · Philipps University Marburg, Marburg · Klinikum der Universitaet Muenchen AöR, Munich · Klinikum rechts der Isar der TU Muenchen AöR, Munich · Rostock University Medical Center, Rostock · Universitaetsklinikum Tuebingen AöR, Tuebingen · Universitaetsklinikum Ulm AoR, Ulm
Registry updated 2026-07-17
NCT07564700
A Study Testing Whether Low-Dose Radiation Could Help the Immune System and Possibly Improve Early-Onset Alzheimer's Disease.
Trial Treatment · Heinrich-Heine University, Duesseldorf
Klinik für Strahlentherapie und Radioonkologie, Düsseldorf
Registry updated 2026-05-04
NCT06995573
A Study to Assess Safety and Tolerability and to Explore Efficacy of NSC001 in Mild to Moderate Alzheimer's Disease
Trial Treatment · Phase 1/2 · NSC-Therapeutics
Klinikum Altenburger Land GmbH, Altenburg · Zentrum fuer klinische Forschung Dr. I. Schoell GmbH, Bad Homburg · Katholisches Klinikum Bochum gGmbH, Bochum · Universitaetsmedizin Goettingen, Goettingen · Uniklinik Köln, Köln · Dynamikos GmbH Institut fuer Studien zur Psychischen Gesundheit, Mannheim · Sanos Clinic GmbH, Ratingen
Registry updated 2026-04-17
NCT07466394
COGSCREEN II: Early Detection of Cognitive Impairment
Trial Treatment · Robert Perneczky
Klinik für Psychiatrie und Psychotherapie am LMU Klinikum, München
Registry updated 2026-03-12
NCT07433010
German Dementia Registry
Research · RWTH Aachen University
RWTH Aachen University Hospital, Aachen · Charité Campus Benjamin Franklin, Berlin · Charité Universitätsmedizin Berlin, Berlin · Klinikum Bremen-Ost, Bremen · University Hospital Cologne, Cologne · Universitätsklinikum Erlangen, Erlangen · University Hospital Essen, Essen · Klinikum Frankfurt (Oder), Frankfurt (Oder) · University Medical Center Göttingen, Göttingen · Greifswald University Medicine, Greifswald · Asklepios Klinik Nord, Hamburg · Medical Center Hamburg-Eppendorf, Hamburg · Heidelberg University Hospital, Heidelberg · Saarland University Medical Center, Homburg · University Hospital Jena, Jena · University Hospital Schleswig-Holstein, Kiel · Pfalzklinikum Klingenmünster, Klingenmünster · University of Leipzig Medical Center, Leipzig · Madical Faculty University Hospital Magdeburg, Magdeburg · University Medical Center Mainz, Mainz · ZI Mannheim, Mannheim · Immanuel Klinik Rüdersdorf, Rüdersdorf · University Hospital Tübingen, Tübingen · Ulm University Hospital, Ulm
Registry updated 2026-02-25
NCT07402356
VR Pupillometry in Cognitive Impairment
Research · Max-Planck-Institute of Psychiatry
Max Planck Institute of Psychiatry, München
Registry updated 2026-02-17
2022-501137-23-00
A Phase 2 Trial Evaluating the Effects of Thiethylperazine as diagnostic tool and therapeutic agent in Patients Diagnosed with an Early Stage of Alzheimer's disease
Trial Treatment · Phase 2 · Immungenetics AG
University Duisburg-Essen, Essen · Universitaetsklinikum Essen (AoR), Essen · Universitaetsmedizin Goettingen, Göttingen · Medizinische Hochschule Hannover, Hanover · Central Institute of Mental Health, Mannheim · Ludwig Maximilian University Of Munich, Munich · Rostock University Medical Center, Rostock · University Hospital Of Ulm AöR, Ulm
Registry updated 2025-12-08

All Alzheimer disease trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

Report an error