Childhood cancers trials in United Kingdom

In United Kingdom 158 Also abroad 2481

158 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Where
London, Newcastle upon Tyne
Age
12 years and over
People
300 worldwide
Run by
PMV Pharmaceuticals, Inc
See details and how to joinNCT04585750
Phase 1/2Taking people
A Study Evaluating the Efficacy and Safety of Risvutatug Rezetecan in Participants With Advanced Sarcomas (EMBOLD Sarcoma-202)
Where
London, Manchester
People
64 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07602777
No phaseTaking people
A Study to Assess the Incidence of Skin Cancers in Patients With Epidermolysis Bullosa Receiving Filsuvez
Where
London
People
170 worldwide
Run by
Chiesi Farmaceutici S.p.A.
See details and how to joinNCT06423573
Phase 3Taking people
Apixaban to Prevent Venous Thromboembolism in Ambulatory Lung Cancer Patients Undergoing Systemic Anticancer Treatment
Where
Dorchester, Exeter, Gorleston-on-Sea, Haverfordwest, London, Romford, Shrewsbury, Sutton in Ashfield
Age
16 years and over
People
1,456
Run by
University of Birmingham
See details and how to joinNCT07160686
Phase 1/2Taking people
A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
Where
Birmingham, Cardiff, Glasgow, Liverpool, London
Age
Up to 25 years
People
75 worldwide
Run by
Turning Point Therapeutics, Inc.
See details and how to joinNCT04094610 · EU 2023-506464-14-00
Phase 1/2Taking people
A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)
Where
London, Manchester
Age
12 years and over
People
359 worldwide
Run by
Nuvalent Inc.
See details and how to joinNCT05118789 · EU 2024-511793-71-00
Phase 2Enrolling by invitation
Long-term Follow-up of Patients Treated With Genetically Modified Autologous T Cells
Where
Glasgow, London, Manchester, Newcastle upon Tyne
Age
1 year and over
People
500 worldwide
Run by
Autolus Limited
See details and how to joinNCT03628612
Phase 2Enrolling by invitation
Long-Term Follow-Up Study After Gene-Modified Cell Treatment in Kite Studies
Where
London
People
1,500 worldwide
Run by
Kite, A Gilead Company
See details and how to joinNCT05041309 · EU 2023-507041-28-00
No phaseNot yet taking people in United Kingdom
Effectiveness of a Visual Telerehabilitation Program on Visual Perception in Children, Adolescents and Young Adults With Hemianopsia Consecutive to a Brain Tumour
Where
London
Age
10 years to 40 years
People
120 worldwide
Run by
Institut National de la Santé Et de la Recherche Médicale, France
See details and how to joinNCT07558395
No phaseNot yet taking people in United Kingdom
variaTIon in Referral Thresholds in the Chronic Lymphocytic LeukaEmia Pathway
Where
Wolverhampton
People
130
Run by
The Royal Wolverhampton Hospitals NHS Trust
See details and how to joinNCT07463976
Phase 3Taking people
Study to Evaluate the Efficacy and Safety of [177Lu]Lu-DOTA-TATE in Patients With Grade 1 and Grade 2 Advanced GEP-NET
Where
Glasgow, London
Age
12 years to 100 years
People
240 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06784752 · EU 2024-518325-15-00
Phase 1Taking people
Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
Where
London, Manchester
Age
12 years to 85 years
People
411 worldwide
Run by
Inhibrx Biosciences, Inc
See details and how to joinNCT03715933 · EU 2023-508139-29-00
No phaseTaking people
Targeted Pediatric High-Grade Glioma Therapy
Where
London
Age
12 months to 39 years
People
350 worldwide
Run by
Nationwide Children's Hospital
See details and how to joinNCT05839379
Phase 3Taking people
SIOP-HRMB: An international prospective trial on clinically high-risk medulloblastoma (HR-MB) in patients older than 3 years.
Where
Edegem, Lund
Age
Up to 64 years
People
311 worldwide
Run by
The University Of Birmingham
See details and how to join2024-510578-25-00
Phase 3Taking people
Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours
Where
Belfast, Cambridge, Cardiff, Glasgow, Lancaster, Leeds, London, Southampton
Age
11 years to 50 years
People
500 worldwide
Run by
University of Sydney
See details and how to joinNCT02582697
Phase 2Taking people
Study of Olutasidenib and Temozolomide in HGG
Where
London
Age
12 years to 39 years
People
60 worldwide
Run by
Rigel Pharmaceuticals
See details and how to joinNCT06161974
No phaseTaking people
The PROSECCA Study, Answering New Questions in Prostate Cancer
Where
Edinburgh
People
15,000
Run by
University of Edinburgh
See details and how to joinNCT06714630
No phaseNot yet taking people in United Kingdom
Use of a Novel Camera to Check the Bowel After Polyp or Tumour Removal
Where
Edinburgh
Age
16 years and over
People
30
Run by
University of Edinburgh
See details and how to joinNCT07341126
Phase 3Taking people
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
Where
Broomhall, Cambridge, Edinburgh, Glasgow, London, Manchester, Newcastle, Newcastle upon Tyne, Oxford, Sheffield, West Yorkshire
People
1,780 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT03067181
Phase 2/3Taking people
DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.
Where
Belfast, Birmingham, Bristol, Cambridge, Cardiff, Edinburgh, Glasgow, Leicester, Liverpool, London, Manchester, Metropolitan Borough of Wirral, Newcastle, Oxford, Sheffield, Southampton, Sutton
Age
1 year and over
People
30
Run by
Cancer Research UK
See details and how to joinNCT07440290
No phaseTaking people
Cerebellar Mutism Syndrome Study
Where
Liverpool
Age
Up to 18 years
People
2,000 worldwide
Run by
Copenhagen University Hospital, Rigshospitalet
See details and how to joinNCT02300766
Phase 3Taking people
A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia
Where
Aberdeen, Belfast, Birmingham, Bristol, Cambridge, Cardiff, Edinburgh, Glasgow, Leeds, Leicester, Liverpool, London, Manchester, Newcastle, Newcastle upon Tyne, Nottingham, Oxford, Plymouth, Sheffield, Southampton, Stoke, Sutton
Age
0 years to 45 years
People
6,430 worldwide
Run by
Mats Heyman
See details and how to joinNCT04307576 · EU 2022-501050-11-01
Phase 1/2Taking people
TT-702 in Patients With Advanced Solid Tumours.
Where
London, Manchester, Southampton
Age
16 years and over
People
60
Run by
Cancer Research UK
See details and how to joinNCT05272709
Phase 1Enrolling by invitation
Adoptive Cell Therapy Long-term Follow-up (LTFU) Study
Where
London, Manchester, Sutton
People
250 worldwide
Run by
USWM CT, LLC
See details and how to joinNCT03391778
Phase 1Taking people
Allogeneic T Cells Expressing T Cell Receptor-KDEL and the Chimeric Antigen Receptor CAT19 for the Treatment of Advanced CD19+ Malignancies
Where
London
Age
16 years to 65 years
People
12
Run by
University College, London
See details and how to joinNCT05391490