Alzheimer disease: open trials in United States

359 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT06930560
HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms
Trial Treatment · Johns Hopkins University
Johns Hopkins Memory and Alzheimer's Treatment Center, Baltimore
Registry updated 2026-11-06
NCT07011732
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Advanced Research Center (ARC) - Anaheim, Anaheim · The Memory Clinic, Bennington · NeuroBehavioral Medicine Group, Bloomfield Hills · Colorado Springs · Columbia · Advanced Neurology Epilepsy and Sleep Center, El Paso · Foxborough · Fresno · CBH Health, Gaithersburg · Inwood · La Jolla · Redbird Research, Las Vegas · Maitland · Maitland · Marrero · Flourish Research, Merritt Island · Miami · Miami · Miami · Middletown · Boston Center for Memory, Newton · New Windsor · Ocala · Combined Research Orlando (CRO), Orlando · The Neurology Group, Pomona · Progressive Medical Research, Port Orange · Global Medical Institutes LLC; Princeton Medical Institute, Princeton · Wasatch Clinical Research, LLC, Salt Lake City · Imaging Endpoints, Scottsdale · Seattle · Mayflower Clinical Research, South Dartmouth · Spokane · Voltaire Springfield, Springfield · St Louis · Torrance · Oakland Medical Research, Troy · Central States Research, Tulsa · Hope Research Network - Miami, Virginia Gardens · Sunwise Clinical Research, Walnut Creek · Five Towns Neurology PC -Woodmere - 923 Broadway, Woodmere · Woodmere
Registry updated 2026-11-06
NCT07169630
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
Trial Treatment · Phase 1 · National Institute of Mental Health (NIMH)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-11-06
NCT07284472
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
Trial Treatment · Phase 2/3 · Exciva GmbH
The Memory Clinic, Bennington · Integrative Clinical Trials, Brooklyn · Precise Research Centers, Flowood · Insight Clinical Trials, Independence · Josephson Wallack Munshower Neurology, PC, Indianapolis · Esperanza Clinical, Murrieta · Manhattan Behavioral Medicine, New York · Oregon Health Science University, Portland
Registry updated 2026-11-06
NCT07651319
Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's Disease
Trial Treatment · Phase 1/2 · The Methodist Hospital Research Institute
Houston Methodist Research Institute, Houston
Registry updated 2026-11-06
NCT07688213
A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease
Trial Treatment · Phase 2 · Sanofi
Kerwin Medical Center- Site Number : 8400006, Dallas · Rhode Island Mood & Memory Research Institute- Site Number : 8400015, East Providence · Healthy Brain Clinic- Site Number : 8400011, Long Beach · Naples · Boston Center for Memory - Newton- Site Number : 8400007, Newton · Oakland · K2 Medical Research - Orlando - South Orlando Avenue- Site Number : 8400008, Orlando · Flourish Research - Keystone Clinical Studies- Site Number : 8400003, Plymouth Meeting · Summit Research Network - Portland - Northwest Vaughn Street- Site Number : 8400002, Portland · The Cognitive and Research Center of New Jersey - Springfield- Site Number : 8400005, Springfield · Alzheimer's Research and Treatment Center - Stuart, FL- Site Number : 8400014, Stuart · Axiom Brain Health- Site Number : 8400019, Tampa · Charter Research - Lady Lake- Site Number : 8400004, The Villages · Alzheimer's Research and Treatment Center - Wellington- Site Number : 8400012, Wellington
Registry updated 2026-11-06
NCT07717411
A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease
Trial Treatment · Phase 3 · Hoffmann-La Roche
Sana Research, LLC, Arlington · Adams Clinical Boston, Boston · Great Lakes Clinical Trials Chicago d/b/a Flourish Research Andersonville, Chicago · Alzheimer's Research and Treatment Center - Columbus, Columbus · Hawaii Pacific Neuroscience, Honolulu · Irvine Center for Clinical Research, Irvine · Basil Clinical, Laurelton · Healthy Brain Clinic, Long Beach · Inglewood Clinicals, Los Angeles · K2 Medical Research, LLC, Maitland · Boston Center for Memory, Newton · Oakland Clinical, Oakland · Renstar Medical Research, Ocala · Charter Research - Winter Park/Orlando, Orlando · Conquest Research - Lake Nona, Orlando · National Clinical Research Inc.-Richmond, Richmond · Riverside Clinical, Riverside · Syrentis Clinical Research, Santa Ana · Cenexel California Neuroscience Research, LLC, Sherman Oaks · Alzheimer's Research and Treatment Center, Stuart · Charter Research - Lady Lake/The Villages, The Villages · Adams Clinical Watertown, Watertown · Alzheimer's Research and Treatment Center, Wellington · Conquest Research, LLC, Winter Park
Registry updated 2026-11-06
NCT07721467
Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin
Trial Treatment · Phase 2 · National Institute on Aging (NIA)
National Institute of Aging, Clinical Research Unit, Baltimore
Registry updated 2026-11-06
NCT07781657
Study to Test Effects and Safety of RO7568282 in Early Symptomatic Alzheimer's Disease
Trial Treatment · Phase 2 · Hoffmann-La Roche
Basil Clinical, Laurelton · Alzheimer's Research and Treatment Center, Stuart · Alzheimer's Research and Treatment Center, Wellington · Conquest Research, LLC, Winter Park
Registry updated 2026-11-06
NCT06159673
ACP-204 in Adults With Alzheimer's Disease Psychosis
Trial Treatment · Phase 2/3 · ACADIA Pharmaceuticals Inc.
Abington Neurological Associates, Abington · Dent Neurologic Institute, Amherst · Advanced Research Center, Inc., Anaheim · Agile Clinical Research Trials, LLC, Atlanta · Humanity Clinical Research, Corp, Aventura · Insight Clinical Trials LLC, Beachwood · Valley Medical Research, Centerville · Chandler Clinical Trials, Chandler · ATP Clinical Research, Costa Mesa · Horizon Clinical Research Group, Cypress · NDx Clinical Research Inc., Dayton · Arrow Clinical Trials, Daytona Beach · First Excellent Research Group, Doral · Revive Research Institute, Inc., Elgin · Neuro-Pain Medical Center, Fresno · CBH Health LLC, dba CenExcel Gaithersburg, Gaithersburg · National Institute Of Clinical Research, Garden Grove · New Life Medical Research Center, Inc, Hialeah · Reliable Clinical Research LLC, Hialeah · Clinical Trial Network LLC, Houston · University of Texas Health Science Center, Houston · Steven South Goldstein MD and Associates, Houston · Kaleidoscope Clinical Research, Houston · Prolato Clinical Research Center-Patton, Houston · Alivation Research, LLC, Lincoln · Advanced Memory Research Institute of New Jersey, Marlton · Premier Clinical Research Institute Inc, Miami · ABBA Medical Group LLC, Miami · Homestead Associates in Research Inc., Miami · MediClear Medical & Research Center, Inc., Miami · Visionary Investigators Network, Miami · Advanced Clinical Research Network, Corp, Miami · Verus Clinical Research, Miami · Central Miami Medical Institute, Miami · Future Care Solution LLC, Miami · Quantum Clinical Trials, Miami Beach · New Med Research, Miami Gardens · Floridian Neuroscience Institutue, Miami Lakes · Combined Research Orlando Phase I-IV, Orlando · Havana Research Institute LLC, Pasadena · World Research Link, Pasadena · Quantum Clinical Research, Inc., Pasadena · Finger Lakes Clinical Research, Rochester · Khan Revive Research Institute, Rochester Hills · Clinical Endpoint LLC, Scottsdale · Grace Research, LLC, Shreveport · R & H Clinical Research Inc., Stafford · Tekton Research LLC, St Louis · SUNY Upstate Medical University, Syracuse · Psych Me Medical Research Inc, Tampa · Regional Neurological Associates, The Bronx · Tranquil Clinical Research, Webster · Neuroscience Research Institute, West Palm Beach
Registry updated 2026-11-05
NCT07787169
A Master Protocol Studying Multiple Amyloid-Targeting Therapies in Healthy Participants and Participants With Alzheimer's Disease
Trial Treatment · Phase 1 · Eli Lilly and Company
CenExel ACT, Anaheim · Fortrea Clinical Research Unit, Daytona Beach · Accel Research Sites - NeuroStudies Clinical Research Unit, Decatur · QUEST Research Institute, Farmington Hills · Irvine Clinical Research, Irvine · K2 MEDICAL Research THE VILLAGES, Lady Lake · Collaborative Neuroscience Network - CNS, Los Alamitos · K2 Medical Research, Maitland · Charter Research, Orlando · Progressive Medical Research, Port Orange · Alzheimer's Research and Treatment Center, Stuart · K2 Medical Research - Tampa, Tampa · Charter Research, The Villages
Registry updated 2026-11-05
NCT07873463
Flutemetamol F 18 Injection Formulation Comparison
Trial Treatment · Phase 2 · GE Healthcare
Visionary Investigator Network, Aventura · Center for Advanced Research & Education LLC dba Flourish Research Gainesville, Gainesville · Meritt Island Research, LLC dba. Flourish Research, Merritt Island · Visionary Investigator Network, Miami · Clinical Site Partners, LLC dba Flourish Research, Winter Park
Registry updated 2026-11-05
NCT06194799
ACP-204 in Adults With Alzheimer's Disease Psychosis Open Label Extension Study
Trial Treatment · Phase 3 · ACADIA Pharmaceuticals Inc.
Abington Neurological Associates, Abington · Humanity Clinical Research, Corp, Aventura · ATP Clinical Research, Costa Mesa · Horizon Clinical Research Group, Cypress · First Excellent Research, Doral · Neuro-Pain Medical Center, Fresno · National Institute Of Clinical Research, Garden Grove · New Life Medical Research Center, Hialeah · Reliable Clinical Research LLC, Hialeah · Kaleidoscope Clinical Research, Houston · Uni Texas Health Science Center, Houston · Clinical Trial Network LLC, Houston · MediClear Medical & Research Center, Inc., Miami · Future Care Solution LLC, Miami · Advanced Clinical Research, Miami · Homestead Associates in Research Inc., Miami · Verus Clinical Research, Miami · Premier Clinical Research Institute Inc, Miami · ABBA Medical Research LLC, Miami · Quantum Clinical Trials, Miami · New Med Research, Miami Gardens · Floridian Neuroscience Institute, Miami Lakes · Clinical Endpoints, LLC, Scottsdale
Registry updated 2026-11-04
NCT07589595
A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
Trial Treatment · Phase 2 · Eli Lilly and Company
JEM Research Institute, Atlantis · VIN - Aventura, Aventura · Gadolin Research, Beaumont · Citizens Memorial Hospital District, Bolivar · Profound Research LLC, Carlsbad · TrialSphere Corp, Chandler · Massachusetts General Hospital - Charlestown, Charlestown · Kerwin Medical Center, Dallas · Brain Matters Research, Delray Beach · CenExel Rocky Mountain Clinical Research, Englewood · Re:Cognition Health, Fairfax · The University of Kansas - Clinical Research Center, Fairway · QUEST Research Institute, Farmington Hills · Neuropsychiatric Research Center of Southwest Florida, Fort Myers · Neurology Center of New England, Foxborough · K2 Medical Research - Foxborough, Foxborough · Norman Fixel Institute for Neurological Diseases (FIND), Gainesville · Struthers Parkinson's Center, Golden Valley · Houston Methodist Hospital, Houston · The University of Texas Health Science Center at Houston, Houston · Indiana University Health Neuroscience Center, Indianapolis · Irvine Clinical Research, Irvine · Mayo Clinic in Florida, Jacksonville · EvergreenHealth, Kirkland · UCSD - Altman Clinical and Translational Research Institute (ACTRI), La Jolla · K2 Medical Research ORLANDO, Maitland · BRP-Kendal Lakes, Miami · Renstar Medical Research, Ocala · Charter Research - Orlando, Orlando · Stanford Neuroscience Health Center, Palo Alto · Pennsylvania Hospital, Philadelphia · Headlands Eastern MA LLC, Plymouth · Oregon Health and Science University, Portland · Summit Headlands, Portland · Mayo Clinic in Rochester, Minnesota, Rochester · Central Texas Neurology Consultants, Round Rock · The University of Texas Health Science Center, San Antonio · HonorHealth Research Institute, Scottsdale · Ki Health Partners, LLc, dba New England Institute for Clinical Research, Stamford · Axiom Brain Health LLC, Tampa · Palm Beach Neurology, West Palm Beach · Conquest Research, Winter Park
Registry updated 2026-11-04
NCT07598370
A Study of LY3439539 in Participants With Alzheimer's Disease
Trial Treatment · Phase 1 · Eli Lilly and Company
QUEST Research Institute, Farmington Hills · Irvine Clinical Research, Irvine · K2 MEDICAL Research THE VILLAGES, Lady Lake · Healthy Brain Clinic, Long Beach · Inglewood Clinical, Los Angeles · K2 Medical Research, Maitland · Oakland Clinical, Oakland · AdventHealth Orlando, Orlando · Charter Research, Orlando
Registry updated 2026-11-04
NCT07773493
A Mobile Informatics Solution to Assist Caregivers in Care Coordination and Monitoring Social Engagement
Trial Treatment · University of Minnesota
University of Minnesota, Minneapolis
Registry updated 2026-11-04
NCT06540833
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease
Trial Treatment · Phase 2 · Intra-Cellular Therapies, Inc.
Advanced Research Center, Inc., Anaheim · Northwest Clinical Research Center, Bellevue · Envision Trials LLC, Bonita Springs · Clinical Research of Brandon, Brandon · New Hope Clinical Research, Charlotte · Healthcare Innovations Institute Inc, Coral Springs · Horizon Clinical Research Group, Cypress · Brain Matters Research, Delray Beach · Science Connections LLC, Doral · Homestead Associates in Research Inc, Homestead · Pharmacology Research Institute, Los Alamitos · K2 Medical Research, Maitland · AMC Research, LLC, Matthews · South Florida Research Phase I-IV, Miami · Allied Biomedical Research Institute (ABRI), Inc, Miami · Sunshine Medical Solution, Miami · Ocean Blue Medical Research Center Inc., Miami · Wellness Research Center, Miami · Wr Pri Llc, Newport Beach · ATP Clinical Research, Orange · Combined Research Orlando, Orlando · University of Texas Health Science Center at San Antonio, San Antonio · Intercoastal Medical Group, Sarasota · CenExeli Research LLC, Savannah · Psych Me Medical Research Inc, Tampa · University of South Florida, Tampa · Bio Behavioral Health, Toms River · Sunwise Clinical Research, Walnut Creek
Registry updated 2026-11-03
NCT06566170
A Real-World Comparative Study of Donanemab (LY3002813) Plus Usual Care Versus Usual Care Alone in US Participants With Early Symptomatic Alzheimer's Disease
Research · Eli Lilly and Company
Rehabilitation & Neurological Services, Huntsville
Registry updated 2026-11-03
NCT06651567
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia
Trial Treatment · Phase 2 · Intra-Cellular Therapies, Inc.
Advanced Research Center, Inc., Anaheim · SFM Clinical Research LLC, Boca Raton · Envision Trials LLC, Bonita Springs · Tufts University School of Medicine, Boston · Clinical Research of Brandon, Brandon · ATP Clinical Research, Costa Mesa · Brain Matters Research, Delray Beach · Science Connections LLC, Doral · National Institute Of Clinical Research, Garden Grove · Direct Helpers Medical Center, Inc., Hialeah · Homestead Associates in Research Inc, Homestead · Oasis Clinical Research LLC, Las Vegas · K2 Medical Research, Maitland · Neurology Associates PA, Maitland · Wellness Research Center, Miami · Vital Care Research, Miami · Advanced Clinical Research Network, Miami · Miami Jewish Health System, Miami · South Florida Research Phase I-IV, Miami · Sunshine Medical Research Studies Inc, Miami · Allied Biomedical Research Institute (ABRI), Inc, Miami · Advance Medical Research Center, Miami · Wr Pri Llc, Newport Beach · Combined Research Orlando, Orlando · Charter Research, Orlando · Eximia Clinical Research NC, Raleigh · UT Health San Antonio, San Antonio · Quantum Research Associates Corp, Tampa · Psych Me Medical Research Inc, Tampa · Bio Behavioral Health, Toms River · Sunwise Clinical Research, Walnut Creek · Premiere Research Institute at Palm Beach Neurology, West Palm Beach
Registry updated 2026-11-03
NCT07011745
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Ann Arbor · Agile Clinical Research Trials, LLC, Atlanta · Visionary Investigators Network, Aventura · Basalt · Velocity Clinical Research - Blue Ash, Blue Ash · Envision Trials LLC, Bonita Springs · Bountiful · Key Clinical Research, Bradenton · Brooklyn · Epic Medical Research, LLC - Carrolton, Carrollton · Chandler · TrialSphere Corp, Chandler · Chandler Clinical Trials, LLC, Chandler · Horizon Clinical Research Center - Houston, Cypress · Doral · National Institute Of Clinical Research, Garden Grove · Hattiesburg Clinic, Hattiesburg · Homestead · EvergreenHealth Medical Center, Kirkland · Las Vegas Clinical Trials, Las Vegas · Long Beach · Accellacare, Long Beach · Epic Medical Research, LLC - Mesquite, Mesquite · Miami · Miami Jewish Health, Miami · Milwaukee · West Clinical Research, Morehead City · Napa · Norwalk · ATP Clinical Research, Orange · Orlando · Ozark · Pasadena · Saint Paul · UT Health San Antonio, San Antonio · San Diego · Richmond Behavioral Associates, Staten Island · IPTB Clinical Research, Tampa · Bio Behavioral Health, Toms River · Walnut Clinical Research, Valley Stream · West Hills · Worcester
Registry updated 2026-11-03
NCT07741773
Assessing Treatment With High-phenolic EVOO Supplements for Neurovascular Activity
Trial Treatment · Augusta University
Georgia prevention institute, Augusta
Registry updated 2026-11-03
NCT04396873
PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
Trial Treatment · Phase 1 · National Institute of Mental Health (NIMH)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-11-02
NCT06723015
Tau PET Outcomes With Anti-amyloid Immunotherapies
Trial Treatment · Phase 2 · Mayo Clinic
Mayo Clinic, Rochester
Registry updated 2026-10-30
NCT07413744
The Gut - PRO Study
Trial Treatment · Phase 1 · University of Wisconsin, Madison
University of Wisconsin Hospitals and Clinics, Madison
Registry updated 2026-10-30
NCT06297590
A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
Trial Treatment · Phase 1 · Eli Lilly and Company
Massachusetts General Hospital (MGH), Charlestown · CenExel iResearch, LLC (CenExel iRA), Decatur · Duke University, Durham · K2 Medical Research, LLC, Maitland · Charter Research, LLC, The Villages · CenExel AMRI, Toms River
Registry updated 2026-10-29

All Alzheimer disease trials and the map

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